HitPredict

Interactor 1: PABP1 (P11940)
Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1)
Gene: PABPC1

Interactor 2: KS6B2 (Q9UBS0)
Ribosomal protein S6 kinase beta-2 (S6K-beta-2) (S6K2) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 2) (P70S6K2) (p70-S6K 2) (S6 kinase-related kinase) (SRK) (Serine/threonine-protein kinase 14B) (p70 ribosomal S6 kinase beta) (S6K-beta) (p70 S6 kinase beta) (p70 S6K-beta) (p70 S6KB) (p70-beta)
Gene: RPS6KB2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30320934
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 636 Hs			1 482
+	Rn
		1144336 PABP1_RAT (1-636): 0: 579: 99.53		AKT3_RAT (6-391): 7.74e-152: 442: 39.59
+	Hs
		516351 PABP1_HUMAN (1-636): 0: 582: 100.00		KAPCA_HUMAN (31-387): 1.3e-144: 419: 34.17
+	Hs
		568649 PABP4_HUMAN (1-635): 0: 534: 74.69		KAPCA_HUMAN (31-387): 1.3e-144: 419: 34.17
+	Hs
		116962 PABP1_HUMAN (1-636): 0: 582: 100.00		SGK1_HUMAN (55-393): 4e-100: 308: 47.03
+	Hs
		582536 NUCL_HUMAN (3-89): 2.56e-19: 94.1: 33.33		KS6B2_HUMAN (1-482): 0: 531: 100.00
+	Mm
		554885 TIA1_MOUSE (4-172): 1.01e-34: 137: 27.51		KPCE_MOUSE (2-395): 5.27e-145: 434: 33.74
+	Hs
		582149 NUCL_HUMAN (3-89): 2.56e-19: 94.1: 33.33		KS6A3_HUMAN (5-380): 2.45e-105: 331: 26.85