Protein: TNPO1
Transportin-1 (Importin beta-2) (Karyopherin beta-2) (M9 region interaction protein) (MIP)

Gene: TNPO1
Organism: Homo sapiens
Interactions: 209
UniProt ID: Q92973

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005929 - cilium

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

919198

RAN
GTP-binding nuclear protein Ran

6

17

Small-scale

0.944

High

453517

ROA1
Heterogeneous nuclear ribonucleoprotein A1

2

7

Small-scale

0.812

High

1130405

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

4

Small-scale

0.789

High

506469

RALB
Ras-related protein Ral-B

2

5

High-throughput

0.737

High

925496

RAC1
Ras-related C3 botulinum toxin substrate 1

2

10

High-throughput

0.737

High

1223625

ULK2
Serine/threonine-protein kinase ULK2

1

1

Small-scale

0.724

High

853016

HNRPM
Heterogeneous nuclear ribonucleoprotein M

1

2

Small-scale

0.716

High

134943

IMA3
Importin subunit alpha-3

1

20

High-throughput

0.691

High

549915

PHKG2
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform

1

4

High-throughput

0.691

High

609984

ROA2
Heterogeneous nuclear ribonucleoproteins A2/B1

1

7

High-throughput

0.691

High

853409

IMA1
Importin subunit alpha-1

1

20

High-throughput

0.691

High

930334

UBC9
SUMO-conjugating enzyme UBC9

1

2

High-throughput

0.691

High

1060859

IMB1
Importin subunit beta-1

1

8

High-throughput

0.691

High

1273247

SIK3
Serine/threonine-protein kinase SIK3

1

1

High-throughput

0.691

High

1273200

TMA16
Translation machinery-associated protein 16

3

2

High-throughput

0.675

High

834652

NU153
Nuclear pore complex protein Nup153

3

20

Small-scale

0.662

High

1190554

HEAT3
HEAT repeat-containing protein 3

1

0

High-throughput

0.656

High

228265

PRKN
E3 ubiquitin-protein ligase parkin

3

11

High-throughput

0.640

High

1267062

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

2

6

Small-scale

0.639

High

1273235

NXF1
Nuclear RNA export factor 1

2

6

Small-scale

0.629

High

726972

FUS
RNA-binding protein FUS

2

5

Small-scale

0.629

High

163086

XPO1
Exportin-1

1

10

Small-scale

0.618

High

727300

NU214
Nuclear pore complex protein Nup214

1

20

Small-scale

0.618

High

822119

KC1A
Casein kinase I isoform alpha

1

5

High-throughput

0.618

High

1273215

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

3

High-throughput

0.618

High

1273232

PD1L1
Programmed cell death 1 ligand 1

2

16

High-throughput

0.611

High

1220521

TARG1
Trafficking regulator of GLUT4 1

3

2

High-throughput

0.609

High

1273203

VSIG2
V-set and immunoglobulin domain-containing protein 2

3

7

High-throughput

0.609

High

338800

EGFR
Epidermal growth factor receptor

2

10

High-throughput

0.594

High

322960

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

2

5

High-throughput

0.584

High

779852

CCNF
Cyclin-F

2

7

High-throughput

0.584

High

1273214

ACE2
Angiotensin-converting enzyme 2

2

2

Small-scale

0.584

High

1237305

SIGL1
SIGLEC family-like protein 1

2

5

High-throughput

0.574

High

347506

MYC
Myc proto-oncogene protein

2

7

High-throughput

0.571

High

447982

SRP19
Signal recognition particle 19 kDa protein

1

2

Small-scale

0.561

High

1273248

NOSIP
Nitric oxide synthase-interacting protein

1

3

Small-scale

0.561

High

1074381

STIL
SCL-interrupting locus protein

2

0

High-throughput

0.559

High

1273228

SLX9
Ribosome biogenesis protein SLX9 homolog

2

1

Small-scale

0.558

High

274122

XRP2
Protein XRP2

