HitPredict

Interactor 1: MYH1 (P12882)
Myosin-1 (Myosin heavy chain 1) (Myosin heavy chain 2x) (MyHC-2x) (Myosin heavy chain IIx/d) (MyHC-IIx/d) (Myosin heavy chain, skeletal muscle, adult 1)
Gene: MYH1

Interactor 2: HIF1A (Q16665)
Hypoxia-inducible factor 1-alpha (HIF-1-alpha) (HIF1-alpha) (ARNT-interacting protein) (Basic-helix-loop-helix-PAS protein MOP1) (Class E basic helix-loop-helix protein 78) (bHLHe78) (Member of PAS protein 1) (PAS domain-containing protein 8)
Gene: HIF1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1939 Hs			1 826
+	Hs
		1085739 MYH4_HUMAN (1-1939): 0: 1166: 94.07		HIF1A_HUMAN (1-826): 0: 741: 100.00
+	Hs
		1085714 MYH2_HUMAN (1-1939): 0: 1150: 94.38		HIF1A_HUMAN (1-826): 0: 741: 100.00
+	Hs
		528376 MYH6_HUMAN (3-1934): 0: 1140: 80.59		HIF1A_HUMAN (1-826): 0: 741: 100.00
+	Hs
		502916 MYH3_HUMAN (723-1598): 1.27e-43: 177: 15.58		HIF1A_HUMAN (1-826): 0: 741: 100.00
+	Dm
		1096484 MYSN_DROME (860-1938): 3.08e-58: 225: 16.91		SIMA_DROME (4-722): 1.28e-95: 329: 25.42
+	Hs
		649050 MYH10_HUMAN (1083-1938): 2.16e-54: 212: 15.35		ARNT_HUMAN (7-652): 5.14e-103: 338: 17.06
+	Hs
		649049 MYH9_HUMAN (1104-1938): 6.77e-54: 211: 16.02		ARNT_HUMAN (7-652): 5.14e-103: 338: 17.06
+	Hs
		725093 MYH9_HUMAN (1104-1938): 6.77e-54: 211: 16.02		NCOA3_HUMAN (1-746): 4.42e-98: 335: 15.31