Protein: NSA2
Ribosome biogenesis protein NSA2 (NOP7-associated protein 2)

Gene: NSA2
Organism: Saccharomyces cerevisiae S288C
Interactions: 158
UniProt ID: P40078

Gene Ontology (top 5):
GO:0000460 - maturation of 5.8S rRNA
GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000466 - maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000470 - maturation of LSU-rRNA
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

818267

NOG1
Nucleolar GTP-binding protein 1

10

2

Small-scale

0.974

High

780271

EBP2
rRNA-processing protein EBP2

4

1

High-throughput

0.891

High

818292

NIP7
60S ribosome subunit biogenesis protein NIP7

2

1

High-throughput

0.793

High

818253

PESC
Pescadillo homolog

12

1

Small-scale

0.755

High

818256

NOG2
Nucleolar GTP-binding protein 2

11

5

Small-scale

0.754

High

782344

RPF2
Ribosome biogenesis protein RPF2

9

2

Small-scale

0.751

High

673568

NLE1
Ribosome assembly protein 4

8

2

Small-scale

0.750

High

818268

HAS1
ATP-dependent RNA helicase HAS1

8

2

Small-scale

0.747

High

816839

NUG1
Nuclear GTP-binding protein NUG1

7

5

Small-scale

0.742

High

818259

NOP15
Ribosome biogenesis protein 15

6

2

High-throughput

0.730

High

818236

RLP7
Ribosome biogenesis protein RLP7

6

3

Small-scale

0.729

High

750087

MRT4
Ribosome assembly factor MRT4

6

2

Small-scale

0.729

High

818270

ARX1
Probable metalloprotease ARX1

12

0

Small-scale

0.725

High

806614

RIX1
Pre-rRNA-processing protein RIX1

10

0

Small-scale

0.720

High

818284

BUD20
Bud site selection protein 20

7

0

Small-scale

0.716

High

814327

NOC2
Nucleolar complex protein 2

8

0

Small-scale

0.715

High

818252

CGR1
rRNA-processing protein CGR1

7

0

Small-scale

0.709

High

818237

NOP2
25S rRNA

5

2

Small-scale

0.709

High

682296

SPB4
ATP-dependent rRNA helicase SPB4

5

2

High-throughput

0.702

High

818301

IF6
Eukaryotic translation initiation factor 6

6

0

Small-scale

0.699

High

818283

RLP24
Ribosome biogenesis protein RLP24

5

2

Small-scale

0.699

High

791062

NOP4
Nucleolar protein 4

4

1

Small-scale

0.692

High

818274

ERB1
Ribosome biogenesis protein ERB1

4

2

Small-scale

0.691

High

804617

SSF1
Ribosome biogenesis protein SSF1

4

1

Small-scale

0.686

High

818250

NSA1
Ribosome biogenesis protein NSA1

5

0

Small-scale

0.678

High

818294

YTM1
Ribosome biogenesis protein YTM1

4

3

Small-scale

0.676

High

818249

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

4

0

High-throughput

0.660

High

818254

SDA1
Protein SDA1

4

0

Small-scale

0.658

High

570035

RL3
Large ribosomal subunit protein uL3

5

1

Small-scale

0.647

High

746631

DRS1
ATP-dependent RNA helicase DRS1

3

2

High-throughput

0.646

High

803869

CIC1
Proteasome-interacting protein CIC1

3

1

Small-scale

0.640

High

818299

DBP10
ATP-dependent RNA helicase DBP10

3

1

High-throughput

0.640

High

818243

ALB1
Ribosome biogenesis protein ALB1

3

0

Small-scale

0.628

High

818241

LOC1
60S ribosomal subunit assembly/export protein LOC1

3

0

High-throughput

0.618

High

818271

RRP17
Ribosomal RNA-processing protein 17

3

0

High-throughput

0.613

High

793484

MAK5
ATP-dependent RNA helicase MAK5

2

2

High-throughput

0.594

High

818296

MAK21
Ribosome biogenesis protein MAK21

2

2

High-throughput

0.594

High

410162

RL25
Large ribosomal subunit protein uL23

2

1

Small-scale

0.584

High

441936

RS14A
Small ribosomal subunit protein uS11A

2

1

High-throughput

0.584

High

512467

RS6A
Small ribosomal subunit protein eS6A

2

1

High-throughput

0.584

High

524091

HSP71
Heat shock protein SSA1

2

1

High-throughput

0.584

High

674654

RS2
Small ribosomal subunit protein uS5

2

1

High-throughput

0.584

High

689484

RS7A
Small ribosomal subunit protein eS7A

2

1

High-throughput

0.584

High

745084

AFG2
ATPase family gene 2 protein

2

2

Small-scale

0.584

High

763078

RRP1
Ribosomal RNA-processing protein 1

2

1

Small-scale

0.584

High

792074

GBLP
Small ribosomal subunit protein RACK1

2

3

High-throughput

0.584

High

818295

NOP53
Ribosome biogenesis protein NOP53

2

2

High-throughput

0.584

High

531758

RL4A
Large ribosomal subunit protein uL4A

2

2

Small-scale

0.571

High

818302

RRP12
Ribosomal RNA-processing protein 12

2

0

High-throughput

0.569

High

435126

RS3
Small ribosomal subunit protein uS3

2

0

High-throughput

