HitPredict

Interactor 1: K2C3 (P12035)
Keratin, type II cytoskeletal 3 (65 kDa cytokeratin) (Cytokeratin-3) (CK-3) (Keratin-3) (K3) (Type-II keratin Kb3)
Gene: KRT3

Interactor 2: CBL (P22681)
E3 ubiquitin-protein ligase CBL (EC 2.3.2.27) (Casitas B-lineage lymphoma proto-oncogene) (Proto-oncogene c-Cbl) (RING finger protein 55) (RING-type E3 ubiquitin transferase CBL) (Signal transduction protein CBL)
Gene: CBL

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19380743
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 628 Hs			1 906
+	Hs
		610265 K22E_HUMAN (170-516): 5.85e-174: 510: 72.49		CBL_HUMAN (1-906): 0: 917: 100.00
+	Hs
		380560 K2C1_HUMAN (163-531): 1.13e-105: 334: 73.44		CBL_HUMAN (1-906): 0: 917: 100.00
+	Hs
		610513 KRT84_HUMAN (3-623): 3.25e-96: 309: 42.54		CBL_HUMAN (1-906): 0: 917: 100.00
+	Hs
		610433 K2C79_HUMAN (55-587): 6.87e-80: 264: 56.55		CBL_HUMAN (1-906): 0: 917: 100.00
+	Hs
		380445 K2C6B_HUMAN (36-537): 5.85e-76: 254: 64.54		CBL_HUMAN (1-906): 0: 917: 100.00
+	Hs
		610295 K2C6C_HUMAN (36-537): 2.14e-75: 253: 63.94		CBL_HUMAN (1-906): 0: 917: 100.00
+	Hs
		531534 K2C5_HUMAN (36-516): 4.1e-74: 250: 63.79		CBL_HUMAN (1-906): 0: 917: 100.00
+	Hs
		359466 K2C6A_HUMAN (36-537): 5.94e-73: 246: 64.74		CBL_HUMAN (1-906): 0: 917: 100.00
+	Hs
		203197 K2C8_HUMAN (170-550): 6.7e-164: 479: 65.35		SYNJ1_HUMAN (542-897): 2.72e-14: 79.6: 10.22
+	Hs
		409194 K2C8_HUMAN (170-550): 6.7e-164: 479: 65.35		ASPP1_HUMAN (445-844): 1.47e-10: 67.3: 10.25
+	Hs
		580149 K2C4_HUMAN (71-532): 8.33e-66: 226: 64.74		ASPP1_HUMAN (445-844): 1.47e-10: 67.3: 10.25