HitPredict

Interactor 1: XRCC5 (P13010)
X-ray repair cross-complementing protein 5 (EC 3.6.4.-) (86 kDa subunit of Ku antigen) (ATP-dependent DNA helicase 2 subunit 2) (ATP-dependent DNA helicase II 80 kDa subunit) (CTC box-binding factor 85 kDa subunit) (CTC85) (CTCBF) (DNA repair protein XRCC5) (Ku80) (Ku86) (Lupus Ku autoantigen protein p86) (Nuclear factor IV) (Thyroid-lupus autoantigen) (TLAA) (X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining))
Gene: XRCC5

Interactor 2: TNIP1 (Q15025)
TNFAIP3-interacting protein 1 (A20-binding inhibitor of NF-kappa-B activation 1) (ABIN-1) (HIV-1 Nef-interacting protein) (Nef-associated factor 1) (Naf1) (Nip40-1) (Virion-associated nuclear shuttling protein) (VAN) (hVAN)
Gene: TNIP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36574265
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 732 Hs			1 636
+	Hs
		148341 XRCC5_HUMAN (1-732): 0: 755: 100.00		CTRO_HUMAN (51-557): 1.5e-16: 86.2: 14.12
+	Hs
		523770 XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49		TNIP1_HUMAN (1-636): 6.24e-78: 262: 100.00
+	Hs
		148340 XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49		CTRO_HUMAN (51-557): 1.5e-16: 86.2: 14.12
+	Hs
		523555 XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49		MYH10_HUMAN (210-571): 5.78e-13: 74.6: 10.48
+	Hs
		523554 XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49		MYH9_HUMAN (267-566): 1.17e-09: 63.8: 13.33