Protein: CCL3
C-C motif chemokine 3 (G0/G1 switch regulatory protein 19-1) (Macrophage inflammatory protein 1-alpha) (MIP-1-alpha) (PAT 464.1) (SIS-beta) (Small-inducible cytokine A3) (Tonsillar lymphocyte LD78 alpha protein) [Cleaved into: MIP-1-alpha(4-69) (LD78-alpha(4-69))]

Gene: CCL3
Organism: Homo sapiens
Interactions: 179
UniProt ID: P10147

Gene Ontology (top 5):
GO:0000165 - MAPK cascade
GO:0001649 - osteoblast differentiation
GO:0001775 - cell activation
GO:0002548 - monocyte chemotaxis
GO:0004672 - protein kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

518812

CCR1
C-C chemokine receptor type 1

13

20

Small-scale

0.972

High

518822

CCR5
C-C chemokine receptor type 5

6

20

Small-scale

0.933

High

518796

CCL3
C-C motif chemokine 3

2

19

Small-scale

0.812

High

518813

CXCR5
C-X-C chemokine receptor type 5

2

20

Small-scale

0.754

High

518800

CSPG2
Versican core protein

1

10

High-throughput

0.691

High

518896

HPLN3
Hyaluronan and proteoglycan link protein 3

1

11

High-throughput

0.691

High

518821

CCR4
C-C chemokine receptor type 4

1

20

Small-scale

0.647

High

141810

ACKR2
Atypical chemokine receptor 2

1

20

Small-scale

0.618

High

518798

CCL4
C-C motif chemokine 4

1

20

Small-scale

0.618

High

518820

CCR3
C-C chemokine receptor type 3

1

20

Small-scale

0.618

High

518926

UBQL2
Ubiquilin-2

2

5

High-throughput

0.606

High

518934

UBQL1
Ubiquilin-1

2

5

High-throughput

0.606

High

518801

IDE
Insulin-degrading enzyme

1

4

Small-scale

0.568

High

133160

QSOX1
Sulfhydryl oxidase 1

1

2

High-throughput

0.536

High

136793

AGRIN
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment

1

11

High-throughput

0.536

High

183220

LAMA5
Laminin subunit alpha-5

1

10

High-throughput

0.536

High

215700

COCH
Cochlin

1

3

High-throughput

0.536

High

229863

EDIL3
EGF-like repeat and discoidin I-like domain-containing protein 3

1

9

High-throughput

0.536

High

249028

NRP2
Neuropilin-2

1

5

High-throughput

0.536

High

251064

B4GT3
Beta-1,4-galactosyltransferase 3

1

5

High-throughput

0.536

High

251137

B4GT4
Beta-1,4-galactosyltransferase 4

1

5

High-throughput

0.536

High

261588

CATL2
Cathepsin L2

1

1

High-throughput

0.536

High

317546

SLIT2
Slit homolog 2 protein

1

4

High-throughput

0.536

High

335374

GDF11
Growth/differentiation factor 11

1

3

High-throughput

0.536

High

337246

ATS2
A disintegrin and metalloproteinase with thrombospondin motifs 2

1

4

High-throughput

0.536

High

337524

LARG1
Xylosyl- and glucuronyltransferase LARGE1

1

1

High-throughput

0.536

High

340697

NET1
Netrin-1

1

7

High-throughput

0.536

High

348041

M4K4
Mitogen-activated protein kinase kinase kinase kinase 4

1

2

High-throughput

0.536

High

450164

GDN
Glia-derived nexin

1

1

High-throughput

0.536

High

462835

LAMB1
Laminin subunit beta-1

1

8

High-throughput

0.536

High

518797

LAMC1
Laminin subunit gamma-1

1

7

High-throughput

0.536

High

518799

BMP1
Bone morphogenetic protein 1

1

3

High-throughput

0.536

High

518802

B4GT1
Beta-1,4-galactosyltransferase 1

1

5

High-throughput

0.536

High

518803

ARSB
Arylsulfatase B

1

5

High-throughput

0.536

High

518806

VGFR1
Vascular endothelial growth factor receptor 1

1

3

High-throughput

0.536

High

518809

LAMA1
Laminin subunit alpha-1

1

8

High-throughput

0.536

High

518814

GALNS
N-acetylgalactosamine-6-sulfatase

1

5

High-throughput

0.536

High

518815

TIMP3
Metalloproteinase inhibitor 3

1

2

High-throughput

0.536

High

518816

PEDF
Pigment epithelium-derived factor

1

1

High-throughput

0.536

High

518818

COIA1
Collagen alpha-1(XVIII) chain [Cleaved into: Endostatin; Non-collagenous domain 1

