Protein: CERK1
Ceramide kinase (hCERK) (EC 2.7.1.138) (Acylsphingosine kinase) (Lipid kinase 4) (LK4)

Gene: CERK1, CERK
Organism: Homo sapiens
Interactions: 92
UniProt ID: Q8TCT0

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0001729 - ceramide kinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1057688

TNR9
Tumor necrosis factor receptor superfamily member 9

3

2

High-throughput

0.667

High

1328646

KCD17
BTB/POZ domain-containing protein KCTD17

3

1

High-throughput

0.667

High

332552

CCDB1
Cyclin-D1-binding protein 1

3

0

High-throughput

0.638

High

1277330

NT2NA
Notch homolog 2 N-terminal-like protein A

2

2

High-throughput

0.633

High

1349968

VWCE
von Willebrand factor C and EGF domain-containing protein

2

1

High-throughput

0.628

High

284339

GEMI
Geminin

2

0

High-throughput

0.602

High

1029620

CD83
CD83 antigen

2

0

High-throughput

0.602

High

1349964

HAVR2
Hepatitis A virus cellular receptor 2

2

0

High-throughput

0.602

High

1349969

MRAP2
Melanocortin-2 receptor accessory protein 2

2

0

High-throughput

0.602

High

1349986

I20RA
Interleukin-20 receptor subunit alpha

2

0

High-throughput

0.602

High

190443

COPT1
High affinity copper uptake protein 1

2

0

High-throughput

0.576

High

1205900

MTUS2
Microtubule-associated tumor suppressor candidate 2

1

3

High-throughput

0.573

High

1059700

KRA11
Keratin-associated protein 1-1

2

3

High-throughput

0.553

High

1311447

TRI42
Tripartite motif-containing protein 42

2

2

High-throughput

0.553

High

1349973

KRA92
Keratin-associated protein 9-2

2

2

High-throughput

0.553

High

1349974

KRA32
Keratin-associated protein 3-2

2

1

High-throughput

0.553

High

1349975

KRA31
Keratin-associated protein 3-1

2

1

High-throughput

0.553

High

1349979

PKHF2
Pleckstrin homology domain-containing family F member 2

2

2

High-throughput

0.553

High

404252

GCR
Glucocorticoid receptor

1

2

High-throughput

0.536

High

659539

CRCM
Colorectal mutant cancer protein

1

1

High-throughput

0.536

High

932916

P5CS
Delta-1-pyrroline-5-carboxylate synthase

1

1

High-throughput

0.536

High

1157154

PDCD2
Programmed cell death protein 2

1

1

High-throughput

0.536

High

1349966

CELF1
CUGBP Elav-like family member 1

1

1

High-throughput

0.536

High

1349970

ANM1
Protein arginine N-methyltransferase 1

1

1

High-throughput

0.536

High

1349972

DDX23
Probable ATP-dependent RNA helicase DDX23

1

1

High-throughput

0.536

High

1349976

ILKAP
Integrin-linked kinase-associated serine/threonine phosphatase 2C

1

2

High-throughput

0.536

High

1349985

TR10D
Tumor necrosis factor receptor superfamily member 10D

1

2

High-throughput

0.536

High

560890

HEM1
5-aminolevulinate synthase, non-specific, mitochondrial

1

1

High-throughput

0.523

High

972492

RS14
Small ribosomal subunit protein uS11

1

1

High-throughput

0.515

High

251788

BUB1B
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta

1

0

High-throughput

0.513

High

543244

UBL4A
Ubiquitin-like protein 4A

1

0

High-throughput

0.513

High

626970

FST
Follistatin

1

0

High-throughput

0.513

High

856826

BAG6
Large proline-rich protein BAG6

1

0

High-throughput

0.513

High

1007885

X3CL1
Fractalkine

1

0

High-throughput

0.513

High

1022431

IDD
Integral membrane protein DGCR2/IDD

1

0

High-throughput

0.513

High

1066720

NCBP1
Nuclear cap-binding protein subunit 1

1

0

High-throughput

0.513

High

1095149

RED
Protein Red

1

0

High-throughput

0.513

High

1127742

HLTF
Helicase-like transcription factor

1

0

High-throughput

0.513

High

1216386

FAXC
Failed axon connections homolog

1

0

High-throughput

0.513

High

1287079

ALPK2
Alpha-protein kinase 2

1

0

High-throughput

0.513

High

1308269

HDBP1
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1

1

0

High-throughput

0.513

High

1334477

RN149
E3 ubiquitin-protein ligase RNF149

1

0

High-throughput

0.513

High

1339383

GP156
Probable G-protein coupled receptor 156

1

0

High-throughput

0.513

High

1349971

APOL2
Apolipoprotein L2

1

0

High-throughput

0.513

High

1349977

TTYH1
