Protein: ERR2
Steroid hormone receptor ERR2 (Estrogen receptor-like 2) (Estrogen-related receptor beta) (ERR-beta) (Nuclear receptor subfamily 3 group B member 2)

Gene: ERR2, Esrrb
Organism: Mus musculus
Interactions: 179
UniProt ID: Q61539

Gene Ontology (top 5):
GO:0000793 - condensed chromosome
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0000987 - cis-regulatory region sequence-specific DNA binding
GO:0000993 - RNA polymerase II complex binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1222236

NR0B1
Nuclear receptor subfamily 0 group B member 1

3

20

Small-scale

0.855

High

147638

ERR1
Steroid hormone receptor ERR1

2

19

High-throughput

0.789

High

629293

PO5F1
POU domain, class 5, transcription factor 1

3

20

Small-scale

0.656

High

1222851

NANOG
Homeobox protein NANOG

3

16

Small-scale

0.656

High

1190624

TF2L1
Transcription factor CP2-like protein 1

2

11

High-throughput

0.621

High

1222868

EP400
E1A-binding protein p400

2

20

High-throughput

0.621

High

1222836

FKB15
FK506-binding protein 15

1

20

High-throughput

0.618

High

63103

A5D6Q2
Nuclear receptor coactivator 3

1

20

High-throughput

0.618

High

947435

LMBL2
Lethal(3)malignant brain tumor-like protein 2

2

6

Small-scale

0.611

High

1204119

EHMT1
Histone-lysine N-methyltransferase EHMT1

2

20

High-throughput

0.611

High

1222457

HCFC1
Host cell factor 1

2

8

High-throughput

0.611

High

1222853

UBIP1
Upstream-binding protein 1

2

11

High-throughput

0.611

High

1222867

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

2

20

High-throughput

0.611

High

1222884

ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2

2

20

High-throughput

0.611

High

1222914

TFCP2
Alpha-globin transcription factor CP2

2

11

High-throughput

0.611

High

1222915

DMAP1
DNA methyltransferase 1-associated protein 1

2

3

High-throughput

0.611

High

1222922

MBD3
Methyl-CpG-binding domain protein 3

2

6

High-throughput

0.611

High

872997

SOX2
Transcription factor SOX-2

2

20

Small-scale

0.595

High

1222882

P66B
Transcriptional repressor p66-beta

2

6

High-throughput

0.584

High

1053213

Q05BA5
Nuclear receptor coactivator

1

20

High-throughput

0.575

High

1222918

MTA2
Metastasis-associated protein MTA2

1

20

High-throughput

0.565

High

476225

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

5

High-throughput

0.554

High

1222860

SALL4
Sal-like protein 4

1

17

High-throughput

0.554

High

1222890

MED1
Mediator of RNA polymerase II transcription subunit 1

1

20

High-throughput

0.554

High

59238

MED14
Mediator of RNA polymerase II transcription subunit 14

1

20

High-throughput

0.536

High

59312

MED12
Mediator of RNA polymerase II transcription subunit 12

1

20

High-throughput

0.536

High

60012

ARI1A
AT-rich interactive domain-containing protein 1A

1

20

High-throughput

0.536

High

98338

E9QLK7
Transformation/transcription domain-associated protein

1

14

High-throughput

0.536

High

148699

HDAC1
Histone deacetylase 1

1

20

High-throughput

0.536

High

312023

WIZ
Protein Wiz

1

20

High-throughput

0.536

High

706374

TBP
TATA-box-binding protein

1

6

High-throughput

0.536

High

965390

WDR5
WD repeat-containing protein 5

1

17

High-throughput

0.536

High

1000012

HDAC2
Histone deacetylase 2

1

20

High-throughput

0.536

High

1021780

SMRC1
SWI/SNF complex subunit SMARCC1

1

20

High-throughput

0.536

High

1189437

SMCA4
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

1

20

High-throughput

0.536

High

1211122

MED13
Mediator of RNA polymerase II transcription subunit 13

1

5

High-throughput

0.536

High

1222061

RBBP4
Histone-binding protein RBBP4

1

20

High-throughput

0.536

High

1222317

REQU
Zinc finger protein ubi-d4

1

20

High-throughput

0.536

High

1222768

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

1

20

High-throughput

0.536

High

1222824

TAF6
Transcription initiation factor TFIID subunit 6

1

4

High-throughput

0.536

High

1222826

JHD2C
