HitPredict

Interactor 1: ANXA3 (P12429)
Annexin A3 (35-alpha calcimedin) (Annexin III) (Annexin-3) (Inositol 1,2-cyclic phosphate 2-phosphohydrolase) (Lipocortin III) (Placental anticoagulant protein III) (PAP-III)
Gene: ANXA3

Interactor 2: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	26618866, 29924966
Identification Methods	affinity chromatography technology, pull down, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 323 Hs			1 1480
+	Hs
		444819 ANXA5_HUMAN (4-323): 7.02e-163: 458: 49.38		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529242 AXA81_HUMAN (3-322): 9.39e-162: 455: 49.07		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		427420 ANXA2_HUMAN (9-323): 1.28e-156: 443: 48.42		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		376145 ANXA1_HUMAN (7-322): 1.33e-155: 440: 49.68		CFTR_HUMAN (1-1480): 0: 1031: 100.00