1

4

High-throughput

0.536

High

518819

MMP15
Matrix metalloproteinase-15

1

5

High-throughput

0.536

High

518823

NDST1
Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1

1

2

High-throughput

0.536

High

518826

LAMB2
Laminin subunit beta-2

1

8

High-throughput

0.536

High

518827

NETR
Neurotrypsin

1

1

High-throughput

0.536

High

518828

INHBE
Inhibin beta E chain

1

3

High-throughput

0.536

High

518831

CNTP1
Contactin-associated protein 1

1

14

High-throughput

0.536

High

518836

MFGM
Lactadherin

1

4

High-throughput

0.536

High

518838

GALT2
Polypeptide N-acetylgalactosaminyltransferase 2

1

4

High-throughput

0.536

High

518841

MAP7
Ensconsin

1

2

High-throughput

0.536

High

518844

ICAM4
Intercellular adhesion molecule 4

1

2

High-throughput

0.536

High

518845

PGFRL
Platelet-derived growth factor receptor-like protein

1

3

High-throughput

0.536

High

518847

LAMA4
Laminin subunit alpha-4

1

12

High-throughput

0.536

High

518850

LRC24
Leucine-rich repeat-containing protein 24

1

4

High-throughput

0.536

High

518852

DNLZ
DNL-type zinc finger protein

1

1

High-throughput

0.536

High

518856

METRL
Meteorin-like protein

1

1

High-throughput

0.536

High

518861

LARP4
La-related protein 4

1

1

High-throughput

0.536

High

518866

CHSS1
Chondroitin sulfate synthase 1

1

7

High-throughput

0.536

High

518868

CILP2
Cartilage intermediate layer protein 2

1

6

High-throughput

0.536

High

518870

SULF2
Extracellular sulfatase Sulf-2

1

5

High-throughput

0.536

High

518871

SULF1
Extracellular sulfatase Sulf-1

1

5

High-throughput

0.536

High

518879

NDNF
Protein NDNF

1

1

High-throughput

0.536

High

518880

ATS17
A disintegrin and metalloproteinase with thrombospondin motifs 17

1

4

High-throughput

0.536

High

518881

ATS15
A disintegrin and metalloproteinase with thrombospondin motifs 15

1

4

High-throughput

0.536

High

518884

LAR4B
La-related protein 4B

1

1

High-throughput

0.536

High

518886

PCSK5
Proprotein convertase subtilisin/kexin type 5

1

2

High-throughput

0.536

High

518889

TRI11
E3 ubiquitin-protein ligase TRIM11

1

1

High-throughput

0.536

High

518890

LIGO1
Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1

1

3

High-throughput

0.536

High

518895

MED15
Mediator of RNA polymerase II transcription subunit 15

1

1

High-throughput

0.536

High

518898

PKP4
Plakophilin-4

1

2

High-throughput

0.536

High

518899

PKP2
Plakophilin-2

1

3

High-throughput

0.536

High

518900

SEM3C
Semaphorin-3C

1

1

High-throughput

0.536

High

518903

EMIL2
EMILIN-2

1

7

High-throughput

0.536

High

518908

CRLD1
Cysteine-rich secretory protein LCCL domain-containing 1

1

1

High-throughput

0.536

High

518916

EMIL3
EMILIN-3

1

10

High-throughput

0.536

High

518920

F120A
Constitutive coactivator of PPAR-gamma-like protein 1

1

1

High-throughput

0.536

High

518923

EXTL2
Exostosin-like 2

1

2

High-throughput

0.536

High

518927

EGFL7
Epidermal growth factor-like protein 7

1

15

High-throughput

0.536

High

518928

ATS1
A disintegrin and metalloproteinase with thrombospondin motifs 1

1

4

High-throughput

0.536

High

518930

METRN
Meteorin

1

1

High-throughput

0.536

High

518931

TNIK
TRAF2 and NCK-interacting protein kinase

1

2

High-throughput

0.536

High

518932

PCOC2
Procollagen C-endopeptidase enhancer 2

1

8

High-throughput

0.536

High

67606

RHG32
Rho GTPase-activating protein 32

1

0

High-throughput

0.513

High

331954

KAT7
Histone acetyltransferase KAT7

1

0

High-throughput

0.513

High

339314

MET18
Histidine protein methyltransferase 1 homolog

1

0

High-throughput

0.513

High

441406

CHLE
Cholinesterase

1

0

High-throughput

0.513

High

466994

DAF
Complement decay-accelerating factor

1

0

High-throughput

0.513

High

471575

CO4A2

1

0

High-throughput

0.513

High

477325

NMB
Neuromedin-B [Cleaved into: Neuromedin-B-32; Neuromedin-B]