Probable JmjC domain-containing histone demethylation protein 2C

1

7

High-throughput

0.536

High

1222840

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

20

High-throughput

0.536

High

1222844

RIF1
Telomere-associated protein RIF1

1

20

High-throughput

0.536

High

1222850

MED23
Mediator of RNA polymerase II transcription subunit 23

1

3

High-throughput

0.536

High

1222859

RBBP5
Retinoblastoma-binding protein 5

1

14

High-throughput

0.536

High

1222862

MED19
Mediator of RNA polymerase II transcription subunit 19

1

1

High-throughput

0.536

High

1222863

NRIP1
Nuclear receptor-interacting protein 1

1

16

High-throughput

0.536

High

1222864

ZBTB9
Zinc finger and BTB domain-containing protein 9

1

20

High-throughput

0.536

High

1222866

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

4

High-throughput

0.536

High

1222870

TAF10
Transcription initiation factor TFIID subunit 10

1

1

High-throughput

0.536

High

1222873

MTA1
Metastasis-associated protein MTA1

1

19

High-throughput

0.536

High

1222875

BRD8
Bromodomain-containing protein 8

1

20

High-throughput

0.536

High

1222876

CDK8
Cyclin-dependent kinase 8

1

13

High-throughput

0.536

High

1222877

MED25
Mediator of RNA polymerase II transcription subunit 25

1

8

High-throughput

0.536

High

1222878

MED17
Mediator of RNA polymerase II transcription subunit 17

1

4

High-throughput

0.536

High

1222881

ING3
Inhibitor of growth protein 3

1

7

High-throughput

0.536

High

1222883

TAF9
Transcription initiation factor TFIID subunit 9

1

5

High-throughput

0.536

High

1222885

SMCA5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

1

20

High-throughput

0.536

High

1222886

MED6
Mediator of RNA polymerase II transcription subunit 6

1

3

High-throughput

0.536

High

1222889

MTA3
Metastasis-associated protein MTA3

1

20

High-throughput

0.536

High

1222893

MED24
Mediator of RNA polymerase II transcription subunit 24

1

4

High-throughput

0.536

High

1222896

MED4
Mediator of RNA polymerase II transcription subunit 4

1

4

High-throughput

0.536

High

1222897

MED30
Mediator of RNA polymerase II transcription subunit 30

1

1

High-throughput

0.536

High

1222899

YETS4
YEATS domain-containing protein 4

1

7

High-throughput

0.536

High

1222900

MED18
Mediator of RNA polymerase II transcription subunit 18

1

1

High-throughput

0.536

High

1222901

MED7
Mediator of RNA polymerase II transcription subunit 7

1

3

High-throughput

0.536

High

1222903

KAT8
Histone acetyltransferase KAT8

1

9

High-throughput

0.536

High

1222906

MRGBP
MRG/MORF4L-binding protein

1

1

High-throughput

0.536

High

1222908

MED27
Mediator of RNA polymerase II transcription subunit 27

1

2

High-throughput

0.536

High

1222847

MED26
Mediator of RNA polymerase II transcription subunit 26

1

0

High-throughput

0.513

High

1222909

MED29
Mediator of RNA polymerase II transcription subunit 29

1

0

High-throughput

0.513

High

266903

PRGC1
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha

1

20

Small-scale

0.501

High

923316

ARNT
Aryl hydrocarbon receptor nuclear translocator

1

20

Small-scale

0.500

High

1021543

EPAS1
Endothelial PAS domain-containing protein 1

1

20

Small-scale

0.500

High

59067

CDC27
Cell division cycle protein 27 homolog

1

16

High-throughput

0.479

High

59743

SKT
Sickle tail protein

1

2

High-throughput

0.479

High

59866

MGAP
MAX gene-associated protein

1

5

High-throughput

0.479

High

60464

KANL3
KAT8 regulatory NSL complex subunit 3

1

2

High-throughput

0.479

High

67207

WDR76
WD repeat-containing protein 76

1

13

High-throughput

0.479

High

73071

ZN462
Zinc finger protein 462

1

12

High-throughput

0.479

High

73916

B2RQG2
PHD finger protein 3

1

9

High-throughput

0.479

High

86370

B9EKQ3
PR domain zinc finger protein 2

1

13

High-throughput

0.479

High

97790

PRR12
Proline-rich protein 12

1

20

High-throughput

0.479

High

97800

ASCC3
Activating signal cointegrator 1 complex subunit 3

1

18

High-throughput

0.479