1

4

High-throughput

0.536

High

306841

VAMP5
Vesicle-associated membrane protein 5

1

2

High-throughput

0.536

High

362260

GLPA
Glycophorin-A

1

4

High-throughput

0.536

High

383912

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

10

High-throughput

0.536

High

454739

TACD2
Tumor-associated calcium signal transducer 2

1

2

High-throughput

0.536

High

623551

AKAP5
A-kinase anchor protein 5

1

1

High-throughput

0.536

High

639623

TNR5
Tumor necrosis factor receptor superfamily member 5

1

9

High-throughput

0.536

High

646253

STOM
Stomatin

1

7

High-throughput

0.536

High

675212

CLIP1
CAP-Gly domain-containing linker protein 1

1

5

High-throughput

0.536

High

682923

HNRH1
Heterogeneous nuclear ribonucleoprotein H

1

6

High-throughput

0.536

High

796783

RANG
Ran-specific GTPase-activating protein

1

20

High-throughput

0.536

High

801747

RAGP1
Ran GTPase-activating protein 1

1

4

High-throughput

0.536

High

804307

NOTC1
Neurogenic locus notch homolog protein 1

1

3

High-throughput

0.536

High

813655

CAPZB
F-actin-capping protein subunit beta

1

2

High-throughput

0.536

High

818325

SOX2
Transcription factor SOX-2

1

6

High-throughput

0.536

High

834809

RBP2
E3 SUMO-protein ligase RanBP2

1

7

High-throughput

0.536

High

852123

ROA3
Heterogeneous nuclear ribonucleoprotein A3

1

9

High-throughput

0.536

High

872918

ARSF
Arylsulfatase F

1

1

High-throughput

0.536

High

903835

NTF2
Nuclear transport factor 2

1

7

High-throughput

0.536

High

957903

EFNB1
Ephrin-B1

1

5

High-throughput

0.536

High

967323

EWS
RNA-binding protein EWS

1

7

High-throughput

0.536

High

1026098

ROA0
Heterogeneous nuclear ribonucleoprotein A0

1

9

High-throughput

0.536

High

1035163

FOXE3
Forkhead box protein E3

1

1

High-throughput

0.536

High

1035268

NFAC2
Nuclear factor of activated T-cells, cytoplasmic 2

1

5

Small-scale

0.536

High

1048166

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

9

High-throughput

0.536

High

1052120

MAP7
Ensconsin

1

10

High-throughput

0.536

High

1059494

FXYD3
FXYD domain-containing ion transport regulator 3

1

2

High-throughput

0.536

High

1201118

THOC4
THO complex subunit 4

1

5

High-throughput

0.536

High

1273201

MACIR
Macrophage immunometabolism regulator

1

1

High-throughput

0.536

High

1273205

QKI
KH domain-containing RNA-binding protein QKI

1

3

High-throughput

0.536

High

1273206

CDC5L
Cell division cycle 5-like protein

1

4

High-throughput

0.536

High

1273210

OVOL2
Transcription factor Ovo-like 2

1

12

High-throughput

0.536

High

1273212

KIFC1
Kinesin-like protein KIFC1

1

3

High-throughput

0.536

High

1273217

F234A
Protein FAM234A

1

5

High-throughput

0.536

High

1273239

NUP50
Nuclear pore complex protein Nup50

1

20

High-throughput

0.536

High

1273244

TN13B
Tumor necrosis factor ligand superfamily member 13B

1

6

High-throughput

0.536

High

1273253

SAR1B
Small COPII coat GTPase SAR1B

1

1

High-throughput

0.536

High

1273208

RGPD5
RANBP2-like and GRIP domain-containing protein 5/6

1

20

Small-scale

0.527

High

147543

SOCS6
Suppressor of cytokine signaling 6

1

4

High-throughput

0.515

High

238808

UGDH
UDP-glucose 6-dehydrogenase

1

2

High-throughput

0.515

High

207083

XRCC3
DNA repair protein XRCC3

1

0

High-throughput

0.513

High

439847

NEP
Neprilysin

1

0

Small-scale

0.513

High

1273204

AP4AT
AP-4 complex accessory subunit Tepsin

1

0

High-throughput

0.513

