HitPredict

Interactor 1: SRC (P12931)
Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)
Gene: SRC

Interactor 2: RHG01 (Q07960)
Rho GTPase-activating protein 1 (CDC42 GTPase-activating protein) (GTPase-activating protein rhoGAP) (Rho-related small GTPase protein activator) (Rho-type GTPase-activating protein 1) (p50-RhoGAP)
Gene: ARHGAP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	8253717
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0045296 - cadherin binding GO:0048471 - perinuclear region of cytoplasm GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 536 Hs			1 439
+	Hs
		523082 SRC_HUMAN (1-536): 0: 651: 100.00		PRUN2_HUMAN (4-222): 1.04e-71: 247: 26.48
+	Hs
		64648 SRC_HUMAN (1-536): 0: 651: 100.00		RHG32_HUMAN (180-433): 7.32e-64: 225: 21.56
+	Hs
		433430 YES_HUMAN (1-536): 0: 604: 73.85		PRUN2_HUMAN (4-222): 1.04e-71: 247: 26.48
+	Hs
		412279 FYN_HUMAN (1-536): 0: 598: 68.39		PRUN2_HUMAN (4-222): 1.04e-71: 247: 26.48
+	Hs
		64642 FYN_HUMAN (1-536): 0: 598: 68.39		RHG32_HUMAN (180-433): 7.32e-64: 225: 21.56
+	Hs
		147859 FYN_HUMAN (1-536): 0: 598: 68.39		RHG33_HUMAN (164-438): 1.47e-63: 224: 22.38
+	Mm
		763398 FYN_MOUSE (1-536): 0: 597: 68.58		RHG33_MOUSE (164-438): 3.43e-63: 222: 22.38
+	Hs
		411755 LCK_HUMAN (75-534): 0: 552: 58.48		RHG21_HUMAN (168-434): 3.18e-71: 246: 23.08
+	Hs
		433915 LYN_HUMAN (1-531): 0: 532: 52.44		PRUN2_HUMAN (4-222): 1.04e-71: 247: 26.48
+	Hs
		433814 LYN_HUMAN (1-531): 0: 532: 52.44		RHG21_HUMAN (168-434): 3.18e-71: 246: 23.08
+	Hs
		64641 LCK_HUMAN (75-534): 0: 552: 58.48		RHG32_HUMAN (180-433): 7.32e-64: 225: 21.56
+	Hs
		433879 LYN_HUMAN (1-531): 0: 532: 52.44		RHG12_HUMAN (196-432): 5.78e-66: 228: 22.92
+	Hs
		64643 LYN_HUMAN (1-531): 0: 532: 52.44		RHG32_HUMAN (180-433): 7.32e-64: 225: 21.56
+	Hs
		523225 SRC_HUMAN (1-536): 0: 651: 100.00		3BP1_HUMAN (242-402): 1.01e-20: 97.1: 38.42
+	Hs
		523026 SRC_HUMAN (1-536): 0: 651: 100.00		RHG17_HUMAN (242-405): 2.45e-19: 92.8: 32.73
+	Hs
		789111 FRK_HUMAN (58-528): 3.73e-178: 512: 48.57		BNIP2_HUMAN (4-228): 1.04e-71: 230: 29.46
+	Hs
		302630 YES_HUMAN (1-536): 0: 604: 73.85		FA13A_HUMAN (242-431): 1.18e-25: 112: 34.03
+	Hs
		442896 HCK_HUMAN (1-531): 0: 569: 55.22		3BP1_HUMAN (242-402): 1.01e-20: 97.1: 38.42
+	Hs
		411763 LCK_HUMAN (75-534): 0: 552: 58.48		RHG17_HUMAN (242-405): 2.45e-19: 92.8: 32.73
+	Hs
		846494 BLK_HUMAN (45-531): 1.62e-179: 516: 57.58		TAGAP_HUMAN (255-431): 2.56e-22: 101: 34.97