Interactor 1: FCG2A (P12318)
Low affinity immunoglobulin gamma Fc region receptor II-a (IgG Fc receptor II-a) (CDw32) (Fc-gamma RII-a) (Fc-gamma-RIIa) (FcRII-a) (CD antigen CD32)
Gene: FCGR2A

Interactor 2: FCG2C (P31995)
Low affinity immunoglobulin gamma Fc region receptor II-c (IgG Fc receptor II-c) (CDw32) (Fc-gamma RII-c) (Fc-gamma-RIIc) (FcRII-c) (CD antigen CD32)
Gene: FCGR2C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.861

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ig_2~Ig_2
Common GO terms GO:0001788 - antibody-dependent cellular cytotoxicity
GO:0007166 - cell surface receptor signaling pathway
GO:0009897 - external side of plasma membrane
GO:0019770 - IgG receptor activity
GO:0019864 - IgG binding
and 2 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 317
Hs

1 323
+ Hs
+ Dm
+ Ce
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+ Hs
+ Mm
+ Dm
+ Dm
+ Dm
+ Hs
+ Hs
+ Rn
+ Hs
+ Hs
+ Hs
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+ Hs

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Last updated: 15 Jul 2024