High

1273234

SUCO
SUN domain-containing ossification factor

1

0

High-throughput

0.513

High

1273238

DCTN4
Dynactin subunit 4

1

0

High-throughput

0.513

High

858024

NUP98
Nuclear pore complex protein Nup98-Nup96

1

20

Small-scale

0.501

High

1199029

PABP2
Polyadenylate-binding protein 2

1

4

Small-scale

0.501

High

58455

F234B
Protein FAM234B

1

5

High-throughput

0.489

High

600638

EPHA1
Ephrin type-A receptor 1

1

6

High-throughput

0.489

High

1067562

P2RY6
P2Y purinoceptor 6

1

13

High-throughput

0.489

High

1166522

BTNL9
Butyrophilin-like protein 9

1

3

High-throughput

0.489

High

1184602

ARMX6
Protein ARMCX6

1

4

High-throughput

0.489

High

1202521

CMTD1
Catechol O-methyltransferase domain-containing protein 1

1

7

High-throughput

0.489

High

1233009

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

1

High-throughput

0.489

High

1252991

F174A
Membrane protein FAM174A

1

4

High-throughput

0.489

High

1273218

UN93B
Protein unc-93 homolog B1

1

4

High-throughput

0.489

High

1273221

PACC1
Proton-activated chloride channel

1

5

High-throughput

0.489

High

1273240

CAH14
Carbonic anhydrase 14

1

8

High-throughput

0.489

High

1273251

GPR45
Probable G-protein coupled receptor 45

1

8

High-throughput

0.489

High

1273252

NPTN
Neuroplastin

1

8

High-throughput

0.489

High

119471

LEG9
Galectin-9

1

5

High-throughput

0.479

High

165867

KDM6B
Lysine-specific demethylase 6B

1

3

Small-scale

0.479

High

244745

BRD4
Bromodomain-containing protein 4

1

5

High-throughput

0.479

High

255970

OBSL1
Obscurin-like protein 1

1

2

High-throughput

0.479

High

273926

NU155
Nuclear pore complex protein Nup155

1

3

High-throughput

0.479

High

295084

RECQ4
ATP-dependent DNA helicase Q4

1

7

High-throughput

0.479

High

299441

UBXN7
UBX domain-containing protein 7

1

6

High-throughput

0.479

High

455728

PARP1
Poly [ADP-ribose] polymerase 1

1

10

High-throughput

0.479

High

487647

ANDR
Androgen receptor

1

10

High-throughput

0.479

High

530716

ITA4
Integrin alpha-4

1

3

High-throughput

0.479

High

546871

PPAP
Prostatic acid phosphatase

1

1

High-throughput

0.479

High

553352

RFA2
Replication protein A 32 kDa subunit

1

5

High-throughput

0.479

High

569939

CEBPB
CCAAT/enhancer-binding protein beta

1

8

High-throughput

0.479

High

577050

PTPRA
Receptor-type tyrosine-protein phosphatase alpha

1

10

High-throughput

0.479

High

617059

PTPRE
Receptor-type tyrosine-protein phosphatase epsilon

1

11

High-throughput

0.479

High

651867

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

6

High-throughput

0.479

High

660867

PTPRM
Receptor-type tyrosine-protein phosphatase mu

1

10

High-throughput

0.479

High

670146

MARCS
Myristoylated alanine-rich C-kinase substrate

1

1

Small-scale

0.479

High

684936

STIP1
Stress-induced-phosphoprotein 1

1

8

High-throughput

0.479

High

749743

BRCA1
Breast cancer type 1 susceptibility protein

1

5

High-throughput

0.479

High

750389

COIL
Coilin

1

2

High-throughput

0.479

High

839279

5HT6R
5-hydroxytryptamine receptor 6

1

5

Small-scale

0.479

High

916296

RL23A
Large ribosomal subunit protein uL23

1

3

Small-scale

0.479

High

924768

GRB2
Growth factor receptor-bound protein 2

1

4

High-throughput

0.479

High

927378

1433Z
14-3-3 protein zeta/delta

1

7

High-throughput

0.479

High

941260

RNF4
E3 ubiquitin-protein ligase RNF4

1

5

High-throughput

0.479

High

974402

CREM
