HitPredict

Interactor 1: CO6A1 (P12109)
Collagen alpha-1(VI) chain
Gene: COL6A1

Interactor 2: PLOD1 (Q02809)
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 (EC 1.14.11.4) (Lysyl hydroxylase 1) (LH1)
Gene: PLOD1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1028 Hs			1 727
+	Hs
		237019 CO6A1_HUMAN (15-1028): 0: 731: 100.00		PLOD3_HUMAN (21-727): 0: 1195: 59.38
+	Hs
		68474 A8MWQ5_HUMAN (353-593): 6.96e-37: 150: 32.09		PLOD1_HUMAN (1-727): 0: 1245: 100.00
+	Hs
		972810 COPA1_HUMAN (379-617): 7.1e-31: 132: 35.43		PLOD1_HUMAN (1-727): 0: 1245: 100.00
+	Hs
		972805 COLA1_HUMAN (608-835): 3.31e-20: 99.1: 24.68		PLOD1_HUMAN (1-727): 0: 1245: 100.00
+	Hs
		358604 CO2A1_HUMAN (275-591): 3.43e-19: 95.9: 37.73		PLOD1_HUMAN (1-727): 0: 1245: 100.00
+	Hs
		358661 CO4A1_HUMAN (224-591): 9.94e-18: 91.4: 34.58		PLOD1_HUMAN (1-727): 0: 1245: 100.00
+	Hs
		441060 CO4A2_HUMAN (345-637): 2.46e-17: 89.8: 30.82		PLOD1_HUMAN (1-727): 0: 1245: 100.00
+	Hs
		129937 COLA1_HUMAN (608-835): 3.31e-20: 99.1: 24.68		PLOD2_HUMAN (13-727): 0: 1209: 60.06
+	Hs
		237111 COLA1_HUMAN (608-835): 3.31e-20: 99.1: 24.68		PLOD3_HUMAN (21-727): 0: 1195: 59.38
+	Hs
		237006 CO4A1_HUMAN (224-591): 9.94e-18: 91.4: 34.58		PLOD3_HUMAN (21-727): 0: 1195: 59.38
+	Hs
		237016 CO4A2_HUMAN (345-637): 2.46e-17: 89.8: 30.82		PLOD3_HUMAN (21-727): 0: 1195: 59.38
+	Hs
		237054 CO9A2_HUMAN (352-592): 6.43e-14: 78.2: 34.99		PLOD3_HUMAN (21-727): 0: 1195: 59.38
+	Hs
		237052 CO4A6_HUMAN (360-636): 5.4e-13: 75.9: 32.85		PLOD3_HUMAN (21-727): 0: 1195: 59.38
+	Dm
		435988 CO4A1_DROME (143-488): 9.74e-34: 143: 30.06		PLOD_DROME (15-727): 0: 1029: 43.75
+	Hs
		517960 CO6A1_HUMAN (15-1028): 0: 731: 100.00		GT252_HUMAN (266-535): 7.41e-95: 309: 25.48
+	Hs
		1223326 COLA1_HUMAN (608-835): 3.31e-20: 99.1: 24.68		GT252_HUMAN (266-535): 7.41e-95: 309: 25.48
+	Hs
		358613 CO2A1_HUMAN (275-591): 3.43e-19: 95.9: 37.73		GT252_HUMAN (266-535): 7.41e-95: 309: 25.48
+	Hs
		358664 CO4A1_HUMAN (224-591): 9.94e-18: 91.4: 34.58		GT252_HUMAN (266-535): 7.41e-95: 309: 25.48
+	Hs
		441073 CO4A2_HUMAN (345-637): 2.46e-17: 89.8: 30.82		GT252_HUMAN (266-535): 7.41e-95: 309: 25.48
+	Hs
		1047997 CO9A2_HUMAN (352-592): 6.43e-14: 78.2: 34.99		GT252_HUMAN (266-535): 7.41e-95: 309: 25.48