HitPredict

Interactor 1: KAPC1 (P12370)
cAMP-dependent protein kinase catalytic subunit 1 (PKA C) (EC 2.7.11.11) (Protein kinase DC0)
Gene: Pka-C1

Interactor 2: CNN (P54623)
Centrosomin (Protein arrow)
Gene: CNN

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.50	0.464

Property	Details
Experiments	14605208
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 353 Dm			1 1320
+	Hs
		610736 KAPCB_HUMAN (1-353): 5.59e-158: 448: 82.15		MYOME_HUMAN (43-690): 1.97e-109: 384: 20.51
+	Hs
		568700 KAPCA_HUMAN (1-353): 7.35e-158: 447: 82.44		MYOME_HUMAN (43-690): 1.97e-109: 384: 20.51
+	Hs
		609676 KAPCG_HUMAN (1-353): 1.47e-156: 444: 74.50		MYOME_HUMAN (43-690): 1.97e-109: 384: 20.51
+	Mm
		933112 KAPCB_MOUSE (1-353): 8.1e-156: 442: 81.59		MYOME_MOUSE (43-1039): 9.45e-89: 320: 16.93
+	Hs
		610771 KAPCB_HUMAN (1-353): 5.59e-158: 448: 82.15		CK5P2_HUMAN (36-600): 3.48e-57: 220: 17.55
+	Hs
		568772 KAPCA_HUMAN (1-353): 7.35e-158: 447: 82.44		CK5P2_HUMAN (36-600): 3.48e-57: 220: 17.55
+	Hs
		610802 KAPCB_HUMAN (1-353): 5.59e-158: 448: 82.15		MYH4_HUMAN (615-1320): 7.34e-26: 118: 12.27
+	Hs
		528359 KAPCB_HUMAN (1-353): 5.59e-158: 448: 82.15		MYH6_HUMAN (676-1314): 3.88e-22: 106: 10.59
+	Hs
		610795 KAPCB_HUMAN (1-353): 5.59e-158: 448: 82.15		MYH2_HUMAN (812-1318): 8.45e-20: 98.5: 11.57
+	Hs
		522538 KAPCB_HUMAN (1-353): 5.59e-158: 448: 82.15		MYH1_HUMAN (812-1318): 1.17e-18: 95: 11.77
+	Hs
		568689 KAPCA_HUMAN (1-353): 7.35e-158: 447: 82.44		GRDN_HUMAN (657-1298): 1.86e-16: 87.8: 14.29
+	Hs
		568568 KAPCA_HUMAN (1-353): 7.35e-158: 447: 82.44		MYH10_HUMAN (1-462): 1.31e-13: 78.5: 10.82
+	Hs
		681881 AKT1_HUMAN (20-349): 3.04e-147: 425: 38.81		GRDN_HUMAN (657-1298): 1.86e-16: 87.8: 14.29
+	Hs
		568567 KAPCA_HUMAN (1-353): 7.35e-158: 447: 82.44		MYH9_HUMAN (1010-1320): 8.14e-10: 65.7: 11.58
+	Hs
		623875 KPCL_HUMAN (2-353): 7.93e-146: 429: 36.54		PLEC_HUMAN (35-1148): 7.16e-13: 76.1: 14.62
+	Mm
		1130947 AKT2_MOUSE (2-349): 5.22e-149: 430: 36.08		GRDN_MOUSE (681-1299): 1.42e-12: 74.7: 10.65
+	Mm
		682109 AKT1_MOUSE (20-349): 7.62e-148: 427: 39.10		GRDN_MOUSE (681-1299): 1.42e-12: 74.7: 10.65
+	Hs
		551616 AKT1_HUMAN (20-349): 3.04e-147: 425: 38.81		DESP_HUMAN (43-693): 3.53e-12: 73.8: 16.04
+	Hs
		681696 AKT1_HUMAN (20-349): 3.04e-147: 425: 38.81		MYH9_HUMAN (1010-1320): 8.14e-10: 65.7: 11.58
+	Hs
		116964 SGK1_HUMAN (41-336): 5.46e-83: 260: 42.19		MYH1_HUMAN (812-1318): 1.17e-18: 95: 11.77