HitPredict

Interactor 1: XRCC6 (P12956)
X-ray repair cross-complementing protein 6 (EC 3.6.4.-) (EC 4.2.99.-) (5'-deoxyribose-5-phosphate lyase Ku70) (5'-dRP lyase Ku70) (70 kDa subunit of Ku antigen) (ATP-dependent DNA helicase 2 subunit 1) (ATP-dependent DNA helicase II 70 kDa subunit) (CTC box-binding factor 75 kDa subunit) (CTC75) (CTCBF) (DNA repair protein XRCC6) (Lupus Ku autoantigen protein p70) (Ku70) (Thyroid-lupus autoantigen) (TLAA) (X-ray repair complementing defective repair in Chinese hamster cells 6)
Gene: XRCC6

Interactor 2: TNIP1 (Q15025)
TNFAIP3-interacting protein 1 (A20-binding inhibitor of NF-kappa-B activation 1) (ABIN-1) (HIV-1 Nef-interacting protein) (Nef-associated factor 1) (Naf1) (Nip40-1) (Virion-associated nuclear shuttling protein) (VAN) (hVAN)
Gene: TNIP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36574265
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 609 Hs			1 636
+	Hs
		148340 XRCC6_HUMAN (1-609): 0: 666: 100.00		CTRO_HUMAN (51-557): 1.5e-16: 86.2: 14.12
+	Hs
		523555 XRCC6_HUMAN (1-609): 0: 666: 100.00		MYH10_HUMAN (210-571): 5.78e-13: 74.6: 10.48
+	Hs
		523554 XRCC6_HUMAN (1-609): 0: 666: 100.00		MYH9_HUMAN (267-566): 1.17e-09: 63.8: 13.33
+	Hs
		524932 XRCC5_HUMAN (31-609): 5.27e-125: 387: 16.77		TNIP1_HUMAN (1-636): 6.24e-78: 262: 100.00
+	Hs
		148341 XRCC5_HUMAN (31-609): 5.27e-125: 387: 16.77		CTRO_HUMAN (51-557): 1.5e-16: 86.2: 14.12