HitPredict

Interactor 1: PABP1 (P11940)
Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1)
Gene: PABPC1

Interactor 2: LARP4 (Q71RC2)
La-related protein 4 (La ribonucleoprotein domain family member 4)
Gene: LARP4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29395067
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	La~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0003730 - mRNA 3'-UTR binding GO:0005829 - cytosol GO:0008143 - poly(A) binding GO:0010494 - cytoplasmic stress granule and 1 others more... GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 636 Hs			1 724
+	Hs
		516616 PABP1_HUMAN (1-636): 0: 582: 100.00		LAR4B_HUMAN (9-724): 5.72e-59: 214: 32.70
+	Hs
		1031407 PABP4_HUMAN (1-635): 0: 534: 74.69		LAR4B_HUMAN (9-724): 5.72e-59: 214: 32.70
+	Hs
		516553 PABP1_HUMAN (1-636): 0: 582: 100.00		LAR1B_HUMAN (67-631): 2.76e-36: 148: 16.40
+	Hs
		516541 PABP1_HUMAN (1-636): 0: 582: 100.00		LARP7_HUMAN (123-365): 8.03e-34: 139: 17.22
+	Hs
		516561 PABP1_HUMAN (1-636): 0: 582: 100.00		LARP1_HUMAN (98-620): 1.39e-30: 131: 14.72
+	Hs
		403212 PABP4_HUMAN (1-635): 0: 534: 74.69		LA_HUMAN (119-325): 8.13e-45: 167: 15.66
+	Hs
		1116542 PABP3_HUMAN (1-636): 0: 541: 91.37		LARP7_HUMAN (123-365): 8.03e-34: 139: 17.22
+	Hs
		1031352 PABP4_HUMAN (1-635): 0: 534: 74.69		LARP7_HUMAN (123-365): 8.03e-34: 139: 17.22
+	Hs
		1031367 PABP4_HUMAN (1-635): 0: 534: 74.69		LARP1_HUMAN (98-620): 1.39e-30: 131: 14.72
+	Hs
		516609 PABP1_HUMAN (1-636): 0: 582: 100.00		TITIN_HUMAN (369-718): 1.64e-09: 64: 10.26
+	Hs
		1116304 PAP1L_HUMAN (1-628): 9.51e-166: 489: 68.20		LARP7_HUMAN (123-365): 8.03e-34: 139: 17.22
+	Hs
		1031405 PABP4_HUMAN (1-635): 0: 534: 74.69		TITIN_HUMAN (369-718): 1.64e-09: 64: 10.26
+	Hs
		1174835 PABP5_HUMAN (6-179): 5.04e-39: 149: 25.26		LARP4_HUMAN (1-724): 9.66e-130: 403: 100.00
+	Sc
		376709 PABP_YEAST (2-335): 1.06e-64: 225: 26.71		LHP1_YEAST (92-299): 2.37e-39: 148: 16.60
+	At
		285478 PABP8_ARATH (2-482): 1.38e-62: 221: 24.10		LRP6B_ARATH (51-282): 9.95e-37: 147: 18.35
+	Hs
		1268142 PABP5_HUMAN (6-179): 5.04e-39: 149: 25.26		LAR4B_HUMAN (9-724): 5.72e-59: 214: 32.70
+	Hs
		474033 PAB4L_HUMAN (187-380): 1.23e-36: 142: 29.74		LAR4B_HUMAN (9-724): 5.72e-59: 214: 32.70
+	Dm
		597071 PABP_DROME (2-448): 6.58e-63: 221: 25.21		LARP_DROME (81-223): 5.61e-27: 120: 26.57
+	Hs
		1145698 PABP5_HUMAN (6-179): 5.04e-39: 149: 25.26		LAR1B_HUMAN (67-631): 2.76e-36: 148: 16.40
+	Hs
		1162644 PABP5_HUMAN (6-179): 5.04e-39: 149: 25.26		LARP1_HUMAN (98-620): 1.39e-30: 131: 14.72