Protein: SEC23
Protein transport protein SEC23

Gene: SEC23
Organism: Saccharomyces cerevisiae S288C
Interactions: 150
UniProt ID: P15303

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0003400 - regulation of COPII vesicle coating
GO:0005096 - GTPase activator activity
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

582476

SEC24
Protein transport protein SEC24

21

18

Small-scale

0.990

High

582503

SFB2
SED5-binding protein 2

12

18

Small-scale

0.980

High

582459

SFB3
SED5-binding protein 3

9

18

Small-scale

0.973

High

582410

SAR1
Small COPII coat GTPase SAR1

8

14

Small-scale

0.968

High

582462

SEC31
Protein transport protein SEC31

5

6

Small-scale

0.927

High

582413

SEC22
Protein transport protein SEC22

3

1

Small-scale

0.834

High

582487

SEC16
COPII coat assembly protein SEC16

9

2

Small-scale

0.755

High

582515

GRH1
GRASP65 homolog protein 1

6

2

Small-scale

0.730

High

582417

BET1
Protein transport protein BET1

6

6

Small-scale

0.730

High

582516

SEC13
Protein transport protein SEC13

5

10

Small-scale

0.711

High

578761

HSC82
ATP-dependent molecular chaperone HSC82

5

4

High-throughput

0.650

High

582422

CDC48
Cell division control protein 48

3

3

Small-scale

0.640

High

582507

SED5
Integral membrane protein SED5

3

6

Small-scale

0.640

High

582432

EMP24
Endosomal protein P24B

2

15

Small-scale

0.624

High

582504

TMEDA
Endoplasmic reticulum vesicle protein 25

2

17

Small-scale

0.624

High

582404

SEC23
Protein transport protein SEC23

1

15

High-throughput

0.618

High

392150

HSP82
ATP-dependent molecular chaperone HSP82

4

4

High-throughput

0.617

High

522938

HSP71
Heat shock protein SSA1

4

8

High-throughput

0.608

High

582426

HRR25
Casein kinase I homolog HRR25

2

4

Small-scale

0.602

High

582530

TRS33
Trafficking protein particle complex subunit 33

2

0

Small-scale

0.591

High

582506

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

3

3

Small-scale

0.590

High

582482

EMP47
Protein EMP47

2

3

Small-scale

0.584

High

582421

BOS1
Protein transport protein BOS1

1

1

Small-scale

0.561

High

560642

KIN2
Serine/threonine-protein kinase KIN2

2

1

High-throughput

0.558

High

582407

BIP
Endoplasmic reticulum chaperone BiP

1

2

High-throughput

0.536

High

558552

CAF20
Cap-associated protein CAF20

2

1

High-throughput

0.533

High

582483

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

1

High-throughput

0.533

High

535973

SEC7
ADP-ribosylation factor guanine nucleotide-exchange factor SEC7

2

1

Small-scale

0.521

High

582428

HS104
Heat shock protein 104

2

4

High-throughput

0.521

High

525824

HSP72
Heat shock protein SSA2

2

8

High-throughput

0.504

High

543690

SSB1
Ribosome-associated molecular chaperone SSB1

2

8

High-throughput

0.504

High

582475

SSB2
Ribosome-associated molecular chaperone SSB2

2

8

High-throughput

0.504

High

582474

RSP5
E3 ubiquitin-protein ligase RSP5

1

5

Small-scale

0.489

High

432475

RL7A
Large ribosomal subunit protein uL30A

1

1

High-throughput

0.489

High

460942

LTE1
Guanine nucleotide exchange factor LTE1

1

1

High-throughput

0.489

High

582408

CSK22
Casein kinase II subunit alpha'

