Protein: MYB
Transcriptional activator Myb (Proto-oncogene c-Myb)

Gene: MYB
Organism: Homo sapiens
Interactions: 146
UniProt ID: P10242

Gene Ontology (top 5):
GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000278 - mitotic cell cycle
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

519407

CBP
CREB-binding protein

7

9

Small-scale

0.971

High

519369

EP300
Histone acetyltransferase p300

6

13

Small-scale

0.937

High

278213

NCOR1
Nuclear receptor corepressor 1

2

7

Small-scale

0.806

High

519430

NLK
Serine/threonine-protein kinase NLK

2

20

Small-scale

0.657

High

519350

SMCA2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2

1

20

Small-scale

0.647

High

519408

KAT2A
Histone acetyltransferase KAT2A

1

8

Small-scale

0.647

High

519363

UBC9
SUMO-conjugating enzyme UBC9

3

5

Small-scale

0.647

High

519421

HIPK2
Homeodomain-interacting protein kinase 2

2

20

Small-scale

0.636

High

519410

FBXW7
F-box/WD repeat-containing protein 7

2

4

Small-scale

0.624

High

519320

MYB
Transcriptional activator Myb

1

15

Small-scale

0.618

High

519420

PAIP1
Polyadenylate-binding protein-interacting protein 1

2

1

High-throughput

0.606

High

297417

PIAS1
E3 SUMO-protein ligase PIAS1

2

2

Small-scale

0.605

High

519443

TRAF6
TNF receptor-associated factor 6

2

3

Small-scale

0.601

High

175828

SET1A
Histone-lysine N-methyltransferase SETD1A

2

7

High-throughput

0.584

High

519388

LIN9
Protein lin-9 homolog

2

3

Small-scale

0.584

High

519337

PML
Protein PML

1

6

Small-scale

0.561

High

519343

RL4
Large ribosomal subunit protein uL4

1

1

Small-scale

0.561

High

519371

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

10

Small-scale

0.561

High

519373

TIF1B
Transcription intermediary factor 1-beta

1

6

Small-scale

0.561

High

519417

SIN3A
Paired amphipathic helix protein Sin3a

1

5

Small-scale

0.561

High

519424

RENT2
Regulator of nonsense transcripts 2

1

1

High-throughput

0.561

High

519333

SP100
Nuclear autoantigen Sp-100

1

4

High-throughput

0.541

High

519338

CCND3
G1/S-specific cyclin-D3

1

5

High-throughput

0.541

High

519383

HLF
Hepatic leukemia factor

1

7

High-throughput

0.541

High

519323

SKI
Ski oncogene

1

0

Small-scale

0.537

High

519365

CLH1
Clathrin heavy chain 1

1

2

Small-scale

0.536

High

177105

ERC2
ERC protein 2

1

4

High-throughput

0.528

High

519358

SUMO2
Small ubiquitin-related modifier 2

1

2

Small-scale

0.527

High

519362

SUMO1
Small ubiquitin-related modifier 1

1

2

Small-scale

0.527

High

282154

MAF
Transcription factor Maf

1

1

Small-scale

0.527

High

519378

ZMY11
Zinc finger MYND domain-containing protein 11

1

7

Small-scale

0.527

High

519393

SND1
Staphylococcal nuclease domain-containing protein 1

1

1

Small-scale

0.527

High

519425

MYOZ2
Myozenin-2

1

0

High-throughput

0.518

High

519379

CEBPE
CCAAT/enhancer-binding protein epsilon

1

8

Small-scale

0.501

High

519385

H31T
Histone H3.1t

1

4

Small-scale

0.501

High

519402

PPM1K
Protein phosphatase Mn(2+)-dependent 1K

1

2

High-throughput

0.494

High

519361

RBX1
E3 ubiquitin-protein ligase RBX1

1

0

Small-scale

0.480

High

122700

KIF2A
Kinesin-like protein KIF2A

1

5

High-throughput

0.479

High

161398

KMT2D
Histone-lysine N-methyltransferase 2D

1

10

High-throughput

0.479

High

177429

ZN536
Zinc finger protein 536

1

1

High-throughput

0.479

High

244635

ZC3H1
Zinc finger C3H1 domain-containing protein

1

1

High-throughput

0.479

High

245579

ZEB2
Zinc finger E-box-binding homeobox 2

1

2

High-throughput

0.479

High

282661

E2F6
Transcription factor E2F6

1

6

High-throughput

0.479

High

344855

WIZ
Protein Wiz

1

1

High-throughput

0.479

High

486881

PARP1
Poly [ADP-ribose] polymerase 1

1

5

Small-scale

0.479

High

519321

IRF1
Interferon regulatory factor 1

1

2

Small-scale

0.479

High

519322

HSP7C
Heat shock cognate 71 kDa protein

