HitPredict

Interactor 1: KCC2G (P11730)
Calcium/calmodulin-dependent protein kinase type II subunit gamma (CaM kinase II subunit gamma) (CaMK-II subunit gamma) (EC 2.7.11.17)
Gene: Camk2g

Interactor 2: TAU (P19332)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: Mapt

Species: Rattus norvegicus

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	32357304
Identification Methods	cross-linking study
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0014069 - postsynaptic density GO:0043005 - neuron projection
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 527 Rn			1 752
+	Rn
		94132 KCC2G_RAT (1-527): 0: 600: 100.00		F1LST4_RAT (1-751): 5.68e-95: 314: 99.87
+	Rn
		439487 KCC2B_RAT (1-527): 0: 585: 82.66		TAU_RAT (1-752): 2.4e-95: 314: 100.00
+	Rn
		94121 KCC2B_RAT (1-527): 0: 585: 82.66		F1LST4_RAT (1-751): 5.68e-95: 314: 99.87
+	Mm
		498111 KCC2G_MOUSE (1-527): 0: 593: 91.49		TAU_MOUSE (1-752): 1.92e-82: 279: 89.52
+	Rn
		506692 KCC2A_RAT (1-523): 0: 542: 75.14		TAU_RAT (1-752): 2.4e-95: 314: 100.00
+	Rn
		94129 KCC2A_RAT (1-523): 0: 542: 75.14		F1LST4_RAT (1-751): 5.68e-95: 314: 99.87
+	Hs
		92372 E9PBG7_HUMAN (1-527): 0: 581: 80.08		TAU_HUMAN (1-752): 2.05e-72: 253: 71.86
+	Hs
		496977 KCC2D_HUMAN (1-527): 0: 564: 78.56		TAU_HUMAN (1-752): 2.05e-72: 253: 71.86
+	Hs
		497824 KCC2A_HUMAN (1-523): 0: 542: 75.34		TAU_HUMAN (1-752): 2.05e-72: 253: 71.86
+	Mm
		592770 KCC2D_MOUSE (1-527): 0: 564: 78.56		MTAP2_MOUSE (49-752): 4.26e-36: 149: 25.07
+	Hs
		159141 CSKP_HUMAN (10-493): 2.92e-142: 434: 32.87		TAU_HUMAN (1-752): 2.05e-72: 253: 71.86
+	Rn
		506773 KCC2A_RAT (1-523): 0: 542: 75.14		PCLO_RAT (1-751): 2.97e-14: 79.3: 9.20
+	Mm
		498146 DCLK1_MOUSE (11-272): 7.8e-66: 228: 44.15		TAU_MOUSE (1-752): 1.92e-82: 279: 89.52
+	Hs
		497299 DCLK2_HUMAN (12-335): 3.3e-66: 230: 37.62		TAU_HUMAN (1-752): 2.05e-72: 253: 71.86
+	Hs
		496976 KCC2B_HUMAN (274-527): 4.04e-54: 195: 53.54		TAU_HUMAN (1-752): 2.05e-72: 253: 71.86
+	Hs
		1083233 KCC4_HUMAN (10-304): 5.78e-73: 241: 43.43		CABIN_HUMAN (103-561): 3.85e-12: 72.2: 12.26