Interactor 1: HARS1 (P12081)
Histidine--tRNA ligase, cytoplasmic (EC 6.1.1.21) (Histidyl-tRNA synthetase) (HisRS)
Gene: HARS1
Interactor 2: HARS1 (P12081)
Histidine--tRNA ligase, cytoplasmic (EC 6.1.1.21) (Histidyl-tRNA synthetase) (HisRS)
Gene: HARS1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.47 | 1.00 | 0.692 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 22958643 |
| Identification Methods | molecular sieving, x-ray crystallography |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | HGTP_anticodon~HGTP_anticodon, HGTP_anticodon~tRNA-synt_His, tRNA-synt_His~tRNA-synt_His, WHEP-TRS~tRNA-synt_His |
| Common GO terms | GO:0003723 - RNA binding GO:0004821 - histidine-tRNA ligase activity GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005739 - mitochondrion and 6 others more... |
| Homologous interactions | 13 |
Homologous interactions
Color coding for hit scores 
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| + | Ec | |
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