0.559

High

435993

RS13
Small ribosomal subunit protein uS15

2

0

High-throughput

0.559

High

684742

RL5
Large ribosomal subunit protein uL18

2

0

Small-scale

0.559

High

795821

YBC8
UPF0642 protein YBL028C

2

0

Small-scale

0.559

High

818288

TMA16
Translation machinery-associated protein 16

2

0

Small-scale

0.559

High

805051

RPF1
Ribosome production factor 1

2

0

High-throughput

0.547

High

818272

PUF6
Pumilio homology domain family member 6

2

0

Small-scale

0.547

High

818247

RL4B
Large ribosomal subunit protein uL4B

1

2

High-throughput

0.536

High

455092

RS19A
Small ribosomal subunit protein eS19A

2

2

High-throughput

0.533

High

513035

RS8A
Small ribosomal subunit protein eS8A

2

1

High-throughput

0.533

High

747397

RSSA1
Small ribosomal subunit protein uS2A

2

1

High-throughput

0.533

High

753398

RS3A1
Small ribosomal subunit protein eS1A

2

2

High-throughput

0.533

High

818251

LSG1
Large subunit GTPase 1

2

5

Small-scale

0.533

High

818290

RS10A
Small ribosomal subunit protein eS10A

2

1

High-throughput

0.533

High

513870

RS11B
Small ribosomal subunit protein uS17B

1

0

High-throughput

0.517

High

448176

HAP2
Transcriptional activator HAP2

1

0

High-throughput

0.513

High

721976

XPO1
Exportin-1

1

0

High-throughput

0.513

High

149792

RS9A
Small ribosomal subunit protein uS4A

1

1

High-throughput

0.479

High

433670

RL26A
Large ribosomal subunit protein uL24A

1

2

High-throughput

0.479

High

435576

RS9B
Small ribosomal subunit protein uS4B

1

1

High-throughput

0.479

High

513692

RL2A
Large ribosomal subunit protein uL2A

1

3

High-throughput

0.479

High

534114

MAK16
Protein MAK16

1

1

High-throughput

0.479

High

677206

SPB1
27S pre-rRNA

1

2

High-throughput

0.479

High

689049

RL16A
Large ribosomal subunit protein uL13A

1

1

High-throughput

0.479

High

807080

FKBP3
Peptidyl-prolyl cis-trans isomerase

1

2

High-throughput

0.479

High

818245

RS7B
Small ribosomal subunit protein eS7B

1

1

High-throughput

0.479

High

818257

IPI3
Pre-rRNA-processing protein IPI3

1

3

High-throughput

0.479

High

818258

NOP13
Nucleolar protein 13

1

1

High-throughput

0.479

High

818261

RCM1
25S rRNA

1

2

High-throughput

0.479

High

818262

NOP3
Serine/arginine

1

7

High-throughput

0.479

High

818275

HRQ1
ATP-dependent helicase HRQ1

1

1

Small-scale

0.479

High

818277

FKBP4
FK506-binding protein 4

1

2

High-throughput

0.479

High

818278

JIP5
WD repeat-containing protein JIP5

1

3

High-throughput

0.479

High

818280

NOC4
Nucleolar complex protein 4

1

2

High-throughput

0.479

High

818282

NOC3
Nucleolar complex-associated protein 3

1

1

High-throughput

0.479

High

818285

NOP12
Nucleolar protein 12

1

4

High-throughput

0.479

High

818286

BRX1
Ribosome biogenesis protein BRX1

1

6

High-throughput

0.479

High

818291

RRS1
Regulator of ribosome biosynthesis

1

1

High-throughput

0.479

High

818293

MDN1
Midasin

1

1

High-throughput

0.479

High

818297

RL7B
Large ribosomal subunit protein uL30B

1

3

High-throughput

0.479

High

818231

NSA2
Ribosome biogenesis protein NSA2

1

0

Small-scale

0.460

High

436430

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

0

High-throughput

0.458

High

646419

RAD53
Serine/threonine-protein kinase RAD53

1

0

High-throughput

0.458

High

677932

YCQ6
Uncharacterized protein YCR016W

1

0

High-throughput

0.458

High

707224

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

780681

RRP14
Ribosomal RNA-processing protein 14

1

0

High-throughput

0.458

High

798501

REI1
Cytoplasmic 60S subunit biogenesis factor REI1

1

0

Small-scale

0.458

High

804989

IPI1
Pre-rRNA-processing protein IPI1

1

0

High-throughput

0.458

High

806132

NMD3
60S ribosomal export protein NMD3

1

0

Small-scale

0.458

High

809321

STM1
Suppressor protein STM1

1

0

High-throughput

0.458

High

813696

ECM1
Shuttling pre-60S factor ECM1

1

0

Small-scale

0.458

High

815402

RS26B
Small ribosomal subunit protein eS26B

1

0

High-throughput

0.458

High

816770

NOP16
Nucleolar protein 16

1

0

High-throughput

0.458

High

818232

RIO2
Serine/threonine-protein kinase RIO2

1

0

High-throughput

0.458

High

818233

BMT5
25S rRNA

1

0

High-throughput

0.458

High

818235

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

818240

