HitPredict

Interactor 1: DMD (P11532)
Dystrophin
Gene: DMD

Interactor 2: SNTB2 (Q13425)
Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin-3) (SNT3) (Syntrophin-like) (SNTL)
Gene: SNTB2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.700

Property	Details
Experiments	8576247, 28514442, 33961781, 22937058
Identification Methods	unspecified method, affinity chromatography technology, anti tag coimmunoprecipitation, coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003779 - actin binding GO:0005886 - plasma membrane GO:0016010 - dystrophin-associated glycoprotein complex GO:0032991 - protein-containing complex GO:0045202 - synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 3685 Hs			1 540
+	Hs
		513860 DMD_HUMAN (1-3685): 0: 1187: 100.00		SNTB1_HUMAN (24-539): 2.43e-151: 445: 55.30
+	Mm
		513793 DMD_MOUSE (1-3685): 0: 1155: 90.37		SNTB2_MOUSE (16-540): 1.09e-162: 474: 95.05
+	Hs
		513856 DMD_HUMAN (1-3685): 0: 1187: 100.00		SNTA1_HUMAN (16-539): 1.35e-142: 422: 45.49
+	Mm
		513810 DMD_MOUSE (1-3685): 0: 1155: 90.37		SNTB1_MOUSE (24-539): 6.08e-149: 439: 54.53
+	Mm
		57227 DMD_MOUSE (1-3685): 0: 1155: 90.37		A2AKD7_MOUSE (16-539): 1.22e-145: 430: 45.49
+	Mm
		513788 DMD_MOUSE (1-3685): 0: 1155: 90.37		Q3UVD6_MOUSE (16-539): 1.47e-145: 429: 45.30
+	Mm
		513792 DMD_MOUSE (1-3685): 0: 1155: 90.37		SNTA1_MOUSE (16-539): 1.34e-142: 422: 45.15
+	Hs
		513904 DMD_HUMAN (1-3685): 0: 1187: 100.00		SNTG2_HUMAN (103-536): 2.07e-110: 341: 24.04
+	Hs
		513902 DMD_HUMAN (1-3685): 0: 1187: 100.00		SNTG1_HUMAN (103-536): 1.35e-108: 335: 22.66
+	Mm
		513808 DMD_MOUSE (1-3685): 0: 1155: 90.37		SNTG2_MOUSE (103-536): 1.54e-113: 349: 24.47
+	Mm
		513809 DMD_MOUSE (1-3685): 0: 1155: 90.37		SNTG1_MOUSE (103-536): 8.15e-106: 328: 22.56
+	Mm
		1142421 Q6P6L2_MOUSE (12-762): 0: 664: 55.79		SNTB2_MOUSE (16-540): 1.09e-162: 474: 95.05
+	Mm
		1160362 Q6P6L2_MOUSE (12-762): 0: 664: 55.79		SNTB1_MOUSE (24-539): 6.08e-149: 439: 54.53
+	Hs
		1046428 Q14205_HUMAN (2980-3685): 0: 651: 100.00		SNTB1_HUMAN (24-539): 2.43e-151: 445: 55.30
+	Mm
		1113337 Q6P6L2_MOUSE (12-762): 0: 664: 55.79		Q3UVD6_MOUSE (16-539): 1.47e-145: 429: 45.30
+	Hs
		1033832 Q14205_HUMAN (2980-3685): 0: 651: 100.00		SNTA1_HUMAN (16-539): 1.35e-142: 422: 45.49
+	Mm
		1160360 Q6P6L2_MOUSE (12-762): 0: 664: 55.79		SNTG2_MOUSE (103-536): 1.54e-113: 349: 24.47
+	Mm
		1160361 Q6P6L2_MOUSE (12-762): 0: 664: 55.79		SNTG1_MOUSE (103-536): 8.15e-106: 328: 22.56
+	Mm
		985506 DRP2_MOUSE (2786-3680): 1.2e-152: 504: 55.18		SNTG2_MOUSE (103-536): 1.54e-113: 349: 24.47
+	Mm
		985507 DRP2_MOUSE (2786-3680): 1.2e-152: 504: 55.18		SNTG1_MOUSE (103-536): 8.15e-106: 328: 22.56