cAMP-responsive element modulator

1

2

Small-scale

0.479

High

998952

EP300
Histone acetyltransferase p300

1

14

High-throughput

0.479

High

1030400

G3BP1
Ras GTPase-activating protein-binding protein 1

1

7

High-throughput

0.479

High

1036780

SQSTM
Sequestosome-1

1

6

High-throughput

0.479

High

1042209

CUL3
Cullin-3

1

8

High-throughput

0.479

High

1061539

CUL7
Cullin-7

1

3

High-throughput

0.479

High

1062186

HAPR1
HUWE1-associated protein modifying stress responses 1

1

5

High-throughput

0.479

High

1080201

EZH2
Histone-lysine N-methyltransferase EZH2

1

6

High-throughput

0.479

High

1088221

PTPRN
Receptor-type tyrosine-protein phosphatase-like N

1

18

High-throughput

0.479

High

1101201

CL16A
Protein CLEC16A

1

2

High-throughput

0.479

High

1148710

VIR
Protein virilizer homolog

1

4

High-throughput

0.479

High

1167232

DPPA3
Developmental pluripotency-associated protein 3

1

2

High-throughput

0.479

High

1171092

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.479

High

1174273

MOB3C
MOB kinase activator 3C

1

2

High-throughput

0.479

High

1188663

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

5

High-throughput

0.479

High

1198120

TM11B
Transmembrane protease serine 11B

1

6

High-throughput

0.479

High

1199662

ZN598
E3 ubiquitin-protein ligase ZNF598

1

7

High-throughput

0.479

High

1222205

YAF2
YY1-associated factor 2

1

2

High-throughput

0.479

High

1231292

RHG24
Rho GTPase-activating protein 24

1

5

High-throughput

0.479

High

1239142

ZBT38
Zinc finger and BTB domain-containing protein 38

1

11

Small-scale

0.479

High

1239705

NHLC2
NHL repeat-containing protein 2

1

1

High-throughput

0.479

High

1242619

TNR6A
Trinucleotide repeat-containing gene 6A protein

1

10

High-throughput

0.479

High

1260266

PTPM1
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1

1

10

High-throughput

0.479

High

1270353

HDAC2
Histone deacetylase 2

1

6

High-throughput

0.479

High

1273199

SPDLY
Protein Spindly

1

3

High-throughput

0.479

High

1273202

DDRGK
DDRGK domain-containing protein 1

1

5

High-throughput

0.479

High

1273207

NECD
Necdin

1

7

Small-scale

0.479

High

1273209

ACON
Aconitate hydratase, mitochondrial

1

1

High-throughput

0.479

High

1273211

DUS23
Dual specificity protein phosphatase 23

1

19

High-throughput

0.479

High

1273216

CCDC8
Coiled-coil domain-containing protein 8

1

5

High-throughput

0.479

High

1273219

PKHA4
Pleckstrin homology domain-containing family A member 4

1

16

High-throughput

0.479

High

1273220

EGLN3
Prolyl hydroxylase EGLN3

1

4

High-throughput

0.479

High

1273222

ECT2
Protein ECT2

1

7

High-throughput

0.479

High

1273223

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

2

High-throughput

0.479

High

1273224

ANLN
Anillin

1

10

High-throughput

0.479

High

1273225

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

9

High-throughput

0.479

High

1273230

TLS1
Splicing factor C9orf78

1

6

High-throughput

0.479

High

1273231

WWOX
WW domain-containing oxidoreductase

1

4

High-throughput

0.479

High

1273233

KIF17
Kinesin-like protein KIF17

1

1

Small-scale

0.479

High

1273237

ZRAN1
Ubiquitin thioesterase ZRANB1

1

14

High-throughput

0.479

High

1273242

TRI33
E3 ubiquitin-protein ligase TRIM33

1

11

High-throughput

0.479

High

1273243

HDAC5
Histone deacetylase 5

1

9

High-throughput

0.479

High

1273246

FND3A
Fibronectin type-III domain-containing protein 3A