High

98094

SETD2
Histone-lysine N-methyltransferase SETD2

1

20

High-throughput

0.479

High

98167

E9Q6A7
Bromodomain PHD finger transcription factor

1

20

High-throughput

0.479

High

98210

E9Q7C1
Mediator of RNA polymerase II transcription subunit 15

1

20

High-throughput

0.479

High

98291

E9QAP7
TATA-box binding protein associated factor 4

1

20

High-throughput

0.479

High

107470

F8WI37
Histone-lysine N-methyltransferase 2C

1

20

High-throughput

0.479

High

109285

G5E8K8
AHNAK nucleoprotein

1

2

High-throughput

0.479

High

205225

FOG1
Zinc finger protein ZFPM1

1

12

High-throughput

0.479

High

266700

ZN143
Zinc finger protein 143

1

14

High-throughput

0.479

High

312037

ZN326
DBIRD complex subunit ZNF326

1

9

High-throughput

0.479

High

312871

CTBP1
C-terminal-binding protein 1

1

7

High-throughput

0.479

High

482134

JUNB
Transcription factor JunB

1

16

High-throughput

0.479

High

543030

CDK1
Cyclin-dependent kinase 1

1

5

High-throughput

0.479

High

659101

XRCC6
X-ray repair cross-complementing protein 6

1

13

High-throughput

0.479

High

778146

RL18
Large ribosomal subunit protein eL18

1

1

High-throughput

0.479

High

976184

RPB7
DNA-directed RNA polymerase II subunit RPB7

1

2

High-throughput

0.479

High

983370

RS28
Small ribosomal subunit protein eS28

1

2

High-throughput

0.479

High

1023496

RLA2
Large ribosomal subunit protein P2

1

1

High-throughput

0.479

High

1028512

HNRL2
Heterogeneous nuclear ribonucleoprotein U-like protein 2

1

20

High-throughput

0.479

High

1062937

LYAR
Cell growth-regulating nucleolar protein

1

2

High-throughput

0.479

High

1189698

FUBP2
Far upstream element-binding protein 2

1

15

High-throughput

0.479

High

1190050

RREB1
Ras-responsive element-binding protein 1

1

18

High-throughput

0.479

High

1190056

Q3UH28
Zinc finger, MYND-type containing 8

1

20

High-throughput

0.479

High

1190549

Q3UM65
Runt-related transcription factor

1

2

High-throughput

0.479

High

1190988

KDM5A
Lysine-specific demethylase 5A

1

16

High-throughput

0.479

High

1196050

ATAD5
ATPase family AAA domain-containing protein 5

1

19

High-throughput

0.479

High

1222821

EWS
RNA-binding protein EWS

1

13

High-throughput

0.479

High

1222822

HIRA
Protein HIRA

1

20

High-throughput

0.479

High

1222823

CTR9
RNA polymerase-associated protein CTR9 homolog

1

20

High-throughput

0.479

High

1222825

CCNC
Cyclin-C

1

16

High-throughput

0.479

High

1222830

INT1
Integrator complex subunit 1

1

1

High-throughput

0.479

High

1222832

DHX57
Putative ATP-dependent RNA helicase DHX57

1

12

High-throughput

0.479

High

1222833

Q6P5E3
Sal-like protein 1

1

15

High-throughput

0.479

High

1222834

MBTD1
MBT domain-containing protein 1

1

6

High-throughput

0.479

High

1222837

INT6
Integrator complex subunit 6

1

2

High-throughput

0.479

High

1222841

MED16
Mediator of RNA polymerase II transcription subunit 16

1

4

High-throughput

0.479

High

1222843

NFRKB
Nuclear factor related to kappa-B-binding protein

1

20

High-throughput

0.479

High

1222845

KDM1A
Lysine-specific histone demethylase 1A

1

8

High-throughput

0.479

High

1222846

SPOP
Speckle-type POZ protein

1

10

High-throughput

0.479

High

1222849

INT7
Integrator complex subunit 7

1

2

High-throughput

0.479

High

1222852

Q80ZH7
DNA ligase

1

4

High-throughput

0.479

High

1222854

ZN592
Zinc finger protein 592

1

11

High-throughput

0.479

High

1222855

CSTF2
Cleavage stimulation factor subunit 2

1

20

High-throughput

0.479

High

1222858

EXOS6
Exosome complex component MTR3

1

12

High-throughput

0.479

High

1222869

P66A
Transcriptional repressor p66 alpha

1

6

High-throughput

0.479

High

1222871

INT9
Integrator complex subunit 9

1

7

High-throughput

0.479

High

1222872

INT10
Integrator complex subunit 10

1

2

High-throughput

0.479

High

1222874

ARP8
Actin-related protein 8

1

20

High-throughput

0.479

High

1222879

Q8VD35
Orthodenticle homeobox 2

1

6

Small-scale

