HitPredict

Interactor 1: PSA1 (P12881)
Proteasome subunit alpha type-1 (PROS-Dm35) (Proteasome 35 kDa subunit)
Gene: Prosalpha6

Interactor 2: PSMD7 (P26270)
26S proteasome non-ATPase regulatory subunit 7 (26S proteasome regulatory subunit RPN8) (26S proteasome regulatory subunit S12) (Proteasome subunit p39B) (Proteasome subunit p40) (Protein Mov34)
Gene: Rpn8

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22036573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000502 - proteasome complex GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 279 Dm			1 338
+	Dm
		611629 PSA71_DROME (4-236): 4.09e-102: 299: 30.93		PSMD7_DROME (1-338): 4.57e-136: 391: 100.00
+	Dm
		640776 PSA5_DROME (1-240): 3.68e-93: 276: 28.11		PSMD7_DROME (1-338): 4.57e-136: 391: 100.00
+	Hs
		637362 PSA1_HUMAN (1-269): 8.96e-103: 302: 52.42		PSMD7_HUMAN (4-288): 8.69e-104: 309: 81.75
+	Mm
		643130 PSA1_MOUSE (1-269): 1.85e-101: 298: 52.79		PSMD7_MOUSE (4-288): 2.12e-103: 308: 81.75
+	Hs
		656177 PSA5_HUMAN (1-239): 7.88e-95: 280: 30.08		PSMD7_HUMAN (4-288): 8.69e-104: 309: 81.75
+	Hs
		849173 PSA6_HUMAN (1-243): 1.35e-92: 275: 29.48		PSMD7_HUMAN (4-288): 8.69e-104: 309: 81.75
+	Hs
		638089 PSA4_HUMAN (1-236): 2.86e-90: 270: 29.22		PSMD7_HUMAN (4-288): 8.69e-104: 309: 81.75
+	Dm
		522502 PSA1_DROME (1-279): 9.24e-111: 322: 100.00		PSDE_DROME (2-273): 9.64e-61: 198: 16.89
+	Hs
		130746 PSA1_HUMAN (1-269): 8.96e-103: 302: 52.42		PSDE_HUMAN (2-275): 4.37e-61: 199: 16.78
+	Dm
		611650 PSA71_DROME (4-236): 4.09e-102: 299: 30.93		PSDE_DROME (2-273): 9.64e-61: 198: 16.89
+	Sc
		771356 PSA6_YEAST (1-236): 5.86e-67: 209: 46.64		RPN8_YEAST (9-312): 1.24e-91: 278: 46.27
+	Hs
		130754 PSA5_HUMAN (1-239): 7.88e-95: 280: 30.08		PSDE_HUMAN (2-275): 4.37e-61: 199: 16.78
+	Sp
		784781 PSA5_SCHPO (1-242): 1.8e-94: 280: 32.40		RPN11_SCHPO (3-272): 2.41e-61: 199: 18.00
+	Hs
		130644 PSA7_HUMAN (6-237): 5.84e-94: 279: 37.02		PSDE_HUMAN (2-275): 4.37e-61: 199: 16.78
+	Sp
		145195 PSA6_SCHPO (1-266): 3.63e-93: 277: 46.99		RPN11_SCHPO (3-272): 2.41e-61: 199: 18.00
+	Dm
		1278634 PSA5_DROME (1-240): 3.68e-93: 276: 28.11		PSDE_DROME (2-273): 9.64e-61: 198: 16.89
+	Hs
		130824 PSA6_HUMAN (1-243): 1.35e-92: 275: 29.48		PSDE_HUMAN (2-275): 4.37e-61: 199: 16.78
+	Hs
		130749 PSA4_HUMAN (1-236): 2.86e-90: 270: 29.22		PSDE_HUMAN (2-275): 4.37e-61: 199: 16.78
+	Sp
		784767 PSA3_SCHPO (1-246): 1.82e-90: 270: 30.20		RPN11_SCHPO (3-272): 2.41e-61: 199: 18.00
+	Sp
		293712 PSA2_SCHPO (4-181): 1.14e-35: 129: 41.44		RPN11_SCHPO (3-272): 2.41e-61: 199: 18.00