Protein tweety homolog 1

1

0

High-throughput

0.513

High

1349981

4ET
Eukaryotic translation initiation factor 4E transporter

1

0

High-throughput

0.513

High

1349982

RPRM
Protein reprimo

1

0

High-throughput

0.513

High

1349983

RAD18
E3 ubiquitin-protein ligase RAD18

1

0

High-throughput

0.513

High

1349988

SPG7
Mitochondrial inner membrane m-AAA protease component paraplegin

1

0

High-throughput

0.513

High

1349990

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

0

High-throughput

0.513

High

422684

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.501

High

209305

PRP4
U4/U6 small nuclear ribonucleoprotein Prp4

1

1

High-throughput

0.489

High

685653

U2AF2
Splicing factor U2AF 65 kDa subunit

1

1

High-throughput

0.489

High

1141397

WDR43
WD repeat-containing protein 43

1

1

High-throughput

0.489

High

1214650

RBM26
RNA-binding protein 26

1

1

High-throughput

0.489

High

1349967

UTP4
U3 small nucleolar RNA-associated protein 4 homolog

1

1

High-throughput

0.489

High

587

NBPFJ
NBPF family member NBPF19

1

2

High-throughput

0.481

High

412301

NTRK1
High affinity nerve growth factor receptor

1

1

High-throughput

0.479

High

1270911

RHOU
Rho-related GTP-binding protein RhoU

1

1

High-throughput

0.479

High

1349978

RHOJ
Rho-related GTP-binding protein RhoJ

1

1

High-throughput

0.479

High

517071

NT2NC
Notch homolog 2 N-terminal-like protein C

1

2

High-throughput

0.470

High

978183

RHOB
Rho-related GTP-binding protein RhoB

1

0

High-throughput

0.458

High

949949

KR103
Keratin-associated protein 10-3

1

3

High-throughput

0.439

High

174567

TRI66
Tripartite motif-containing protein 66

1

1

High-throughput

0.437

High

182335

WDR46
WD repeat-containing protein 46

1

2

High-throughput

0.437

High

388437

B3AT
Band 3 anion transport protein

1

0

High-throughput

0.426

High

3014

A0A0G2JJL1
WD repeat domain 46

1

2

High-throughput

0.407

High

1326967

SVOP
Synaptic vesicle 2-related protein

1

2

High-throughput

0.407

High

71395

HECA2
HEPACAM family member 2

3

0

High-throughput

0.347

High

1340733

TPC2
Two pore channel protein 2

2

0

High-throughput

0.328

High

70378

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.316

High

217162

MS18B
Protein Mis18-beta

2

0

High-throughput

0.316

High

300439

KRT34
Keratin, type I cuticular Ha4

2

0

High-throughput

0.316

High

437467

CRBA1
Beta-crystallin A3 [Cleaved into: Beta-crystallin A3, isoform A1, Delta4 form; Beta-crystallin A3, isoform A1, Delta7 form; Beta-crystallin A3, isoform A1, Delta8 form]

2

0

High-throughput

0.316

High

506788

NHLC4
NHL-repeat-containing protein 4

2

0

High-throughput

0.316

High

1186670

KRA62
Keratin-associated protein 6-2

2

0

High-throughput

0.316

High

1186840

KR196
Keratin-associated protein 19-6

2

0

High-throughput

0.316

High

1307003

KR191
Keratin-associated protein 19-1

2

0

High-throughput

0.316

High

1307044

KR111
Keratin-associated protein 11-1

2

0

High-throughput

0.316

High

167106

GEMI2
Gem-associated protein 2

1

0

High-throughput

0.279

Low

317200

UBP1
Ubiquitin carboxyl-terminal hydrolase 1

1

0

High-throughput

0.279

Low

1144093

TEBP
Prostaglandin E synthase 3

1

0

High-throughput

0.279

Low

1149811

TAF13
Transcription initiation factor TFIID subunit 13

1

0

High-throughput

0.279

Low

1206498

PRC2B
Protein PRRC2B

1

0

High-throughput

0.279

Low

1213126

BEND3
BEN domain-containing protein 3

1

0

High-throughput

0.279

Low

1233829

CV042
Uncharacterized protein C22orf42

1

0

High-throughput

0.279

Low

1244777

CC174
Coiled-coil domain-containing protein 174

1

0

High-throughput

0.279

Low

1349965

TB22A
TBC1 domain family member 22A

1

0

High-throughput

0.279

Low

1349980

UD17
UDP-glucuronosyltransferase 1A7

1

0

High-throughput

0.279

Low

1349987

AT7L1
Ataxin-7-like protein 1

1

0

High-throughput

0.279

Low

1349989

NOP16
Nucleolar protein 16

1

0

High-throughput

0.269

Low

1349984

F120C
Constitutive coactivator of PPAR-gamma-like protein 2

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025