HitPredict

Interactor 1: IL7 (P13232)
Interleukin-7 (IL-7)
Gene: IL7

Interactor 2: IL2RG (P31785)
Cytokine receptor common subunit gamma (Interleukin-2 receptor subunit gamma) (IL-2 receptor subunit gamma) (IL-2R subunit gamma) (IL-2RG) (gammaC) (p64) (CD antigen CD132)
Gene: IL2RG

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.70 0.60 0.650

The method score is based on:

Property Details
Experiments 8128231, 9371812, 8266077
Identification Methods biochemical, fluorescent resonance energy transfer, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0019221 - cytokine-mediated signaling pathway
GO:0045579 - positive regulation of B cell differentiation
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 177
Hs

1 369
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024