HitPredict

Interactor 1: CALM1 (P0DP29)
Calmodulin-1
Gene: CALM1

Interactor 2: KCNN2 (P70604)
Small conductance calcium-activated potassium channel protein 2 (SK2) (SKCa 2) (SKCa2) (KCa2.2)
Gene: KCNN2

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.866

Property	Details
Experiments	15130477, 11323678, 22579256
Identification Methods	x-ray crystallography, isothermal titration calorimetry, classical fluorescence spectroscopy, cosedimentation in solution
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	CaMBD~EF-hand_7
Common GO terms	GO:0019904 - protein domain specific binding
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 149 Rn			1 580
+	Rn
		116420 CALM1_RAT (1-149): 4.29e-56: 174: 100.00		H6VQ94_RAT (1-557): 0: 552: 99.46
+	Rn
		313190 CALM1_RAT (1-149): 4.29e-56: 174: 100.00		KCNQ2_RAT (55-570): 1.27e-98: 320: 15.04
+	Dm
		880769 CALL_DROME (3-149): 2.69e-57: 177: 66.67		Q5PXF9_DROME (83-453): 2e-83: 279: 16.32
+	Dm
		968528 CALM_DROME (1-149): 1.07e-55: 173: 97.99		Q5PXF9_DROME (83-453): 2e-83: 279: 16.32