1

0

High-throughput

0.513

High

518808

AMD
Peptidyl-glycine alpha-amidating monooxygenase

1

0

High-throughput

0.513

High

518811

RBMS1
RNA-binding motif, single-stranded-interacting protein 1

1

0

High-throughput

0.513

High

518824

EPHB4
Ephrin type-B receptor 4

1

0

High-throughput

0.513

High

518825

PLTP
Phospholipid transfer protein

1

0

High-throughput

0.513

High

518830

RL23
Large ribosomal subunit protein uL14

1

0

High-throughput

0.513

High

518835

LOXL1
Lysyl oxidase homolog 1

1

0

High-throughput

0.513

High

518837

MGT5A
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A

1

0

High-throughput

0.513

High

518839

PTPRS
Receptor-type tyrosine-protein phosphatase S

1

0

High-throughput

0.513

High

518840

DAG1
Dystroglycan 1

1

0

High-throughput

0.513

High

518843

LTBP1
Latent-transforming growth factor beta-binding protein 1

1

0

High-throughput

0.513

High

518849

CGT
2-hydroxyacylsphingosine 1-beta-galactosyltransferase

1

0

High-throughput

0.513

High

518854

ANGE2
Protein angel homolog 2

1

0

High-throughput

0.513

High

518858

ABH15
Protein ABHD15

1

0

High-throughput

0.513

High

518862

MON1B
Vacuolar fusion protein MON1 homolog B

1

0

High-throughput

0.513

High

518864

FJX1
Four-jointed box protein 1

1

0

High-throughput

0.513

High

518867

DYR2
Dihydrofolate reductase 2, mitochondrial

1

0

High-throughput

0.513

High

518876

PCYXL
Prenylcysteine oxidase 1-like

1

0

High-throughput

0.513

High

518878

DIK2A
Divergent protein kinase domain 2A

1

0

High-throughput

0.513

High

518885

PXDN
Peroxidasin homolog

1

0

High-throughput

0.513

High

518894

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

High-throughput

0.513

High

518897

STRBP
Spermatid perinuclear RNA-binding protein

1

0

High-throughput

0.513

High

518901

PXL2A
Peroxiredoxin-like 2A

1

0

High-throughput

0.513

High

518902

CHID1
Chitinase domain-containing protein 1

1

0

High-throughput

0.513

High

518906

CCDC8
Coiled-coil domain-containing protein 8

1

0

High-throughput

0.513

High

518907

XYLT2
Xylosyltransferase 2

1

0

High-throughput

0.513

High

518910

FKRP
Ribitol 5-phosphate transferase FKRP

1

0

High-throughput

0.513

High

518913

VEZA
Vezatin

1

0

High-throughput

0.513

High

518917

DDX28
Probable ATP-dependent RNA helicase DDX28

1

0

High-throughput

0.513

High

518929

CEIP2
Cell surface hyaluronidase CEMIP2

1

0

High-throughput

0.513

High

518933

PPT2
Lysosomal thioesterase PPT2

1

0

High-throughput

0.513

High

518935

HPSE
Heparanase

1

0

High-throughput

0.513

High

518937

NDK7
Nucleoside diphosphate kinase homolog 7

1

0

High-throughput

0.513

High

182900

NKRF
NF-kappa-B-repressing factor

1

1

High-throughput

0.489

High

212051

B4GT5
Beta-1,4-galactosyltransferase 5

1

5

High-throughput

0.489

High

284920

TAF5L
TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L

1

2

High-throughput

0.489

High

338225

G6PE
GDH/6PGL endoplasmic bifunctional protein [Includes: Hexose-6-phosphate dehydrogenase