0.479

High

1222880

ELF5
ETS-related transcription factor Elf-5

1

9

High-throughput

0.479

High

1222887

EED
Polycomb protein EED

1

20

High-throughput

0.479

High

1222888

SMTN
Smoothelin

1

20

High-throughput

0.479

High

1222894

ZN281
Zinc finger protein 281

1

20

High-throughput

0.479

High

1222895

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

9

High-throughput

0.479

High

1222898

RING2
E3 ubiquitin-protein ligase RING2

1

17

Small-scale

0.479

High

1222902

ZN655
Zinc finger protein 655

1

12

High-throughput

0.479

High

1222904

ZN687
Zinc finger protein 687

1

15

High-throughput

0.479

High

1222905

MED8
Mediator of RNA polymerase II transcription subunit 8

1

4

High-throughput

0.479

High

1222910

AKAP8
A-kinase anchor protein 8

1

9

High-throughput

0.479

High

1222911

SENP3
Sentrin-specific protease 3

1

5

High-throughput

0.479

High

1222912

SYNCI
Syncoilin

1

20

High-throughput

0.479

High

1222916

HIC2
Hypermethylated in cancer 2 protein

1

20

High-throughput

0.479

High

1222917

CAF1A
Chromatin assembly factor 1 subunit A

1

20

High-throughput

0.479

High

1222919

TFEB
Transcription factor EB

1

9

High-throughput

0.479

High

1222921

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

16

High-throughput

0.479

High

1222828

UTF1
Undifferentiated embryonic cell transcription factor 1

1

0

High-throughput

0.458

High

51272

A1L3S7
GATA zinc finger domain containing 2B

1

6

High-throughput

0.445

High

1021839

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

3

High-throughput

0.445

High

1222839

KMT2D
Histone-lysine N-methyltransferase 2D

1

20

High-throughput

0.445

High

1222848

Q7TQE1
Mediator of RNA polymerase II transcription subunit 15

1

20

High-throughput

0.445

High

1222856

KMT2C
Histone-lysine N-methyltransferase 2C

1

20

High-throughput

0.445

High

1222857

PB1
Protein polybromo-1

1

20

High-throughput

0.445

High

1222892

Q99JW7
Cdc2a protein

1

5

High-throughput

0.445

High

1222913

SALL1
Sal-like protein 1

1

15

High-throughput

0.445

High

59973

LAS1L
Ribosomal biogenesis protein LAS1L

1

2

High-throughput

0.437

High

107164

F8VQD1
Protein polybromo-1

1

20

High-throughput

0.437

High

107463

F8WGW3
S1 RNA-binding domain-containing protein 1

1

5

High-throughput

0.437

High

1021254

FRG1
Protein FRG1

1

2

High-throughput

0.437

High

1189679

NOL9
Polynucleotide 5'-hydroxyl-kinase NOL9

1

4

High-throughput

0.437

High

1221163

XRCC1
DNA repair protein XRCC1

1

1

High-throughput

0.437

High

1222829

MD13L
Mediator of RNA polymerase II transcription subunit 13-like

1

5

High-throughput

0.437

High

1222831

RRP12
RRP12-like protein

1

2

High-throughput

0.437

High

1222838

SMRC2
SWI/SNF complex subunit SMARCC2

1

20

High-throughput

0.437

High

1222842

GNL3L
Guanine nucleotide-binding protein-like 3-like protein

1

9

High-throughput

0.437

High

1222861

SREK1
Splicing regulatory glutamine/lysine-rich protein 1

1

16

High-throughput

0.437

High

1222865

RCOR1
REST corepressor 1

1

20

High-throughput

0.437

High

1222891

MRM1
rRNA methyltransferase 1, mitochondrial

1

6

High-throughput

0.437

High

1222920

SKP1
S-phase kinase-associated protein 1

1

1

High-throughput

0.437

High

1222923

HNRPF
Heterogeneous nuclear ribonucleoprotein F

1

20

High-throughput

0.437

High

107952

G3UW74
Mediator of RNA polymerase II transcription subunit 16

1

4

High-throughput

0.407

High

148414

O08847
DNA-directed RNA polymerase subunit

1

6

High-throughput

0.407

High

1222827

Q6GQS5
Mediator of RNA polymerase II transcription subunit 13

1

5

High-throughput

0.407

High

1222835

Q6P6A2
Cyclin-C

1

16

High-throughput

0.407

High

1222907

Q9DAY7
Mediator of RNA polymerase II transcription subunit 8

1

4

High-throughput

0.407

High

607809

HXK1
Hexokinase-1

1

0

High-throughput

0.249

Low

1201669

LITD1
LINE-1 type transposase domain-containing protein 1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025