HitPredict

Interactor 1: MYH7 (P12883)
Myosin-7 (Myosin heavy chain 7) (Myosin heavy chain slow isoform) (MyHC-slow) (Myosin heavy chain, cardiac muscle beta isoform) (MyHC-beta)
Gene: MYH7

Interactor 2: AURKC (Q9UQB9)
Aurora kinase C (EC 2.7.11.1) (Aurora 3) (Aurora/IPL1-related kinase 3) (ARK-3) (Aurora-related kinase 3) (Aurora/IPL1/Eg2 protein 2) (Serine/threonine-protein kinase 13) (Serine/threonine-protein kinase aurora-C)
Gene: AURKC

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 1935 Hs			1 309
+	Hs
		528359 MYH6_HUMAN (1-1932): 0: 1160: 92.71		KAPCB_HUMAN (6-308): 7.39e-133: 382: 28.80
+	Hs
		522582 MYH1_HUMAN (2-1935): 0: 1157: 80.90		AURKC_HUMAN (1-309): 6.63e-134: 383: 100.00
+	Hs
		522538 MYH1_HUMAN (2-1935): 0: 1157: 80.90		KAPCB_HUMAN (6-308): 7.39e-133: 382: 28.80
+	Hs
		1357872 MYH4_HUMAN (2-1935): 0: 1155: 80.54		AURKC_HUMAN (1-309): 6.63e-134: 383: 100.00
+	Hs
		610802 MYH4_HUMAN (2-1935): 0: 1155: 80.54		KAPCB_HUMAN (6-308): 7.39e-133: 382: 28.80
+	Hs
		610795 MYH2_HUMAN (2-1935): 0: 1147: 80.82		KAPCB_HUMAN (6-308): 7.39e-133: 382: 28.80
+	Hs
		725220 MYH10_HUMAN (26-1926): 0: 1000: 40.81		AURKB_HUMAN (3-305): 2.39e-134: 386: 76.39
+	Hs
		568568 MYH10_HUMAN (26-1926): 0: 1000: 40.81		KAPCA_HUMAN (6-308): 1.57e-133: 384: 29.75
+	Hs
		681696 MYH9_HUMAN (27-1926): 0: 981: 40.46		AKT1_HUMAN (5-309): 8.7e-134: 389: 29.47
+	Hs
		724962 MYH9_HUMAN (27-1926): 0: 981: 40.46		AURKB_HUMAN (3-305): 2.39e-134: 386: 76.39
+	Hs
		568567 MYH9_HUMAN (27-1926): 0: 981: 40.46		KAPCA_HUMAN (6-308): 1.57e-133: 384: 29.75
+	Hs
		528433 MYH8_HUMAN (730-1357): 1.07e-27: 125: 16.04		AURKC_HUMAN (1-309): 6.63e-134: 383: 100.00
+	Hs
		728503 MYH11_HUMAN (728-1366): 6.54e-27: 122: 18.25		AURKB_HUMAN (3-305): 2.39e-134: 386: 76.39
+	Hs
		728527 MYH11_HUMAN (728-1366): 6.54e-27: 122: 18.25		AURKC_HUMAN (1-309): 6.63e-134: 383: 100.00
+	Hs
		1189785 MYH14_HUMAN (778-1406): 2.71e-21: 104: 15.79		AURKB_HUMAN (3-305): 2.39e-134: 386: 76.39