1

1

High-throughput

0.489

High

518842

PDIA5
Protein disulfide-isomerase A5

1

3

High-throughput

0.489

High

518848

EXT1
Exostosin-1

1

2

High-throughput

0.489

High

518851

EOGT
EGF domain-specific O-linked N-acetylglucosamine transferase

1

1

High-throughput

0.489

High

518855

CAHD1
VWFA and cache domain-containing protein 1

1

1

High-throughput

0.489

High

518857

GLT18
Polypeptide N-acetylgalactosaminyltransferase 18

1

4

High-throughput

0.489

High

518859

B3GLT
Beta-1,3-glucosyltransferase

1

6

High-throughput

0.489

High

518860

CHSS3
Chondroitin sulfate synthase 3

1

7

High-throughput

0.489

High

518863

GALT7
N-acetylgalactosaminyltransferase 7

1

4

High-throughput

0.489

High

518865

AMZ2
Archaemetzincin-2

1

4

High-throughput

0.489

High

518873

LARG2
Xylosyl- and glucuronyltransferase LARGE2

1

1

High-throughput

0.489

High

518874

GLT16
Polypeptide N-acetylgalactosaminyltransferase 16

1

4

High-throughput

0.489

High

518877

GALT6
Polypeptide N-acetylgalactosaminyltransferase 6

1

4

High-throughput

0.489

High

518893

C2AIL
CDKN2AIP N-terminal-like protein

1

1

High-throughput

0.489

High

518914

C1GLT
Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1

1

6

High-throughput

0.489

High

518918

F120C
Constitutive coactivator of PPAR-gamma-like protein 2

1

1

High-throughput

0.489

High

518919

CARF
CDKN2A-interacting protein

1

2

High-throughput

0.489

High

518921

CHPF2
Chondroitin sulfate glucuronyltransferase

1

7

High-throughput

0.489

High

518924

B4GT7
Beta-1,4-galactosyltransferase 7

1

5

High-throughput

0.489

High

518925

B4GT6
Beta-1,4-galactosyltransferase 6

1

5

High-throughput

0.489

High

518936

HS3S2
Heparan sulfate glucosamine 3-O-sulfotransferase 2

1

2

High-throughput

0.489

High

518938

HS3SB
Heparan sulfate glucosamine 3-O-sulfotransferase 3B1

1

2

High-throughput

0.489

High

518804

CREB1
Cyclic AMP-responsive element-binding protein 1

1

2

Small-scale

0.479

High

518805

CEBPB
CCAAT/enhancer-binding protein beta

1

5

Small-scale

0.479

High

518817

SYUA
Alpha-synuclein

1

0

High-throughput

0.460

High

518829

RS4X
Small ribosomal subunit protein eS4, X isoform

1

0

High-throughput

0.458

High

456179

CATD
Cathepsin D

1

3

Small-scale

0.445

High

63742

KRBA1
Protein KRBA1

1

0

High-throughput

0.279

Low

239480

H6ST1
Heparan-sulfate 6-O-sulfotransferase 1

1

0

High-throughput

0.279

Low

283590

SUPT3
Transcription initiation protein SPT3 homolog

1

0

High-throughput

0.279

Low

322128

GLCE
D-glucuronyl C5-epimerase

1

0

High-throughput

0.279

Low

326233

PRS23
Serine protease 23

1

0

High-throughput

0.279

Low

518807

XRCC1
DNA repair protein XRCC1

1

0

High-throughput

0.279

Low

518810

MGAT1
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

1

0

High-throughput

0.279

Low

518832

CCZ1B
Vacuolar fusion protein CCZ1 homolog B

1

0

High-throughput

0.279

Low

518834

FOXM1
Forkhead box protein M1

1

0

High-throughput

0.279

Low

518846

NPTX1
Neuronal pentraxin-1

1

0

High-throughput

0.279

Low

518853

MANEL
Glycoprotein endo-alpha-1,2-mannosidase-like protein

1

0

High-throughput

0.279

Low

518869

P3H3
Prolyl 3-hydroxylase 3

1

0

High-throughput

0.279

Low

518872

K319L
Dyslexia-associated protein KIAA0319-like protein

1

0

High-throughput

0.279

Low

518875

PGLT1
Protein O-glucosyltransferase 1

1

0

High-throughput

0.279

Low

518882

PXYP1
2-phosphoxylose phosphatase 1

1

0

High-throughput

0.279

Low

518883

PHF3
PHD finger protein 3

1

0

High-throughput

0.279

Low

518887

RUSD4
Pseudouridylate synthase RPUSD4, mitochondrial

1

0

High-throughput

0.279

Low

518888

RMC1
Regulator of MON1-CCZ1 complex

1

0

High-throughput

0.279

Low

518891

MED8
Mediator of RNA polymerase II transcription subunit 8

1

0

High-throughput

0.279

Low

518892

P121A
Nuclear envelope pore membrane protein POM 121

1

0

High-throughput

0.279

Low

518904

FUT8
Alpha-(1,6)-fucosyltransferase

1

0

High-throughput

0.279

Low

518905

XRN2
5'-3' exoribonuclease 2

1

0

High-throughput

0.279

Low

518909

OFUT1
GDP-fucose protein O-fucosyltransferase 1

1

0

High-throughput

0.279

Low

518911

PATZ1
POZ-, AT hook-, and zinc finger-containing protein 1

1

0

High-throughput

0.279

Low

518912

DEFM
Peptide deformylase, mitochondrial

1

0

High-throughput

0.279

Low

518915

CHST7
Carbohydrate sulfotransferase 7

1

0

High-throughput

0.279

Low

518922

TXD16
Thioredoxin domain-containing protein 16

1

0

High-throughput

0.279

Low

518833

RUNX1
Runt-related transcription factor 1

1

0

Small-scale

0.269

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025