HitPredict

Interactor 1: CADH1 (P12830)
Cadherin-1 (CAM 120/80) (Epithelial cadherin) (E-cadherin) (Uvomorulin) (CD antigen CD324) [Cleaved into: E-Cad/CTF1; E-Cad/CTF2; E-Cad/CTF3]
Gene: CDH1

Interactor 2: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	18057010
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane GO:0034332 - adherens junction organization GO:0070062 - extracellular exosome GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 882 Hs			1 191
+	Hs
		521840 CADH1_HUMAN (1-882): 0: 836: 100.00		RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48
+	Hs
		580261 CADH2_HUMAN (28-881): 0: 769: 45.86		RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17
+	Hs
		580220 CADH2_HUMAN (28-881): 0: 769: 45.86		RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31
+	Hs
		580224 CADH2_HUMAN (28-881): 0: 769: 45.86		RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73
+	Hs
		545200 CADH2_HUMAN (28-881): 0: 769: 45.86		RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75
+	Hs
		436153 CADH2_HUMAN (28-881): 0: 769: 45.86		RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41
+	Hs
		580218 CADH2_HUMAN (28-881): 0: 769: 45.86		RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32
+	Hs
		606304 CADH3_HUMAN (3-882): 0: 716: 53.06		RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48
+	Hs
		564530 DSC3_HUMAN (2-874): 0: 655: 27.92		RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94
+	Hs
		564486 DSC2_HUMAN (33-874): 0: 652: 27.88		RHOQ_HUMAN (4-187): 7.35e-91: 266: 67.94
+	Hs
		1055855 DSC3_HUMAN (2-874): 0: 655: 27.92		RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17
+	Hs
		925210 DSC2_HUMAN (33-874): 0: 652: 27.88		RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31
+	Hs
		894012 DSC3_HUMAN (2-874): 0: 655: 27.92		CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00
+	Hs
		893916 DSC2_HUMAN (33-874): 0: 652: 27.88		CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00
+	Hs
		900472 DSC3_HUMAN (2-874): 0: 655: 27.92		RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48
+	Hs
		900393 DSC2_HUMAN (33-874): 0: 652: 27.88		RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48
+	Hs
		545331 DSC2_HUMAN (33-874): 0: 652: 27.88		RAC2_HUMAN (1-191): 1.49e-80: 239: 68.75
+	Hs
		436262 DSC2_HUMAN (33-874): 0: 652: 27.88		RHOC_HUMAN (5-191): 3.64e-79: 235: 52.41
+	Hs
		892326 DSC2_HUMAN (33-874): 0: 652: 27.88		RAC3_HUMAN (1-177): 2.36e-78: 233: 72.32
+	Hs
		1055834 DSC3_HUMAN (2-874): 0: 655: 27.92		RHOU_HUMAN (4-186): 1.03e-72: 221: 58.82