HitPredict

Interactor 1: MPRI (P11717)
Cation-independent mannose-6-phosphate receptor (CI Man-6-P receptor) (CI-MPR) (M6PR) (300 kDa mannose 6-phosphate receptor) (MPR 300) (Insulin-like growth factor 2 receptor) (Insulin-like growth factor II receptor) (IGF-II receptor) (M6P/IGF2 receptor) (M6P/IGF2R) (CD antigen CD222)
Gene: IGF2R

Interactor 2: EWS (Q01844)
RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein)
Gene: EWSR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	24999758
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 2491 Hs			1 656
+	Hs
		363092 FINC_HUMAN (1769-2040): 1.28e-16: 89.5: 14.63		EWS_HUMAN (1-656): 1.54e-47: 179: 100.00
+	Hs
		439240 MMP2_HUMAN (1785-1890): 9.46e-19: 95.2: 18.18		CO4A6_HUMAN (3-482): 5.99e-30: 128: 12.17
+	Hs
		362885 FINC_HUMAN (1769-2040): 1.28e-16: 89.5: 14.63		FUS_HUMAN (55-545): 1.15e-31: 131: 30.35
+	Hs
		358587 MMP2_HUMAN (1785-1890): 9.46e-19: 95.2: 18.18		CO2A1_HUMAN (3-462): 5.09e-19: 94.1: 8.59
+	Hs
		358454 MMP2_HUMAN (1785-1890): 9.46e-19: 95.2: 18.18		CO1A1_HUMAN (2-506): 1.09e-18: 92.9: 14.74
+	Hs
		358595 MMP9_HUMAN (1785-1890): 4.44e-17: 90.2: 17.27		CO2A1_HUMAN (3-462): 5.09e-19: 94.1: 8.59
+	Hs
		358441 FINC_HUMAN (1769-2040): 1.28e-16: 89.5: 14.63		CO1A1_HUMAN (2-506): 1.09e-18: 92.9: 14.74
+	Hs
		436001 MMP2_HUMAN (1785-1890): 9.46e-19: 95.2: 18.18		CO1A2_HUMAN (4-301): 3.82e-16: 84.9: 12.95
+	Hs
		436005 MMP9_HUMAN (1785-1890): 4.44e-17: 90.2: 17.27		CO1A2_HUMAN (4-301): 3.82e-16: 84.9: 12.95
+	Hs
		358647 MMP2_HUMAN (1785-1890): 9.46e-19: 95.2: 18.18		CO4A1_HUMAN (4-375): 8.83e-14: 77.2: 11.08
+	Hs
		363093 FINC_HUMAN (1769-2040): 1.28e-16: 89.5: 14.63		CO7A1_HUMAN (3-334): 1.88e-15: 82.9: 8.07
+	Hs
		439220 MMP2_HUMAN (1785-1890): 9.46e-19: 95.2: 18.18		CO4A2_HUMAN (401-655): 7.23e-13: 74.5: 15.99
+	Hs
		358650 MMP9_HUMAN (1785-1890): 4.44e-17: 90.2: 17.27		CO4A1_HUMAN (4-375): 8.83e-14: 77.2: 11.08
+	Hs
		441053 MMP9_HUMAN (1785-1890): 4.44e-17: 90.2: 17.27		CO4A2_HUMAN (401-655): 7.23e-13: 74.5: 15.99