HitPredict

Interactor 1: PABP1 (P11940)
Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1)
Gene: PABPC1

Interactor 2: IF4B (P23588)
Eukaryotic translation initiation factor 4B (eIF-4B)
Gene: EIF4B

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	1.00	0.768

Property	Details
Experiments	29228324, 11274152
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 636 Hs			1 611
+	Hs
		516339 PABP1_HUMAN (1-636): 0: 582: 100.00		PABP1_HUMAN (49-537): 3.4e-25: 112: 10.22
+	Hs
		516689 PABP1_HUMAN (1-636): 0: 582: 100.00		PABP3_HUMAN (54-547): 1.45e-22: 104: 11.07
+	Hs
		516495 PABP1_HUMAN (1-636): 0: 582: 100.00		PABP4_HUMAN (49-389): 1.92e-21: 100: 9.72
+	Hs
		474021 PABP4_HUMAN (1-635): 0: 534: 74.69		PAB4L_HUMAN (6-198): 1.72e-27: 116: 13.40
+	Zm
		8143 A0A1D6ELH4_MAIZE (2-467): 9.33e-68: 235: 25.36		A0A1D6ELH4_MAIZE (94-497): 7.01e-41: 159: 10.76
+	Sc
		376562 PABP_YEAST (2-335): 1.06e-64: 225: 26.71		PABP_YEAST (7-185): 1.17e-23: 107: 16.58
+	Sc
		376663 PABP_YEAST (2-335): 1.06e-64: 225: 26.71		NSR1_YEAST (84-187): 1.96e-10: 65.3: 20.00
+	Hs
		474034 PABP5_HUMAN (6-179): 5.04e-39: 149: 25.26		PAB4L_HUMAN (6-198): 1.72e-27: 116: 13.40
+	Hs
		516635 PABP5_HUMAN (6-179): 5.04e-39: 149: 25.26		PABP1_HUMAN (49-537): 3.4e-25: 112: 10.22
+	Hs
		1119141 PABP5_HUMAN (6-179): 5.04e-39: 149: 25.26		PAP1L_HUMAN (49-389): 3.99e-23: 105: 10.28
+	Mm
		665745 TIA1_MOUSE (4-172): 1.01e-34: 137: 27.51		PABP1_MOUSE (49-537): 6.94e-25: 111: 10.22
+	Hs
		516355 NUCL_HUMAN (3-89): 2.56e-19: 94.1: 33.33		PABP1_HUMAN (49-537): 3.4e-25: 112: 10.22