Protein: HRB1
Serine/arginine (SR)-type shuttling mRNA binding protein HRB1 (Hypothetical RNA-binding protein 1) (Polyadenylate-binding protein HRB1) (Protein TOM34)

Gene: HRB1
Organism: Saccharomyces cerevisiae S288C
Interactions: 102
UniProt ID: P38922

Gene Ontology (top 5):
GO:0000932 - P-body
GO:0003682 - chromatin binding
GO:0003723 - RNA binding
GO:0003729 - mRNA binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

807692

CTK1
CTD kinase subunit alpha

3

6

Small-scale

0.867

High

807702

YRA1
RNA annealing protein YRA1

3

18

Small-scale

0.827

High

656962

BUR1
Serine/threonine-protein kinase BUR1

2

7

High-throughput

0.802

High

807691

SKY1
Serine/threonine-protein kinase SKY1

2

20

Small-scale

0.799

High

676726

GBP2
Serine/arginine

2

18

Small-scale

0.754

High

735260

KNS1
Dual specificity protein kinase KNS1

1

14

High-throughput

0.691

High

807678

CLA4
Serine/threonine-protein kinase CLA4

1

3

High-throughput

0.691

High

807683

THO2
THO complex subunit 2

4

5

Small-scale

0.691

High

523932

HSP71
Heat shock protein SSA1

4

5

High-throughput

0.683

High

753236

MFT1
THO complex subunit MFT1

5

1

Small-scale

0.650

High

605897

HPR1
THO complex subunit HPR1

4

1

Small-scale

0.636

High

392723

HSP82
ATP-dependent molecular chaperone HSP82

3

3

High-throughput

0.633

High

150167

THP2
THO complex subunit THP2

4

1

Small-scale

0.630

High

403509

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

19

Small-scale

0.618

High

410128

RL25
Large ribosomal subunit protein uL23

1

4

High-throughput

0.618

High

740914

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

20

High-throughput

0.618

High

757484

NCBP1
Nuclear cap-binding protein complex subunit 1

1

5

Small-scale

0.618

High

807687

NOP3
Serine/arginine

1

20

Small-scale

0.618

High

807698

NCBP2
Nuclear cap-binding protein subunit 2

1

15

High-throughput

0.618

High

807704

MTR10
mRNA transport regulator MTR10

1

5

Small-scale

0.618

High

807684

TEX1
Protein TEX1

2

4

Small-scale

0.601

High

807705

MEX67
mRNA export factor MEX67

2

4

Small-scale

0.584

High

432579

RL7A
Large ribosomal subunit protein uL30A

1

5

High-throughput

0.575

High

435089

RS3
Small ribosomal subunit protein uS3

1

2

High-throughput

0.575

High

747357

RSSA1
Small ribosomal subunit protein uS2A

2

2

High-throughput

0.571

High

792043

GBLP
Small ribosomal subunit protein RACK1

2

6

High-throughput

0.571

High

454444

PHO4
Phosphate system positive regulatory protein PHO4

1

1

High-throughput

0.536

High

526679

HSP72
Heat shock protein SSA2

1

5

High-throughput

0.536

High

544853

SSB1
Ribosome-associated molecular chaperone SSB1

1

6

High-throughput

0.536

High

807670

AIR1
Protein AIR1

1

8

High-throughput

0.536

High

744297

CHD1
Chromo domain-containing protein 1

1

10

High-throughput

0.515

High

792801

ANM1
Protein arginine N-methyltransferase 1

1

7

Small-scale

0.501

High

807682

H1
Histone H1

1

0

High-throughput

0.493

High

367022

ATPB
ATP synthase subunit beta, mitochondrial

1

2

High-throughput

0.489

High

149760

RS9A
Small ribosomal subunit protein uS4A

1

2

High-throughput

0.479

High

433638

RL26A
Large ribosomal subunit protein uL24A

1

2

High-throughput

0.479

High

435962

RS13
Small ribosomal subunit protein uS15

1

2

High-throughput

0.479

High

438689

SC160
Protein SCP160

1

20

High-throughput

0.479

High

453945

IF4E
Eukaryotic translation initiation factor 4E

1

4

Small-scale

0.479

High

455061

RS19A
Small ribosomal subunit protein eS19A

1

1

High-throughput

0.479

High

512075

RS4A
Small ribosomal subunit protein eS4A

1

2

High-throughput

0.479

High

514637

RS18A
Small ribosomal subunit protein uS13A

1

1

High-throughput

0.479

High

594364

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

1

High-throughput

0.479

High

645409

XRN1
5'-3' exoribonuclease 1

1

4

Small-scale

0.479

High

674621

RS2
Small ribosomal subunit protein uS5

1

2

High-throughput

0.479

High

677394

KRR1
KRR1 small subunit processome component

1

3

High-throughput

0.479

High

679669

CDC48
Cell division control protein 48

1

5

High-throughput

0.479

High

707079

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

721612

RENT1
