HitPredict

Interactor 1: CADH1 (P12830)
Cadherin-1 (CAM 120/80) (Epithelial cadherin) (E-cadherin) (Uvomorulin) (CD antigen CD324) [Cleaved into: E-Cad/CTF1; E-Cad/CTF2; E-Cad/CTF3]
Gene: CDH1

Interactor 2: LIMA1 (Q9UHB6)
LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm)
Gene: LIMA1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	25468996, 18093941
Identification Methods	proximity labelling technology, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0015629 - actin cytoskeleton GO:0045296 - cadherin binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 882 Hs			1 759
+	Mm
		454961 CADH1_MOUSE (1-882): 0: 799: 81.45		LIMA1_MOUSE (1-759): 0: 826: 75.92
+	Hs
		522060 CADH1_HUMAN (1-882): 0: 836: 100.00		MILK1_HUMAN (355-540): 3.05e-31: 133: 21.81
+	Hs
		150511 CADH1_HUMAN (1-882): 0: 836: 100.00		ABLM1_HUMAN (298-548): 8.97e-23: 106: 11.28
+	Hs
		521802 CADH1_HUMAN (1-882): 0: 836: 100.00		PAXI_HUMAN (268-446): 5.9e-14: 77.3: 14.53
+	Hs
		521936 CADH1_HUMAN (1-882): 0: 836: 100.00		LASP1_HUMAN (390-480): 2.66e-11: 66.8: 25.00