Interactor 1: PCNA (P12004)
Proliferating cell nuclear antigen (PCNA) (Cyclin)
Gene: PCNA

Interactor 2: DPOD1 (P28340)
DNA polymerase delta catalytic subunit (EC 2.7.7.7) (3'-5' exodeoxyribonuclease) (EC 3.1.11.-) (DNA polymerase subunit delta p125)
Gene: POLD1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.974

The method score is based on:

Property Details
Experiments 12403614, 16510448, 26496610, 12171929, 15805117, 14988403, 20227374, 11328591, 24768535, 24958773
Identification Methods affinity chromatography technology, far western blotting, pull down, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains DNA_pol_B~PCNA_N, PCNA_N~zf-C4pol
Common GO terms GO:0003682 - chromatin binding
GO:0003684 - damaged DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006287 - base-excision repair, gap-filling
and 2 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 261
Hs

1 1107
+ Mm
+ At
+ Dm
+ Sp
+ Sc
+ Ss
+ Hs
+ Dm
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024