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.458

High

818244

MTR4
ATP-dependent RNA helicase DOB1

1

0

Small-scale

0.458

High

818260

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.458

High

818264

ABF2
ARS-binding factor 2, mitochondrial

1

0

High-throughput

0.458

High

818266

XRN2
5'-3' exoribonuclease 2

1

0

High-throughput

0.458

High

818276

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

818279

RRP15
Ribosomal RNA-processing protein 15

1

0

High-throughput

0.458

High

818287

SGO1
Shugoshin

1

0

High-throughput

0.458

High

818300

NOP58
Nucleolar protein 58

1

0

High-throughput

0.458

High

526811

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

677848

RDS1
Regulator of drug sensitivity 1

1

0

High-throughput

0.438

High

455411

RS19B
Small ribosomal subunit protein eS19B

1

2

High-throughput

0.437

High

504240

RL31A
Large ribosomal subunit protein eL31A

1

1

High-throughput

0.437

High

514006

RL18B
Large ribosomal subunit protein eL18B

1

1

High-throughput

0.437

High

514146

RS16B
Small ribosomal subunit protein uS9B

1

2

High-throughput

0.437

High

655465

RS3A2
Small ribosomal subunit protein eS1B

1

2

High-throughput

0.437

High

799664

TPS3
Trehalose synthase complex regulatory subunit TPS3

1

1

High-throughput

0.437

High

799684

TSL1
Trehalose synthase complex regulatory subunit TSL1

1

1

High-throughput

0.437

High

818238

RS29A
Small ribosomal subunit protein uS14A

1

1

High-throughput

0.437

High

818239

RS29B
Small ribosomal subunit protein uS14B

1

1

High-throughput

0.437

High

818242

RSSA2
Small ribosomal subunit protein uS2B

1

1

High-throughput

0.437

High

383725

RS17A
Small ribosomal subunit protein eS17A

2

0

High-throughput

0.305

High

503071

RS22A
Small ribosomal subunit protein uS8A

2

0

High-throughput

0.305

High

778357

RS27A
Small ribosomal subunit protein eS27A

2

0

High-throughput

0.305

High

802202

RS20
Small ribosomal subunit protein uS10

2

0

High-throughput

0.305

High

818246

RS12
Small ribosomal subunit protein eS12

2

0

High-throughput

0.305

High

818263

RS15
Small ribosomal subunit protein uS19

2

0

High-throughput

0.305

High

806851

MNL1
ER degradation-enhancing alpha-mannosidase-like protein 1

1

0

High-throughput

0.265

Low

818298

LSP1
Sphingolipid long chain base-responsive protein LSP1

1

0

High-throughput

0.265

Low

482026

C1TM
C-1-tetrahydrofolate synthase, mitochondrial

1

0

High-throughput

0.249

Low

503498

RS28B
Small ribosomal subunit protein eS28B

1

0

High-throughput

0.249

Low

511667

RS23B
Small ribosomal subunit protein uS12B

1

0

High-throughput

0.249

Low

511803

RS24A
Small ribosomal subunit protein eS24A

1

0

High-throughput

0.249

Low

511934

RS30A
Small ribosomal subunit protein eS30A

1

0

High-throughput

0.249

Low

512085

RS4A
Small ribosomal subunit protein eS4A

1

0

High-throughput

0.249

Low

514662

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.249

Low

557599

NAT1
N-terminal acetyltransferase A complex subunit NAT1

1

0

High-throughput

0.249

Low

599029

PFKA2
ATP-dependent 6-phosphofructokinase subunit beta

1

0

High-throughput

0.249

Low

688899

RS5
Small ribosomal subunit protein uS7

1

0

High-throughput

0.249

Low

751411

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

0

High-throughput

0.249

Low

803261

OTU2
OTU domain-containing protein 2

1

0

High-throughput

0.249

Low

812341

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

818234

RL34B
Large ribosomal subunit protein eL34B

1

0

High-throughput

0.249

Low

818248

PSP2
Protein PSP2

1

0

High-throughput

0.249

Low

818255

BRE5
UBP3-associated protein BRE5

1

0

High-throughput

0.249

Low

818269

CLU
Clustered mitochondria protein 1

1

0

High-throughput

0.249

Low

818273

TMA64
Translation machinery-associated protein 64

1

0

High-throughput

0.249

Low

818281

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

818289

HRK1
Serine/threonine-protein kinase HRK1

1

0

High-throughput

0.249

Low

818303

RS21B
Small ribosomal subunit protein eS21B

1

0

High-throughput

0.249

Low

818304

RS25A
Small ribosomal subunit protein eS25A

1

0

High-throughput

0.249

Low

818265

NU116
Nucleoporin NUP116/NSP116

1

0

Small-scale

0.232

Low


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Last updated: 11Aug2025