HitPredict

Interactor 1: BMP4 (P12644)
Bone morphogenetic protein 4 (BMP-4) (Bone morphogenetic protein 2B) (BMP-2B)
Gene: BMP4

Interactor 2: BMR1A (P36894)
Bone morphogenetic protein receptor type-1A (BMP type-1A receptor) (BMPR-1A) (EC 2.7.11.30) (Activin receptor-like kinase 3) (ALK-3) (Serine/threonine-protein kinase receptor R5) (SKR5) (CD antigen CD292)
Gene: BMPR1A

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.915

The method score is based on:

Property Details
Experiments 28126904, 27684187, 8006002, 20860622, 21054789
Identification Methods pull down, affinity chromatography technology, surface plasmon resonance
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Activin_recp~TGF_beta
Common GO terms GO:0001649 - osteoblast differentiation
GO:0002062 - chondrocyte differentiation
GO:0003148 - outflow tract septum morphogenesis
GO:0010628 - positive regulation of gene expression
GO:0010629 - negative regulation of gene expression
and 11 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 408
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024