Interactor 1: ACHB4 (P12392)
Neuronal acetylcholine receptor subunit beta-4 (Neuronal acetylcholine receptor non-alpha-2 chain) (N-alpha 2)
Gene: Chrnb4

Interactor 2: ACHA5 (P20420)
Neuronal acetylcholine receptor subunit alpha-5
Gene: Chrna5

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 20566638
Identification Methods anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Neur_chan_LBD~Neur_chan_LBD, Neur_chan_LBD~Neur_chan_memb, Neur_chan_memb~Neur_chan_memb
Common GO terms GO:0005886 - plasma membrane
GO:0005892 - acetylcholine-gated channel complex
GO:0015464 - acetylcholine receptor activity
GO:0022848 - acetylcholine-gated monoatomic cation-selective channel activity
GO:0035094 - response to nicotine
and 8 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 495
Rn

1 452
+ Rn
+ Hs
+ Hs
+ Gg
+ Rn
+ Hs
+ Gg
+ Gg
+ Hs
+ Gg
+ Rn
+ Gg
+ Rn
+ Rn
+ Hs
+ Rn
+ Gg

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024