ATP-dependent helicase NAM7

1

15

Small-scale

0.479

High

778326

RS27A
Small ribosomal subunit protein eS27A

1

1

High-throughput

0.479

High

790359

STT4
Phosphatidylinositol 4-kinase STT4

1

1

High-throughput

0.479

High

802171

RS20
Small ribosomal subunit protein uS10

1

3

High-throughput

0.479

High

807665

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

15

Small-scale

0.479

High

807669

MLP2
Protein MLP2

1

9

High-throughput

0.479

High

807672

PRP17
Pre-mRNA-processing factor 17

1

4

Small-scale

0.479

High

807676

MTR4
ATP-dependent RNA helicase DOB1

1

13

Small-scale

0.479

High

807679

RS12
Small ribosomal subunit protein eS12

1

1

High-throughput

0.479

High

807680

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

3

Small-scale

0.479

High

807681

EIF2A
Eukaryotic translation initiation factor 2A

1

4

High-throughput

0.479

High

807688

RS15
Small ribosomal subunit protein uS19

1

2

High-throughput

0.479

High

807689

MLP1
Protein MLP1

1

9

Small-scale

0.479

High

807693

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.479

High

807696

SUB2
ATP-dependent RNA helicase SUB2

1

17

Small-scale

0.479

High

807697

RS10A
Small ribosomal subunit protein eS10A

1

1

High-throughput

0.479

High

807699

TMA46
Translation machinery-associated protein 46

1

1

High-throughput

0.479

High

807700

RRP6
Exosome complex exonuclease RRP6

1

1

Small-scale

0.479

High

807703

DCP1
mRNA-decapping enzyme subunit 1

1

1

Small-scale

0.479

High

807667

RPN3
26S proteasome regulatory subunit RPN3

1

1

High-throughput

0.470

High

453024

CBP8
Cytochrome B pre-mRNA-processing protein 1

1

0

High-throughput

0.458

High

678501

YIH1
Protein IMPACT homolog

1

0

High-throughput

0.458

High

734977

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

747849

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

804838

NMD2
Nonsense-mediated mRNA decay protein 2

1

0

Small-scale

0.458

High

807671

CSN11
Cop9 signalosome complex subunit 11

1

0

High-throughput

0.458

High

807674

YPP1
Cargo-transport protein YPP1

1

0

High-throughput

0.458

High

807677

UPF3
Nonsense-mediated mRNA decay protein 3

1

0

Small-scale

0.458

High

807695

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.458

High

807701

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

386704

TBB
Tubulin beta chain

1

2

High-throughput

0.445

High

481622

HSP73
Heat shock protein SSA3

1

5

High-throughput

0.445

High

486171

TBA1
Tubulin alpha-1 chain

1

1

High-throughput

0.445

High

670697

SIS1
Protein SIS1

1

2

High-throughput

0.445

High

727022

HS104
Heat shock protein 104

1

1

High-throughput

0.445

High

741569

HSP7F
Heat shock protein homolog SSE1

1

6

High-throughput

0.445

High

804158

SSZ1
Ribosome-associated complex subunit SSZ1

1

3

High-throughput

0.445

High

807666

HSP7E
Heat shock protein SSC3, mitochondrial

1

4

High-throughput

0.445

High

807668

SSB2
Ribosome-associated molecular chaperone SSB2

1

6

High-throughput

0.445

High

807673

RL10
Large ribosomal subunit protein uL16

1

1

High-throughput

0.445

High

383699

RS17A
Small ribosomal subunit protein eS17A

1

1

High-throughput

0.437

High

503041

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.437

High

504210

RL31A
Large ribosomal subunit protein eL31A

1

2

High-throughput

0.437

High

513007

RS8A
Small ribosomal subunit protein eS8A

1

1

High-throughput

0.437

High

689453

RS7A
Small ribosomal subunit protein eS7A

1

1

High-throughput

0.437

High

807664

LAA1
AP-1 accessory protein LAA1

1

2

High-throughput

0.437

High

427276

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.426

High

653856

HSP12
12 kDa heat shock protein

1

0

High-throughput

0.426

High

807675

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.426

High

807685

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.426

High

807686

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.426

High

807690

LGE1
Transcriptional regulatory protein LGE1

1

0

High-throughput

0.426

High

807694

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

2

High-throughput

0.407

High

798526

BIT2
Probable target of rapamycin complex 2 subunit BIT2

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025