Protein: DHB7
3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7 (17-beta-hydroxysteroid dehydrogenase 7) (17-beta-HSD 7) (3-keto-steroid reductase) (EC 1.1.1.270) (Dihydrotestosterone oxidoreductase) (EC 1.1.1.210) (Estradiol 17-beta-dehydrogenase 7) (EC 1.1.1.62) (Short chain dehydrogenase/reductase family 37C member 1)

Gene: DHB7, HSD17B7
Organism: Homo sapiens
Interactions: 33
UniProt ID: P56937

Gene Ontology (top 5):
GO:0000253 - 3-keto sterol reductase activity
GO:0004303 - estradiol 17-beta-dehydrogenase [NAD(P)+] activity
GO:0005789 - endoplasmic reticulum membrane
GO:0006695 - cholesterol biosynthetic process
GO:0006703 - estrogen biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

882179

SLAF1
Signaling lymphocytic activation molecule

3

2

High-throughput

0.609

High

882189

GPAT4
Glycerol-3-phosphate acyltransferase 4

1

2

High-throughput

0.541

High

867960

VMAT1
Chromaffin granule amine transporter

1

3

High-throughput

0.536

High

882190

SPX3
Sugar phosphate exchanger 3

1

1

High-throughput

0.536

High

342529

CAH1
Carbonic anhydrase 1

1

1

High-throughput

0.494

High

882191

BRSK1
Serine/threonine-protein kinase BRSK1

1

3

High-throughput

0.494

High

126577

P2Y10
Putative P2Y purinoceptor 10

1

4

High-throughput

0.489

High

354687

DRA
HLA class II histocompatibility antigen, DR alpha chain

1

3

High-throughput

0.489

High

795944

MAGA8
Melanoma-associated antigen 8

1

3

High-throughput

0.489

High

882176

LCN6
Epididymal-specific lipocalin-6

1

1

High-throughput

0.489

High

882177

VMAT2
Synaptic vesicular amine transporter

1

1

High-throughput

0.489

High

882182

AAAT
Neutral amino acid transporter B(0)

1

1

High-throughput

0.489

High

882184

S39AC
Zinc transporter ZIP12

1

2

High-throughput

0.489

High

882188

SV2A
Synaptic vesicle glycoprotein 2A

1

2

High-throughput

0.489

High

882196

S22A4
Solute carrier family 22 member 4

1

1

High-throughput

0.489

High

882180

ACOX1
Peroxisomal acyl-coenzyme A oxidase 1

1

4

High-throughput

0.470

High

882195

VKOR1
Vitamin K epoxide reductase complex subunit 1

1

0

Small-scale

0.460

High

552363

RFA2
Replication protein A 32 kDa subunit

1

3

High-throughput

0.437

High

650808

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

4

High-throughput

0.437

High

882178

TIF1B
Transcription intermediary factor 1-beta

1

3

High-throughput

0.437

High

882181

RYR3
Ryanodine receptor 3

1

4

High-throughput

0.437

High

882187

TRI67
Tripartite motif-containing protein 67

1

6

High-throughput

0.437

High

882197

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.437

High

353917

IGHM
Immunoglobulin heavy constant mu

1

4

High-throughput

0.407

High

417812

DPOLB
DNA polymerase beta

3

0

High-throughput

0.347

High

532342

PPA5
Tartrate-resistant acid phosphatase type 5

3

0

High-throughput

0.347

High

621202

KTHY
Thymidylate kinase

1

0

High-throughput

0.282

High

882186

GORAB
RAB6-interacting golgin

1

0

High-throughput

0.282

High

882185

TFDP3
Transcription factor Dp family member 3

1

0

High-throughput

0.279

Low

882192

DDI1
Protein DDI1 homolog 1

1

0

High-throughput

0.279

Low

882193

GLMP
Glycosylated lysosomal membrane protein

1

0

High-throughput

0.279

Low

882194

ORAI1
Calcium release-activated calcium channel protein 1

1

0

High-throughput

0.279

Low

882183

E2F4
Transcription factor E2F4

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024