HitPredict

Interactor 1: SRC (P12931)
Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)
Gene: SRC

Interactor 2: TRAF1 (Q13077)
TNF receptor-associated factor 1 (Epstein-Barr virus-induced protein 6)
Gene: TRAF1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	10635328, 15707590
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 536 Hs			1 416
+	Hs
		433335 YES_HUMAN (1-536): 0: 604: 73.85		TRAF2_HUMAN (3-415): 4e-124: 370: 38.01
+	Hs
		523227 SRC_HUMAN (1-536): 0: 651: 100.00		TRAF6_HUMAN (15-414): 1.57e-103: 318: 22.98
+	Mm
		403426 SRC_MOUSE (1-536): 0: 650: 98.13		TRAF6_MOUSE (15-414): 1.94e-101: 313: 22.51
+	Hs
		433514 YES_HUMAN (1-536): 0: 604: 73.85		TRAF6_HUMAN (15-414): 1.57e-103: 318: 22.98
+	Hs
		412424 FYN_HUMAN (1-536): 0: 598: 68.39		TRAF6_HUMAN (15-414): 1.57e-103: 318: 22.98
+	Hs
		337607 ABL1_HUMAN (47-536): 5.59e-169: 509: 40.00		TRAF6_HUMAN (15-414): 1.57e-103: 318: 22.98
+	Hs
		782838 CSK_HUMAN (84-525): 2.44e-172: 496: 39.16		TRAF6_HUMAN (15-414): 1.57e-103: 318: 22.98
+	Hs
		522953 SRC_HUMAN (1-536): 0: 651: 100.00		TRAF3_HUMAN (3-262): 9.64e-11: 65.3: 15.77
+	Hs
		846463 BLK_HUMAN (45-531): 1.62e-179: 516: 57.58		TRAF3_HUMAN (3-262): 9.64e-11: 65.3: 15.77
+	Mm
		729752 BTK_MOUSE (44-527): 7.13e-156: 461: 34.08		TRAF3_MOUSE (1-262): 2.34e-12: 70.7: 16.37