1

4

Small-scale

0.479

High

519324

NR2C1
Nuclear receptor subfamily 2 group C member 1

1

5

High-throughput

0.479

High

519325

IRF2
Interferon regulatory factor 2

1

2

Small-scale

0.479

High

519326

ZEP1
Zinc finger protein 40

1

1

High-throughput

0.479

High

519327

TAL1
T-cell acute lymphocytic leukemia protein 1

1

1

Small-scale

0.479

High

519329

EGR1
Early growth response protein 1

1

2

Small-scale

0.479

High

519330

NUCL
Nucleolin

1

2

Small-scale

0.479

High

519334

GATA3
Trans-acting T-cell-specific transcription factor GATA-3

1

2

Small-scale

0.479

High

519336

TYY1
Transcriptional repressor protein YY1

1

1

High-throughput

0.479

High

519342

BMI1
Polycomb complex protein BMI-1

1

4

Small-scale

0.479

High

519344

ZEB1
Zinc finger E-box-binding homeobox 1

1

2

High-throughput

0.479

High

519345

CUX1
Homeobox protein cut-like 1

1

5

High-throughput

0.479

High

519346

STA5A
Signal transducer and activator of transcription 5A

1

1

Small-scale

0.479

High

519348

CTCF
Transcriptional repressor CTCF

1

1

High-throughput

0.479

High

519349

CEBPA
CCAAT/enhancer-binding protein alpha

1

6

High-throughput

0.479

High

519352

BLM
RecQ-like DNA helicase BLM

1

6

High-throughput

0.479

High

519359

WDR5
WD repeat-containing protein 5

1

8

Small-scale

0.479

High

519367

PAX5
Paired box protein Pax-5

1

2

Small-scale

0.479

High

519368

KMT2A
Histone-lysine N-methyltransferase 2A

1

8

Small-scale

0.479

High

519370

NFIA
Nuclear factor 1 A-type

1

7

High-throughput

0.479

High

519372

RLF
Zinc finger protein Rlf

1

1

High-throughput

0.479

High

519375

CUL4A
Cullin-4A

1

3

Small-scale

0.479

High

519377

RBBP5
Retinoblastoma-binding protein 5

1

8

Small-scale

0.479

High

519381

EZH2
Histone-lysine N-methyltransferase EZH2

1

9

Small-scale

0.479

High

519382

DDB1
DNA damage-binding protein 1

1

3

Small-scale

0.479

High

519391

NIPBL
Nipped-B-like protein

1

5

High-throughput

0.479

High

519392

PAXI1
PAX-interacting protein 1

1

5

High-throughput

0.479

High

519394

KANL1
KAT8 regulatory NSL complex subunit 1

1

1

High-throughput

0.479

High

519395

POGZ
Pogo transposable element with ZNF domain

1

1

High-throughput

0.479

High

519396

EMSY
BRCA2-interacting transcriptional repressor EMSY

1

5

High-throughput

0.479

High

519398

ARI3B
AT-rich interactive domain-containing protein 3B

1

3

High-throughput

0.479

High

519399

MGAP
MAX gene-associated protein

1

2

High-throughput

0.479

High

519400

PHF6
PHD finger protein 6

1

4

High-throughput

0.479

High

519401

KMT2E
Inactive histone-lysine N-methyltransferase 2E

1

5

High-throughput

0.479

High

519404

KDM2B
Lysine-specific demethylase 2B

1

3

High-throughput

0.479

High

519405

GATD1
GATA zinc finger domain-containing protein 1

1

1

High-throughput

0.479

High

519406

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

2

High-throughput

0.479

High

519409

KAT5
Histone acetyltransferase KAT5

1

2

Small-scale

0.479

High

519413

ZBTB9
Zinc finger and BTB domain-containing protein 9

1

7

High-throughput

0.479

High

519414

ZBT10
Zinc finger and BTB domain-containing protein 10

1

3

High-throughput

0.479

High

519415

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

5

High-throughput

0.479

High

519416

CIC
Protein capicua homolog

1

5

High-throughput

0.479

High

519418

ARI3A
AT-rich interactive domain-containing protein 3A

1

3

High-throughput

0.479

High

519419

PCGF6
Polycomb group RING finger protein 6

1

4

High-throughput

0.479

High

519422

ZN644
Zinc finger protein 644

1

1

High-throughput

0.479

High

519423

EHMT1
Histone-lysine N-methyltransferase EHMT1

1

4

High-throughput

0.479

High

519427

CXXC1
CXXC-type zinc finger protein 1

1

7

High-throughput

0.479

High

519428

CHD7
Chromodomain-helicase-DNA-binding protein 7

1

11

High-throughput

0.479

High

519431

ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2

1

5

Small-scale

0.479

High

519432

TRPS1
Zinc finger transcription factor Trps1

1

4

High-throughput

0.479

High

519434

LEF1
Lymphoid enhancer-binding factor 1

1

5

Small-scale

0.479

High

519436

KMT2B
Histone-lysine N-methyltransferase 2B

1

8

High-throughput

0.479

High

519437

PHF8
Histone lysine demethylase PHF8

1

5

High-throughput

0.479

High

519439

SMC3
Structural maintenance of chromosomes protein 3

1

5

High-throughput

0.479

High

519440

ZN148
Zinc finger protein 148

1

1

High-throughput

0.479

High

519441

ZN281
Zinc finger protein 281

1

1

High-throughput

0.479

High

96609

E9PAV9
G patch domain-containing protein 4

1

0

High-throughput

0.458

High

128735

MEN1
Menin

1

0

Small-scale

0.458

High

238362

RAD21
Double-strand-break repair protein rad21 homolog

1

0

High-throughput

0.458

High

424310

IL4
Interleukin-4

1

0

Small-scale

0.458

High

519331

PTMS
Parathymosin

1

0

High-throughput

0.458

High

519341

IL13
Interleukin-13

1

0

Small-scale

0.458

High

519347

RL34
Large ribosomal subunit protein eL34

1

0

High-throughput

0.458

High

519351

ZN131
Zinc finger protein 131

1

0

High-throughput

0.458

High

519353

ATX1
Ataxin-1

1

0

High-throughput

0.458

High

519354

AF17
Protein AF-17

1

0

High-throughput

0.458

High

519355

NLRP6
NACHT, LRR and PYD domains-containing protein 6

1

0

High-throughput

0.458

High

519356

RL37A
Large ribosomal subunit protein eL43

1

0

High-throughput

0.458

High

519366

BEX3
Protein BEX3

1

0

High-throughput

0.458

High

519374

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

0

Small-scale

0.458

High

519384

TAF9
Transcription initiation factor TFIID subunit 9

1

0

High-throughput

0.458

High

519386

BEND3
BEN domain-containing protein 3

1

0

High-throughput

0.458

High

519397

KAISO
Transcriptional regulator Kaiso

1

0

High-throughput

0.458

High

519403

ZN709
Zinc finger protein 709

1

0

High-throughput

0.458

High

519411

LMBL2
Lethal(3)malignant brain tumor-like protein 2

1

0

High-throughput

0.458

High

519412

FBXW5
F-box/WD repeat-containing protein 5

1

0

Small-scale

0.458

High

519429

KANL3
KAT8 regulatory NSL complex subunit 3

1

0

High-throughput

0.458

High

519433

DACH1
Dachshund homolog 1

1

0

High-throughput

0.458

High

519435

FBXL5
F-box/LRR-repeat protein 5

1

0

High-throughput

0.458

High

519438

SATB2
DNA-binding protein SATB2

1

0

High-throughput

0.458

High

519442

NOP16
Nucleolar protein 16

1

0

High-throughput

0.458

High

482996

CLCA
Clathrin light chain A

1

1

Small-scale

0.445

High

519328

CEBPB
CCAAT/enhancer-binding protein beta

1

7

Small-scale

0.445

High

519332

FLNA
Filamin-A

1

3

Small-scale

0.445

High

519376

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

9

Small-scale

0.445

High

519380

MK11
Mitogen-activated protein kinase 11

1

20

Small-scale

0.445

High

189052

NCAM2
Neural cell adhesion molecule 2

1

1

High-throughput

0.437

High

519387

NBPFE
NBPF family member NBPF14

1

2

High-throughput

0.437

High

519389

ZMYM4
Zinc finger MYM-type protein 4

1

1

High-throughput

0.437

High

418801

H2A1B
Histone H2A type 1-B/E

1

1

Small-scale

0.408

High

519339

H2B1B
Histone H2B type 1-B

1

2

Small-scale

0.408

High

519360

H4
Histone H4

1

2

Small-scale

0.408

High

519364

H31
Histone H3.1

1

4

Small-scale

0.408

High

519357

LYSC
Lysozyme C

1

0

Small-scale

0.269

Low

167729

PCD17
Protocadherin-17

1

0

High-throughput

0.249

Low

519335

COX7B
Cytochrome c oxidase subunit 7B, mitochondrial

1

0

High-throughput

0.249

Low

519340

SDC2
Syndecan-2

1

0

High-throughput

0.249

Low

519390

DCA15
DDB1- and CUL4-associated factor 15

1

0

High-throughput

0.249

Low

519426

ADA22
Disintegrin and metalloproteinase domain-containing protein 22

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025