HitPredict

Interactor 1: PABP1 (P11940)
Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1)
Gene: PABPC1

Interactor 2: MKRN3 (Q13064)
Probable E3 ubiquitin-protein ligase makorin-3 (EC 2.3.2.27) (RING finger protein 63) (RING-type E3 ubiquitin transferase makorin-3) (Zinc finger protein 127)
Gene: MKRN3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.670

Property	Details
Experiments	33744966, 34143182, 32460013
Identification Methods	affinity chromatography technology, pull down, enzymatic study
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:1990904 - ribonucleoprotein complex
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 636 Hs			1 507
+	Hs
		1023561 PABP3_HUMAN (1-636): 0: 541: 91.37		MKRN3_HUMAN (1-507): 0: 599: 100.00
+	Hs
		1023456 PABP4_HUMAN (1-635): 0: 534: 74.69		MKRN3_HUMAN (1-507): 0: 599: 100.00
+	Hs
		516728 PABP1_HUMAN (1-636): 0: 582: 100.00		MKRN1_HUMAN (95-507): 0: 539: 53.61
+	Hs
		1031488 PABP4_HUMAN (1-635): 0: 534: 74.69		MKRN1_HUMAN (95-507): 0: 539: 53.61
+	Hs
		516684 PABP1_HUMAN (1-636): 0: 582: 100.00		MKRN2_HUMAN (94-477): 1.96e-161: 465: 34.88
+	Hs
		1031454 PABP4_HUMAN (1-635): 0: 534: 74.69		MKRN2_HUMAN (94-477): 1.96e-161: 465: 34.88
+	Hs
		1288644 PABP5_HUMAN (6-179): 5.04e-39: 149: 25.26		MKRN1_HUMAN (95-507): 0: 539: 53.61
+	Hs
		1221460 PABP3_HUMAN (1-636): 0: 541: 91.37		ZC3H3_HUMAN (85-220): 2.61e-22: 103: 14.71
+	Hs
		1031384 PABP4_HUMAN (1-635): 0: 534: 74.69		ZC3H3_HUMAN (85-220): 2.61e-22: 103: 14.71
+	Hs
		1288624 PABP5_HUMAN (6-179): 5.04e-39: 149: 25.26		MKRN2_HUMAN (94-477): 1.96e-161: 465: 34.88
+	Dm
		597087 PABP_DROME (2-448): 6.58e-63: 221: 25.21		Q9VP20_DROME (98-450): 1.42e-123: 368: 36.84