1

1

High-throughput

0.489

High

582411

DBF2
Cell cycle protein kinase DBF2

1

2

High-throughput

0.489

High

582427

XPO1
Exportin-1

1

10

High-throughput

0.489

High

582441

NNK1
Nitrogen network kinase 1

1

1

High-throughput

0.489

High

582465

SSN3
Meiotic mRNA stability protein kinase SSN3

1

2

High-throughput

0.489

High

582481

RL10
Large ribosomal subunit protein uL16

1

1

High-throughput

0.489

High

376265

YPT1
GTP-binding protein YPT1

1

2

High-throughput

0.479

High

458526

SEC4
Ras-related protein SEC4

1

4

High-throughput

0.479

High

564697

ATC1
Calcium-transporting ATPase 1

1

3

High-throughput

0.479

High

582412

SLY1
Protein SLY1

1

2

High-throughput

0.479

High

582416

VPS34
Phosphatidylinositol 3-kinase VPS34

1

1

High-throughput

0.479

High

582419

KC11
Casein kinase I homolog 1

1

6

High-throughput

0.479

High

582425

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

582431

SEC17
Alpha-soluble NSF attachment protein

1

1

High-throughput

0.479

High

582433

PEP12
Syntaxin PEP12

1

4

High-throughput

0.479

High

582434

SSO1
Protein SSO1

1

4

High-throughput

0.479

High

582435

SMY2
Protein SMY2

1

1

High-throughput

0.479

High

582437

YPT7
Ypt/Rab-type GTPase YPT7

1

7

High-throughput

0.479

High

582439

CASP
Protein CASP

1

3

High-throughput

0.479

High

582442

VPS21
Vacuolar protein sorting-associated protein 21

1

7

High-throughput

0.479

High

582443

YPT52
GTP-binding protein YPT52

1

5

High-throughput

0.479

High

582447

TVP38
Golgi apparatus membrane protein TVP38

1

1

High-throughput

0.479

High

582448

VPP2
V-type proton ATPase subunit a, Golgi isoform

1

1

High-throughput

0.479

High

582449

SFT2
Protein transport protein SFT2

1

1

High-throughput

0.479

High

582451

ATG8
Autophagy-related protein 8

1

17

High-throughput

0.479

High

582453

YPT31
GTP-binding protein YPT31/YPT8

1

2

High-throughput

0.479

High

582455

GOSR1
Golgi SNAP receptor complex member 1

1

5

High-throughput

0.479

High

582457

RPN1
26S proteasome regulatory subunit RPN1

1

1

High-throughput

0.479

High

582460

SVP26
Protein SVP26

1

1

High-throughput

0.479

High

582463

AKR1
Palmitoyltransferase AKR1

1

2

High-throughput

0.479

High

582469

ATC3
Phospholipid-transporting ATPase DRS2

1

3

High-throughput

0.479

High

582471

ERV46
ER-derived vesicles protein ERV46

1

6

High-throughput

0.479

High

582472

SNF7
Vacuolar-sorting protein SNF7

1

4

High-throughput

0.479

High

582478

ATC7
Phospholipid-transporting ATPase NEO1

1

3

High-throughput

0.479

High

582480

SYS1
Protein SYS1

1

1

Small-scale

0.479

High

582484

ATG18
Autophagy-related protein 18

1

3

High-throughput

0.479

High

582485

SFT1
Protein transport protein SFT1

1

1

High-throughput

0.479

High

582492

YIP1
Protein transport protein YIP1

1

3

High-throughput

0.479

High

582497

PRA1
Prenylated Rab acceptor 1

1

1

High-throughput

0.479

High

582499

YIF1
Protein transport protein YIF1

1

2

High-throughput

0.479

High

582500

ATG2
Autophagy-related protein 2

1

1

High-throughput

0.479

High

582502

APJ1
J domain-containing protein APJ1

1

1

High-throughput

0.479

High

582509

SHR3
Secretory component protein SHR3

1

1

Small-scale

0.479

High

582512

TLG1
t-SNARE affecting a late Golgi compartment protein 1

1

8

High-throughput

0.479

High

582514

VTI1
t-SNARE VTI1

1

1

High-throughput

0.479

High

582517

ERP1
Protein ERP1

1

17

High-throughput

0.479

High

582523

ATG9
Autophagy-related protein 9

1

2

High-throughput

0.479

High

582525

EMP46
Protein EMP46

1

3

Small-scale

0.479

High

582526

YOP1
Protein YOP1

1

2

High-throughput

0.479

High

582415

VPS15
Serine/threonine-protein kinase VPS15

1

0

High-throughput

0.458

High

582436

VPS17
Vacuolar protein sorting-associated protein 17

1

0

High-throughput

0.458

High

582452

ATG14
Autophagy-related protein 14

1

0

High-throughput

0.458

High

582486

ATG27
Autophagy-related protein 27

1

0

High-throughput

0.458

High

582493

ATG1
Serine/threonine-protein kinase ATG1

1

0

High-throughput

0.458

High

582498

PDR17
Phosphatidylinositol transfer protein PDR17

1

0

Small-scale

0.458

High

582510

BECN1
Vacuolar protein sorting-associated protein 30

1

0

High-throughput

0.458

High

582520

ATG13
Autophagy-related protein 13

1

0

High-throughput

0.458

High

582522

ATG29
Autophagy-related protein 29

1

0

High-throughput

0.458

High

582528

