HitPredict

Interactor 1: CADH1 (P12830)
Cadherin-1 (CAM 120/80) (Epithelial cadherin) (E-cadherin) (Uvomorulin) (CD antigen CD324) [Cleaved into: E-Cad/CTF1; E-Cad/CTF2; E-Cad/CTF3]
Gene: CDH1

Interactor 2: PTPRJ (Q12913)
Receptor-type tyrosine-protein phosphatase eta (Protein-tyrosine phosphatase eta) (R-PTP-eta) (EC 3.1.3.48) (Density-enhanced phosphatase 1) (DEP-1) (HPTP eta) (Protein-tyrosine phosphatase receptor type J) (R-PTP-J) (CD antigen CD148)
Gene: PTPRJ

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25468996
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0008013 - beta-catenin binding GO:0030336 - negative regulation of cell migration GO:0045295 - gamma-catenin binding GO:0045296 - cadherin binding and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 882 Hs			1 1337
+	Hs
		580229 CADH2_HUMAN (28-881): 0: 769: 45.86		PTPRJ_HUMAN (1-1337): 0: 925: 100.00
+	Hs
		521907 CADH1_HUMAN (1-882): 0: 836: 100.00		PTPRS_HUMAN (6-974): 1.34e-95: 341: 11.86
+	Hs
		489891 CADH1_HUMAN (1-882): 0: 836: 100.00		PTPRF_HUMAN (189-971): 2.78e-83: 303: 14.68
+	Hs
		576981 CADH2_HUMAN (28-881): 0: 769: 45.86		PTPRA_HUMAN (521-1304): 2.08e-110: 368: 19.78
+	Hs
		521727 CADH1_HUMAN (1-882): 0: 836: 100.00		PTPRD_HUMAN (194-1091): 2.82e-80: 294: 12.49
+	Mm
		454937 CADH1_MOUSE (1-882): 0: 799: 81.45		PTPRQ_MOUSE (74-1096): 7.76e-72: 268: 12.33
+	Hs
		521728 CADH1_HUMAN (1-882): 0: 836: 100.00		PTPRG_HUMAN (757-1329): 3.11e-55: 213: 17.43
+	Hs
		521713 CADH1_HUMAN (1-882): 0: 836: 100.00		PTN1_HUMAN (1033-1290): 1.72e-55: 201: 36.84
+	Mm
		472760 CADH2_MOUSE (28-881): 0: 762: 46.43		PTPRQ_MOUSE (74-1096): 7.76e-72: 268: 12.33
+	Hs
		580201 CADH2_HUMAN (28-881): 0: 769: 45.86		PTPRG_HUMAN (757-1329): 3.11e-55: 213: 17.43
+	Hs
		521743 CADH1_HUMAN (1-882): 0: 836: 100.00		PTPRM_HUMAN (24-416): 6.07e-30: 131: 12.78
+	Hs
		616974 DSC3_HUMAN (2-874): 0: 655: 27.92		PTPRD_HUMAN (194-1091): 2.82e-80: 294: 12.49
+	Hs
		580235 CADH2_HUMAN (28-881): 0: 769: 45.86		PTPRK_HUMAN (25-498): 4.41e-30: 132: 12.10
+	Mm
		454946 CADH1_MOUSE (1-882): 0: 799: 81.45		PTPRM_MOUSE (114-507): 2.59e-17: 90.5: 11.66
+	Hs
		580200 CADH2_HUMAN (28-881): 0: 769: 45.86		PTPRB_HUMAN (463-930): 1.38e-23: 111: 16.63
+	Hs
		580238 CADH2_HUMAN (28-881): 0: 769: 45.86		PTPRO_HUMAN (46-453): 1.96e-21: 103: 14.92
+	Hs
		441173 CADH2_HUMAN (28-881): 0: 769: 45.86		PTPRC_HUMAN (47-298): 3.49e-10: 67: 9.89
+	Hs
		573632 CAD13_HUMAN (8-701): 0: 633: 36.20		PTN1_HUMAN (1033-1290): 1.72e-55: 201: 36.84
+	Hs
		490028 PCDBG_HUMAN (376-868): 1.94e-73: 258: 16.96		PTPRF_HUMAN (189-971): 2.78e-83: 303: 14.68
+	Hs
		617023 PCDBG_HUMAN (376-868): 1.94e-73: 258: 16.96		PTPRD_HUMAN (194-1091): 2.82e-80: 294: 12.49