HitPredict

Interactor 1: PABP1 (P11940)
Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1)
Gene: PABPC1

Interactor 2: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	15324660, 17353931
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005925 - focal adhesion GO:0016020 - membrane and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 636 Hs			1 247
+	Hs
		516444 PABP1_HUMAN (1-636): 0: 582: 100.00		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		909516 PABP4_HUMAN (1-635): 0: 534: 74.69		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		516374 PABP1_HUMAN (1-636): 0: 582: 100.00		1433S_HUMAN (2-245): 1.86e-98: 289: 65.16
+	Hs
		683319 PABP4_HUMAN (1-635): 0: 534: 74.69		1433B_HUMAN (2-247): 1.91e-109: 317: 75.40
+	Hs
		927003 PABP4_HUMAN (1-635): 0: 534: 74.69		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		646864 PABP4_HUMAN (1-635): 0: 534: 74.69		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Mm
		449418 NUCL_MOUSE (166-386): 2.07e-20: 97.6: 19.56		1433E_MOUSE (1-244): 2.02e-141: 398: 63.53
+	Hs
		582177 NUCL_HUMAN (3-89): 2.56e-19: 94.1: 33.33		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	Hs
		582211 NUCL_HUMAN (3-89): 2.56e-19: 94.1: 33.33		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		582075 NUCL_HUMAN (3-89): 2.56e-19: 94.1: 33.33		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33