HitPredict

Interactor 1: PABP1 (P11940)
Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1)
Gene: PABPC1

Interactor 2: CLK2 (P49760)
Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2)
Gene: CLK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	23602568
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	GO:0005634 - nucleus
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 636 Hs			1 499
+	Hs
		516417 PABP1_HUMAN (1-636): 0: 582: 100.00		CLK3_HUMAN (1-499): 1.7e-136: 409: 59.32
+	Hs
		516362 PABP1_HUMAN (1-636): 0: 582: 100.00		CDK2_HUMAN (160-488): 4.25e-133: 389: 24.70
+	Hs
		834033 PABP4_HUMAN (1-635): 0: 534: 74.69		CLK3_HUMAN (1-499): 1.7e-136: 409: 59.32
+	Hs
		516508 PABP1_HUMAN (1-636): 0: 582: 100.00		DYR1A_HUMAN (108-485): 6.52e-105: 331: 28.50
+	Hs
		1031320 PABP4_HUMAN (1-635): 0: 534: 74.69		DYR1A_HUMAN (108-485): 6.52e-105: 331: 28.50
+	Hs
		833945 PABP5_HUMAN (6-179): 5.04e-39: 149: 25.26		CLK2_HUMAN (1-499): 1.97e-147: 432: 100.00
+	Hs
		834096 PABP5_HUMAN (6-179): 5.04e-39: 149: 25.26		CLK3_HUMAN (1-499): 1.7e-136: 409: 59.32
+	Hs
		582139 NUCL_HUMAN (3-89): 2.56e-19: 94.1: 33.33		CLK1_HUMAN (1-484): 3.66e-144: 424: 53.31
+	Hs
		414728 NUCL_HUMAN (3-89): 2.56e-19: 94.1: 33.33		CDK1_HUMAN (160-485): 3.05e-114: 340: 23.95
+	Hs
		582281 NUCL_HUMAN (3-89): 2.56e-19: 94.1: 33.33		DYR1A_HUMAN (108-485): 6.52e-105: 331: 28.50