HitPredict

Interactor 1: XRCC6 (P12956)
X-ray repair cross-complementing protein 6 (EC 3.6.4.-) (EC 4.2.99.-) (5'-deoxyribose-5-phosphate lyase Ku70) (5'-dRP lyase Ku70) (70 kDa subunit of Ku antigen) (ATP-dependent DNA helicase 2 subunit 1) (ATP-dependent DNA helicase II 70 kDa subunit) (CTC box-binding factor 75 kDa subunit) (CTC75) (CTCBF) (DNA repair protein XRCC6) (Lupus Ku autoantigen protein p70) (Ku70) (Thyroid-lupus autoantigen) (TLAA) (X-ray repair complementing defective repair in Chinese hamster cells 6)
Gene: XRCC6

Interactor 2: CD11A (Q9UQ88)
Cyclin-dependent kinase 11A (EC 2.7.11.22) (Cell division cycle 2-like protein kinase 2) (Cell division protein kinase 11A) (Galactosyltransferase-associated protein kinase p58/GTA) (PITSLRE serine/threonine-protein kinase CDC2L2)
Gene: CDK11A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30585729
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 609 Hs			1 783
+	Hs
		523518 XRCC6_HUMAN (1-609): 0: 666: 100.00		CD11B_HUMAN (1-783): 0: 559: 95.85
+	Hs
		523528 XRCC6_HUMAN (1-609): 0: 666: 100.00		CDK2_HUMAN (423-719): 9.55e-156: 456: 43.62
+	Hs
		414706 XRCC6_HUMAN (1-609): 0: 666: 100.00		CDK1_HUMAN (423-715): 6.59e-136: 405: 41.36
+	Hs
		523605 XRCC6_HUMAN (1-609): 0: 666: 100.00		CDK7_HUMAN (424-748): 1.27e-73: 245: 38.69
+	Hs
		524796 XRCC5_HUMAN (31-609): 5.27e-125: 387: 16.77		CDK2_HUMAN (423-719): 9.55e-156: 456: 43.62
+	Hs
		524843 XRCC5_HUMAN (31-609): 5.27e-125: 387: 16.77		CDK7_HUMAN (424-748): 1.27e-73: 245: 38.69