HitPredict

Interactor 1: SRC (P12931)
Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)
Gene: SRC

Interactor 2: NMDE1 (Q12879)
Glutamate receptor ionotropic, NMDA 2A (GluN2A) (Glutamate [NMDA] receptor subunit epsilon-1) (N-methyl D-aspartate receptor subtype 2A) (NMDAR2A) (NR2A) (hNR2A)
Gene: GRIN2A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	12932824, 10458595
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0007611 - learning or memory GO:0009410 - response to xenobiotic stimulus GO:0043065 - positive regulation of apoptotic process GO:0097060 - synaptic membrane and 1 others more... GO:0098978 - glutamatergic synapse
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 536 Hs			1 1464
+	Hs
		412157 FYN_HUMAN (1-536): 0: 598: 68.39		NMDE1_HUMAN (1-1464): 0: 1763: 100.00
+	Mm
		403431 SRC_MOUSE (1-536): 0: 650: 98.13		NMDE2_MOUSE (4-1464): 0: 1534: 52.82
+	Hs
		412171 FYN_HUMAN (1-536): 0: 598: 68.39		NMDE2_HUMAN (4-1464): 0: 1550: 52.95
+	Mm
		403420 SRC_MOUSE (1-536): 0: 650: 98.13		NMDZ1_MOUSE (8-940): 0: 684: 23.20
+	Rn
		723636 SRC_RAT (1-536): 0: 644: 97.95		NMDZ1_RAT (8-940): 0: 685: 23.30
+	Hs
		412144 FYN_HUMAN (1-536): 0: 598: 68.39		NMDZ1_HUMAN (8-940): 0: 680: 23.30