Interactor 1: PEP5 (P12868)
E3 ubiquitin-protein ligase PEP5 (EC 2.3.2.27) (Carboxypeptidase Y-deficient protein 5) (Histone E3 ligase PEP5) (RING-type E3 ubiquitin transferase PEP5) (Vacuolar biogenesis protein END1) (Vacuolar morphogenesis protein 1) (Vacuolar protein sorting-associated protein 11) (Vacuolar protein-targeting protein 11)
Gene: PEP5

Interactor 2: VPS33 (P20795)
Vacuolar protein sorting-associated protein 33 (Protein SLP1) (Vacuolar morphogenesis protein 5)
Gene: VPS33

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 0.60 0.757

The method score is based on:

Property Details
Experiments 9362071, 11694574, 10944212, 16429126, 21325627, 20604902, 15889152, 16601699, 18385512, 37968396, 22940862
Identification Methods cross-linking study, affinity chromatography technology, pull down, two hybrid, biochemical, anti bait coimmunoprecipitation, tandem affinity purification
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000329 - fungal-type vacuole membrane
GO:0005829 - cytosol
GO:0006886 - intracellular protein transport
GO:0007033 - vacuole organization
GO:0030897 - HOPS complex
and 6 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 1029
Sc

1 691
+ Rn
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024