Protein: DPB2
DNA polymerase epsilon subunit B (DNA polymerase II subunit 2)

Gene: DPB2
Organism: Saccharomyces cerevisiae S288C
Interactions: 78
UniProt ID: P24482

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006261 - DNA-templated DNA replication
GO:0008622 - epsilon DNA polymerase complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

642007

DPOE
DNA polymerase epsilon catalytic subunit A

25

4

Small-scale

0.991

High

665205

DPB4
DNA polymerase epsilon subunit D

8

1

Small-scale

0.748

High

665216

PSF1
DNA replication complex GINS protein PSF1

7

2

Small-scale

0.747

High

665209

CDC45
Cell division control protein 45

6

1

Small-scale

0.719

High

665164

DPB2
DNA polymerase epsilon subunit B

2

0

Small-scale

0.715

High

665169

DPB3
DNA polymerase epsilon subunit C

8

0

Small-scale

0.713

High

665189

CTF18
Chromosome transmission fidelity protein 18

5

1

Small-scale

0.709

High

665185

PSF2
DNA replication complex GINS protein PSF2

4

1

Small-scale

0.680

High

665200

SLD5
DNA replication complex GINS protein SLD5

4

1

Small-scale

0.676

High

665168

MRC1
Mediator of replication checkpoint protein 1

3

0

Small-scale

0.625

High

665197

CTF4
DNA polymerase alpha-binding protein

3

0

Small-scale

0.614

High

364348

CDK1
Cyclin-dependent kinase 1

2

0

Small-scale

0.612

High

665214

PSF3
DNA replication complex GINS protein PSF3

2

1

Small-scale

0.606

High

665190

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

2

0

High-throughput

0.595

High

664406

MCM3
DNA replication licensing factor MCM3

2

3

Small-scale

0.584

High

665172

MCM4
DNA replication licensing factor MCM4

2

4

Small-scale

0.584

High

665171

MCM5
Minichromosome maintenance protein 5

2

4

Small-scale

0.571

High

381411

H2B2
Histone H2B.2

2

0

High-throughput

0.563

High

561290

DPOLA
DNA polymerase alpha catalytic subunit A

1

4

Small-scale

0.553

High

525976

HSP72
Heat shock protein SSA2

2

1

High-throughput

0.552

High

543888

SSB1
Ribosome-associated molecular chaperone SSB1

2

1

High-throughput

0.552

High

665194

ORC1
Origin recognition complex subunit 1

1

1

High-throughput

0.515

High

665195

ORC4
Origin recognition complex subunit 4

1

1

High-throughput

0.515

High

403364

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

0

High-throughput

0.513

High

444428

DED1
ATP-dependent RNA helicase DED1

1

0

High-throughput

0.513

High

665204

KU80
ATP-dependent DNA helicase II subunit 2

1

0

High-throughput

0.513

High

632616

DBP4
ATP-dependent RNA helicase HCA4

1

0

High-throughput

0.493

High

665165

STE50
Protein STE50

1

0

High-throughput

0.493

High

665175

DOA1
Protein DOA1

1

0

High-throughput

0.493

High

665179

LSM12
Protein LSM12

1

0

High-throughput

0.493

High

665181

STM1
Suppressor protein STM1

1

0

High-throughput

0.493

High

665192

UTP22
U3 small nucleolar RNA-associated protein 22

1

0

High-throughput

0.493

High

665193

YG36
Uncharacterized protein YGR126W

1

0

High-throughput

0.493

High

665201

RPN4
Protein RPN4

1

0

High-throughput

0.493

High

665202

HMO1
High mobility group protein 1

1

0

High-throughput

0.493

High

665208

PBP4
Protein PBP4

1

0

High-throughput

0.493

High

665212

TMA46
Translation machinery-associated protein 46

1

0

High-throughput

0.493

High

665213

NOP53
Ribosome biogenesis protein NOP53

1

0

High-throughput

0.493

High

665217

RRP12
Ribosomal RNA-processing protein 12

1

0

High-throughput

0.493

High

665186

DPB11
DNA replication regulator DPB11

1

1

Small-scale

0.481

High

416862

CDC25
Cell division control protein 25

1

0

High-throughput

0.480

High

665174

SLD2
DNA replication regulator SLD2

1

1

Small-scale

0.479

High

665191

MCM6
DNA replication licensing factor MCM6

1

3

Small-scale

0.479

High

512014

RS4A
Small ribosomal subunit protein eS4A

1

0

High-throughput

0.458

High

647698

RFA1
Replication factor A protein 1

1

0

Small-scale

0.458

High

665170

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

665173

HOG1
Mitogen-activated protein kinase HOG1

1

0

Small-scale

0.458

High

665177

NSE2
E3 SUMO-protein ligase MMS21

1

0

Small-scale

0.458

High

665178

RRM3
ATP-dependent DNA helicase RRM3

1

0

Small-scale

0.458

High

665180

CTF8
Chromosome transmission fidelity protein 8

1

0

Small-scale

0.458

High

665183

NUG1
Nuclear GTP-binding protein NUG1

1

0

High-throughput

0.458

High

665196

SEN1
Helicase SEN1

1

0

Small-scale

0.458

High

665199

NOG1
Nucleolar GTP-binding protein 1

1

0

Small-scale

0.458

High

665203

SIZ1
E3 SUMO-protein ligase SIZ1

1

0

High-throughput

0.458

High

665206

CSM3
Chromosome segregation in meiosis protein 3

1

0

Small-scale

0.458

High

665207

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

665210

SMC5
Structural maintenance of chromosomes protein 5

1

0

Small-scale

0.458

High

394259

EF1A
Elongation factor 1-alpha

1

1

High-throughput

0.445

High

523126

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

531610

RL4A
Large ribosomal subunit protein uL4A

1

1

High-throughput

0.445

High

665184

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

665188

RL4B
Large ribosomal subunit protein uL4B

1

1

High-throughput

0.445

High

392272

HSP82
ATP-dependent molecular chaperone HSP82

1

0

High-throughput

0.426

High

592029

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.426

High

665166

MAS5
Mitochondrial protein import protein MAS5

1

0

High-throughput

0.426

High

665215

RL7B
Large ribosomal subunit protein uL30B

1

0

High-throughput

0.426

High

665167

DCC1
Sister chromatid cohesion protein DCC1

2

0

Small-scale

0.305

High

438383

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

0

High-throughput

0.269

Low

454198

LEUC
3-isopropylmalate dehydratase

1

0

High-throughput

0.269

Low

569549

CBS1
Cytochrome b translational activator protein CBS1, mitochondrial

1

0

High-throughput

0.269

Low

665176

MBA1
Inner membrane mitoribosome receptor MBA1, mitochondrial

1

0

High-throughput

0.269

Low

665182

IF4F2
Eukaryotic initiation factor 4F subunit p130

1

0

High-throughput

0.269

Low

665211

NOP12
Nucleolar protein 12

1

0

High-throughput

0.269

Low

665187

TRF5
Poly(A) RNA polymerase protein 1

1

0

Small-scale

0.251

Low

512272

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.249

Low

665198

UBC7
Ubiquitin-conjugating enzyme E2 7

1

0

High-throughput

0.238

Low

600982

RL8A
Large ribosomal subunit protein eL8A

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025