HitPredict

Interactor 1: SRC (P12931)
Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)
Gene: SRC

Interactor 2: FSD1 (Q9BTV5)
Fibronectin type III and SPRY domain-containing protein 1 (MID1-related protein 1) (Microtubule-associated protein GLFND)
Gene: FSD1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~fn3, SH2~fn3
Common GO terms	GO:0005737 - cytoplasm GO:0007049 - cell cycle
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 536 Hs			1 496
+	Hs
		433982 LYN_HUMAN (1-531): 0: 532: 52.44		FSD1L_HUMAN (4-495): 2.96e-138: 410: 60.16
+	Hs
		412363 FYN_HUMAN (1-536): 0: 598: 68.39		TRI39_HUMAN (9-481): 1.85e-102: 318: 15.37
+	Hs
		522983 SRC_HUMAN (1-536): 0: 651: 100.00		TRI25_HUMAN (3-469): 1.48e-78: 259: 18.49
+	Hs
		442893 HCK_HUMAN (1-531): 0: 569: 55.22		TRIM1_HUMAN (1-493): 3.48e-106: 334: 25.52
+	Hs
		523048 SRC_HUMAN (1-536): 0: 651: 100.00		TRI50_HUMAN (19-470): 3.84e-75: 246: 13.07
+	Hs
		433394 YES_HUMAN (1-536): 0: 604: 73.85		TRI67_HUMAN (1-486): 7e-89: 290: 22.29
+	Hs
		523138 SRC_HUMAN (1-536): 0: 651: 100.00		TRIM7_HUMAN (40-461): 7.53e-74: 243: 13.79
+	Hs
		411977 FYN_HUMAN (1-536): 0: 598: 68.39		TRI27_HUMAN (9-494): 1.06e-93: 295: 12.96
+	Hs
		433465 YES_HUMAN (1-536): 0: 604: 73.85		TRIM5_HUMAN (16-477): 4.89e-84: 269: 14.78
+	Hs
		442773 HCK_HUMAN (1-531): 0: 569: 55.22		TRI27_HUMAN (9-494): 1.06e-93: 295: 12.96
+	Hs
		846541 BLK_HUMAN (45-531): 1.62e-179: 516: 57.58		TRIM1_HUMAN (1-493): 3.48e-106: 334: 25.52
+	Hs
		337563 ABL1_HUMAN (47-536): 5.59e-169: 509: 40.00		TRI39_HUMAN (9-481): 1.85e-102: 318: 15.37
+	Hs
		789076 ABL2_HUMAN (11-536): 3.03e-170: 514: 39.03		TRI67_HUMAN (1-486): 7e-89: 290: 22.29
+	Hs
		782800 CSK_HUMAN (84-525): 2.44e-172: 496: 39.16		TRI67_HUMAN (1-486): 7e-89: 290: 22.29
+	Hs
		412294 FYN_HUMAN (1-536): 0: 598: 68.39		TRI63_HUMAN (4-161): 9.74e-50: 175: 27.04
+	Hs
		412344 FYN_HUMAN (1-536): 0: 598: 68.39		TRI55_HUMAN (1-163): 4.12e-32: 131: 21.95
+	Hs
		433933 LYN_HUMAN (1-531): 0: 532: 52.44		TRI63_HUMAN (4-161): 9.74e-50: 175: 27.04
+	Hs
		433984 LYN_HUMAN (1-531): 0: 532: 52.44		TRI55_HUMAN (1-163): 4.12e-32: 131: 21.95