ATG11
Autophagy-related protein 11

1

0

High-throughput

0.458

High

582409

PP11
Serine/threonine-protein phosphatase PP1-1

1

1

Small-scale

0.457

High

510149

HSP77
Import motor subunit, mitochondrial

1

2

High-throughput

0.445

High

582406

VATB
V-type proton ATPase subunit B

1

1

High-throughput

0.445

High

430765

ERF3
Eukaryotic peptide chain release factor GTP-binding subunit

1

3

Small-scale

0.437

High

582420

SIS1
Protein SIS1

1

2

High-throughput

0.437

High

582429

HOG1
Mitogen-activated protein kinase HOG1

1

1

High-throughput

0.437

High

582440

DEF1
RNA polymerase II degradation factor 1

1

1

High-throughput

0.437

High

582445

DID4
DOA4-independent degradation protein 4

1

3

High-throughput

0.437

High

582450

NU170
Nucleoporin NUP170

1

2

High-throughput

0.437

High

582454

FKS1
1,3-beta-glucan synthase component FKS1

1

1

High-throughput

0.437

High

582456

ECM29
Proteasome component ECM29

1

3

High-throughput

0.437

High

582461

RPN10
26S proteasome regulatory subunit RPN10

1

1

High-throughput

0.437

High

582464

MET30
F-box protein MET30

1

3

High-throughput

0.437

High

582467

DHH1
ATP-dependent RNA helicase DHH1

1

2

High-throughput

0.437

High

582470

LAA1
AP-1 accessory protein LAA1

1

2

High-throughput

0.437

High

582473

SS120
Protein SSP120

1

1

High-throughput

0.437

High

582490

NUP42
Nucleoporin NUP42

1

5

High-throughput

0.437

High

582491

SKP1
Suppressor of kinetochore protein 1

1

1

Small-scale

0.437

High

582494

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

1

High-throughput

0.437

High

582495

PESC
Pescadillo homolog

1

1

High-throughput

0.437

High

582505

DID2
Vacuolar protein-sorting-associated protein 46

1

3

High-throughput

0.437

High

582508

NU116
Nucleoporin NUP116/NSP116

1

5

High-throughput

0.437

High

582511

ESP1
Separin

1

1

High-throughput

0.437

High

582521

ATG23
Autophagy-related protein 23

1

1

High-throughput

0.437

High

582524

DBP10
ATP-dependent RNA helicase DBP10

1

1

High-throughput

0.437

High

381843

H4
Histone H4

1

2

High-throughput

0.407

High

394185

EF1A
Elongation factor 1-alpha

1

2

High-throughput

0.407

High

427119

RLA0
Large ribosomal subunit protein uL10

1

1

High-throughput

0.407

High

582424

RL5
Large ribosomal subunit protein uL18

1

1

High-throughput

0.407

High

582430

HSP7F
Heat shock protein homolog SSE1

1

10

High-throughput

0.407

High

582438

HSP78
Heat shock protein 78, mitochondrial

1

4

High-throughput

0.407

High

582458

SSZ1
Ribosome-associated complex subunit SSZ1

1

4

High-throughput

0.407

High

582468

YM11
Uncharacterized protein YMR124W

1

1

High-throughput

0.407

High

582489

RL4B
Large ribosomal subunit protein uL4B

1

2

High-throughput

0.407

High

454386

PHO4
Phosphate system positive regulatory protein PHO4

1

0

High-throughput

0.279

Low

557656

SRS2
ATP-dependent DNA helicase SRS2

1

0

High-throughput

0.279

Low

582488

CLA4
Serine/threonine-protein kinase CLA4

1

0

High-throughput

0.279

Low

582496

BUD32
EKC/KEOPS complex subunit BUD32

1

0

High-throughput

0.279

Low

582513

MUS81
Crossover junction endonuclease MUS81

1

0

High-throughput

0.279

Low

582414

RAD53
Serine/threonine-protein kinase RAD53

1

0

High-throughput

0.249

Low

582423

SPB4
ATP-dependent rRNA helicase SPB4

1

0

High-throughput

0.249

Low

582444

EAP1
Protein EAP1

1

0

High-throughput

0.249

Low

582446

LAS1
Protein LAS1

1

0

Small-scale

0.249

Low

582477

FIS1
Mitochondrial fission 1 protein

1

0

Small-scale

0.249

Low

582479

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

582501

IGO1
mRNA stability protein IGO1

1

0

Small-scale

0.249

Low

582518

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.249

Low

582519

ATG17
Autophagy-related protein 17

1

0

High-throughput

0.249

Low

582527

ATG31
Autophagy-related protein 31

1

0

High-throughput

0.249

Low

383485

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.232

Low

403335

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

0

High-throughput

0.232

Low

582405

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

0

High-throughput

0.232

Low

582418

RS3A2
Small ribosomal subunit protein eS1B

1

0

High-throughput

0.232

Low

582466

TCPB
T-complex protein 1 subunit beta

1

0

High-throughput

0.232

Low

582529

SET6
Potential protein lysine methyltransferase SET6

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025