1

6

High-throughput

0.479

High

1273249

ZN330
Zinc finger protein 330

1

3

High-throughput

0.479

High

1014233

MN1
Transcriptional activator MN1

1

0

Small-scale

0.458

High

1075147

TCEA2
Transcription elongation factor A protein 2

1

0

High-throughput

0.458

High

1119578

MIDN
Midnolin

1

0

High-throughput

0.458

High

1273236

DAXX
Death domain-associated protein 6

1

0

Small-scale

0.458

High

1273226

DISC1
Disrupted in schizophrenia 1 protein

1

2

High-throughput

0.457

High

435716

IGF1R
Insulin-like growth factor 1 receptor

1

13

High-throughput

0.457

High

321155

PTBP3
Polypyrimidine tract-binding protein 3

1

4

High-throughput

0.445

High

395385

A4
Amyloid-beta precursor protein

1

3

Small-scale

0.445

High

497394

TAU
Microtubule-associated protein tau

1

9

High-throughput

0.445

High

529511

CFTR
Cystic fibrosis transmembrane conductance regulator

1

8

High-throughput

0.445

High

581819

VCAM1
Vascular cell adhesion protein 1

1

5

High-throughput

0.445

High

968637

TAGL
Transgelin

1

4

High-throughput

0.445

High

1158944

ZFP1
Zinc finger protein 1 homolog

1

10

High-throughput

0.445

High

101035

APRIO
Alternative prion protein

1

4

High-throughput

0.437

High

353299

CD4
T-cell surface glycoprotein CD4

1

1

Small-scale

0.437

High

385296

NTRK1
High affinity nerve growth factor receptor

1

11

High-throughput

0.437

High

721079

RFA3
Replication protein A 14 kDa subunit

1

5

High-throughput

0.437

High

881661

PEX3
Peroxisomal biogenesis factor 3

1

1

High-throughput

0.437

High

1087578

CAH9
Carbonic anhydrase 9

1

8

Small-scale

0.437

High

1148159

RNF43
E3 ubiquitin-protein ligase RNF43

1

7

High-throughput

0.437

High

1165816

LMBRL
Protein LMBR1L

1

5

High-throughput

0.437

High

1185033

PCAT2
Lysophosphatidylcholine acyltransferase 2

1

3

High-throughput

0.437

High

1220797

ASXL1
Polycomb group protein ASXL1

1

4

High-throughput

0.437

High

1222061

S15A3
Solute carrier family 15 member 3

1

3

High-throughput

0.437

High

1263877

CLC4D
C-type lectin domain family 4 member D

1

5

High-throughput

0.437

High

1273016

PTPR2
Receptor-type tyrosine-protein phosphatase N2

1

16

High-throughput

0.437

High

1273227

TMPS4
Transmembrane protease serine 4

1

6

High-throughput

0.437

High

1273229

ATD3A
ATPase family AAA domain-containing protein 3A

1

5

High-throughput

0.437

High

1273241

CLC4E
C-type lectin domain family 4 member E

1

5

High-throughput

0.437

High

1273250

DJC15
DnaJ homolog subfamily C member 15

1

3

High-throughput

0.437

High

1273245

ITM2B
Integral membrane protein 2B

1

0

High-throughput

0.426

High

1096

SIM26
Small integral membrane protein 26

1

5

High-throughput

0.407

High

99648

F5H1C8
Solute carrier family 15 member 3

1

3

High-throughput

0.407

High

1241561

MOT11
Monocarboxylate transporter 11

1

5

High-throughput

0.407

High

1273213

TX101
Testis-expressed protein 101

1

3

High-throughput

0.407

High

1127377

T255A
Transmembrane protein 255A

1

0

High-throughput

0.279

Low

1132946

CSCL2
CSC1-like protein 2

1

0

High-throughput

0.279

Low

1137002

PR14L
Protein PRR14L

1

0

High-throughput

0.279

Low

1169260

MBOA1
Lysophospholipid acyltransferase 1

1

0

High-throughput

0.279

Low

929775

KCNJ2
Inward rectifier potassium channel 2

1

0

Small-scale

0.249

Low

1233908

EMC5
ER membrane protein complex subunit 5

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024