HitPredict

Interactor 1: PDCD6 (P12815)
Programmed cell death protein 6 (ALG-257) (Apoptosis-linked gene 2 protein) (ALG-2) (PMP41)
Gene: PDCD6

Interactor 2: PDC6I (Q9WU78)
Programmed cell death 6-interacting protein (ALG-2-interacting protein 1) (ALG-2-interacting protein X) (E2F1-inducible protein) (Eig2)
Gene: Pdcd6ip

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.562

Property	Details
Experiments	17889823, 10744743
Identification Methods	pull down, two hybrid
Interaction Type	association, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005768 - endosome GO:0005829 - cytosol GO:0006915 - apoptotic process GO:0046983 - protein dimerization activity
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 191 Mm			1 869
+	Hs
		259760 PDCD6_HUMAN (1-191): 4.07e-48: 156: 98.95		PDC6I_HUMAN (1-869): 0: 787: 94.36
+	Dm
		1179294 Q7K2L7_DROME (16-188): 9.98e-50: 161: 38.73		Q9VB05_DROME (1-869): 0: 646: 40.85
+	Dm
		69085 A8Y589_DROME (89-190): 1.03e-16: 75.6: 26.21		Q9VB05_DROME (1-869): 0: 646: 40.85
+	Hs
		259784 PDCD6_HUMAN (1-191): 4.07e-48: 156: 98.95		PTN23_HUMAN (3-869): 1.18e-168: 533: 23.93
+	Sc
		764102 PEF1_YEAST (20-188): 3.68e-51: 169: 25.86		RV167_YEAST (429-828): 1.57e-28: 122: 14.32
+	Hs
		160213 PEF1_HUMAN (4-191): 4.02e-45: 152: 39.15		HGS_HUMAN (550-863): 3.74e-27: 120: 18.10
+	Dm
		1373832 CANB_DROME (7-188): 1.33e-48: 170: 26.06		CANB_DROME (676-819): 7.33e-14: 78: 17.31
+	Hs
		427921 CAN1_HUMAN (19-188): 3.19e-51: 176: 22.58		WDR33_HUMAN (671-867): 4.66e-10: 65.7: 13.33
+	Hs
		259669 PDCD6_HUMAN (1-191): 4.07e-48: 156: 98.95		SC31A_HUMAN (671-868): 1e-09: 64.5: 14.93
+	Hs
		302329 PEF1_HUMAN (4-191): 4.02e-45: 152: 39.15		SC31A_HUMAN (671-868): 1e-09: 64.5: 14.93
+	Dm
		1014697 CANA_DROME (60-184): 3.95e-16: 77.4: 28.80		CANB_DROME (676-819): 7.33e-14: 78: 17.31