HitPredict

Interactor 1: TPR (P12270)
Nucleoprotein TPR (Megator) (NPC-associated intranuclear protein) (Translocated promoter region protein)
Gene: TPR

Interactor 2: LZTS2 (Q9BRK4)
Leucine zipper putative tumor suppressor 2 (hLZTS2) (Protein LAPSER1)
Gene: LZTS2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 2363 Hs			1 669
+	Hs
		148338 TPR_HUMAN (1-2351): 7.93e-175: 597: 100.00		CTRO_HUMAN (327-578): 7.02e-09: 61.3: 16.36
+	Hs
		1310111 CP250_HUMAN (190-2334): 9.64e-69: 260: 10.18		LZTS2_HUMAN (1-669): 6.28e-56: 203: 100.00
+	Hs
		166775 CE290_HUMAN (3-2065): 8.45e-54: 211: 10.70		LZTS2_HUMAN (1-669): 6.28e-56: 203: 100.00
+	Hs
		1145917 CP250_HUMAN (190-2334): 9.64e-69: 260: 10.18		CP135_HUMAN (300-610): 1.6e-09: 63.5: 21.52
+	Hs
		166706 CE290_HUMAN (3-2065): 8.45e-54: 211: 10.70		DCTN1_HUMAN (88-572): 2.4e-12: 72.7: 10.41
+	Hs
		166727 CE290_HUMAN (3-2065): 8.45e-54: 211: 10.70		CP135_HUMAN (300-610): 1.6e-09: 63.5: 21.52
+	Hs
		148534 CENPF_HUMAN (270-2309): 1.3e-43: 178: 10.34		CTRO_HUMAN (327-578): 7.02e-09: 61.3: 16.36
+	Hs
		522657 MYH7_HUMAN (1098-2165): 1.22e-38: 161: 10.38		MYH4_HUMAN (261-669): 1.55e-12: 73.1: 12.32
+	Rn
		361106 MYH6_RAT (1071-2238): 1.06e-36: 155: 8.98		MYH6_RAT (324-644): 1.04e-11: 70.5: 15.01
+	Hs
		522585 MYH7_HUMAN (1098-2165): 1.22e-38: 161: 10.38		MYH7_HUMAN (140-540): 9.01e-09: 61.2: 9.45
+	Hs
		528435 MYH8_HUMAN (1310-2333): 3.23e-33: 144: 10.47		MYH4_HUMAN (261-669): 1.55e-12: 73.1: 12.32
+	Hs
		502901 MYH6_HUMAN (1310-2320): 5.95e-32: 139: 10.02		MYH3_HUMAN (321-655): 9.39e-13: 74: 14.93
+	Hs
		528432 MYH13_HUMAN (1098-2165): 8.48e-35: 149: 10.63		MYH8_HUMAN (196-572): 6.41e-09: 61.6: 9.26
+	Mm
		93570 MYH9_MOUSE (1370-2342): 2.48e-31: 137: 10.58		DESP_MOUSE (337-641): 2.9e-11: 69.3: 18.65
+	Hs
		528356 MYH6_HUMAN (1310-2320): 5.95e-32: 139: 10.02		MYH6_HUMAN (140-554): 2.32e-09: 63.1: 9.14
+	Hs
		148466 MYH11_HUMAN (1381-2328): 1.43e-31: 138: 9.26		CTRO_HUMAN (327-578): 7.02e-09: 61.3: 16.36
+	Hs
		725097 MYH11_HUMAN (1381-2328): 1.43e-31: 138: 9.26		MYH10_HUMAN (321-640): 8.77e-09: 61.2: 18.79
+	Hs
		148460 MYH9_HUMAN (1404-2309): 4.5e-28: 127: 9.29		CTRO_HUMAN (327-578): 7.02e-09: 61.3: 16.36
+	Hs
		724687 MYH9_HUMAN (1404-2309): 4.5e-28: 127: 9.29		MYH10_HUMAN (321-640): 8.77e-09: 61.2: 18.79