HitPredict

Interactor 1: DMD (P11531)
Dystrophin
Gene: DMD

Interactor 2: EIF3A (P23116)
Eukaryotic translation initiation factor 3 subunit A (eIF3a) (Centrosomin) (Eukaryotic translation initiation factor 3 subunit 10) (eIF-3-theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (p162)
Gene: EIF3A

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	24952909
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0014069 - postsynaptic density GO:0070373 - negative regulation of ERK1 and ERK2 cascade
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 3678 Mm			1 1344
+	Mm
		513821 DMD_MOUSE (1-3678): 0: 1251: 100.00		PLEC_MOUSE (500-1336): 3.1e-15: 83.9: 14.29
+	Hs
		522612 SPTN1_HUMAN (299-2573): 1.16e-137: 487: 13.44		MYH7_HUMAN (163-1194): 2.79e-34: 146: 9.36
+	Hs
		724817 SPTN1_HUMAN (299-2573): 1.16e-137: 487: 13.44		MYH9_HUMAN (842-1344): 2.55e-16: 87.2: 8.27
+	Hs
		1045418 SPTN1_HUMAN (299-2573): 1.16e-137: 487: 13.44		PLEC_HUMAN (500-1336): 1e-13: 78.9: 13.82
+	Hs
		1045423 SPTN1_HUMAN (299-2573): 1.16e-137: 487: 13.44		ITSN1_HUMAN (620-1024): 1.63e-12: 74.7: 12.10
+	Hs
		110636 H3BPE1_HUMAN (8-1421): 1.36e-45: 186: 14.41		MYH9_HUMAN (842-1344): 2.55e-16: 87.2: 8.27
+	Hs
		724839 PLEC_HUMAN (224-1863): 2.23e-44: 182: 9.01		MYH9_HUMAN (842-1344): 2.55e-16: 87.2: 8.27
+	Hs
		1068536 PLEC_HUMAN (224-1863): 2.23e-44: 182: 9.01		PLEC_HUMAN (500-1336): 1e-13: 78.9: 13.82
+	Mm
		93578 PLEC_MOUSE (228-1857): 4.09e-43: 177: 8.79		DESP_MOUSE (466-1000): 3.18e-10: 67.4: 13.79
+	Hs
		725073 MACF1_HUMAN (171-1407): 2.95e-20: 102: 14.64		MYH9_HUMAN (842-1344): 2.55e-16: 87.2: 8.27
+	Hs
		1078871 SYNE1_HUMAN (184-1938): 4.95e-24: 114: 10.48		ITSN1_HUMAN (620-1024): 1.63e-12: 74.7: 12.10
+	Hs
		724786 DYST_HUMAN (1788-3172): 5.49e-19: 98.2: 10.99		MYH9_HUMAN (842-1344): 2.55e-16: 87.2: 8.27
+	Hs
		1068700 MACF1_HUMAN (171-1407): 2.95e-20: 102: 14.64		PLEC_HUMAN (500-1336): 1e-13: 78.9: 13.82
+	Hs
		724781 SPTB2_HUMAN (1657-3158): 1.02e-17: 93.6: 10.09		MYH9_HUMAN (842-1344): 2.55e-16: 87.2: 8.27
+	Hs
		974083 DYST_HUMAN (1788-3172): 5.49e-19: 98.2: 10.99		ITSN1_HUMAN (620-1024): 1.63e-12: 74.7: 12.10
+	Hs
		963335 SPTB2_HUMAN (1657-3158): 1.02e-17: 93.6: 10.09		ITSN1_HUMAN (620-1024): 1.63e-12: 74.7: 12.10
+	Hs
		974160 DYST_HUMAN (1788-3172): 5.49e-19: 98.2: 10.99		ITSN2_HUMAN (745-1157): 5.19e-10: 66.6: 12.32
+	Hs
		164575 SPTN2_HUMAN (2570-3095): 5.09e-11: 71.6: 14.12		MYH9_HUMAN (842-1344): 2.55e-16: 87.2: 8.27
+	Hs
		1059285 GOGB1_HUMAN (2663-3214): 1e-09: 67.4: 9.58		ITSN2_HUMAN (745-1157): 5.19e-10: 66.6: 12.32