Protein: MCFS2
Medium-chain fatty acid ethyl ester synthase/esterase 2 (Alcohol O-acetyltransferase) (EC 2.3.1.84, EC 3.1.1.-) (Ethanol hexanoyl transferase 1)

Gene: MCFS2, EHT1
Organism: Saccharomyces cerevisiae S288C
Interactions: 56
UniProt ID: P38295

Gene Ontology (top 5):
GO:0004026 - alcohol O-acetyltransferase activity
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane
GO:0005811 - lipid droplet
GO:0006629 - lipid metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

797543

MCFS2
Medium-chain fatty acid ethyl ester synthase/esterase 2

2

0

Small-scale

0.728

High

757609

TGL1
Sterol esterase TGL1

1

1

High-throughput

0.698

High

702306

MGLL
Monoglyceride lipase

1

0

High-throughput

0.663

High

797553

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

0

High-throughput

0.559

High

796231

FAT1
Very long-chain fatty acid transport protein

1

3

High-throughput

0.541

High

797551

AYR1
NADPH-dependent 1-acyldihydroxyacetone phosphate reductase

1

1

High-throughput

0.541

High

797565

YEH1
Sterol esterase 1

1

1

High-throughput

0.541

High

763176

TOM20
Mitochondrial import receptor subunit TOM20

1

0

High-throughput

0.518

High

763669

RER2
Dehydrodolichyl diphosphate synthase complex subunit RER2

1

0

High-throughput

0.518

High

797544

ERG7
Lanosterol synthase ERG7

1

0

High-throughput

0.518

High

797545

TCD1
tRNA threonylcarbamoyladenosine dehydratase 1

1

0

High-throughput

0.518

High

797558

ALO
D-arabinono-1,4-lactone oxidase

1

0

High-throughput

0.518

High

797568

PSK2
Serine/threonine-protein kinase PSK2

1

2

High-throughput

0.501

High

797548

RSP5
E3 ubiquitin-protein ligase RSP5

1

0

High-throughput

0.480

High

752189

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.479

High

797564

LEC1
PX domain-containing protein LEC1

1

0

Small-scale

0.460

High

367013

ATPB
ATP synthase subunit beta, mitochondrial

1

0

High-throughput

0.458

High

579293

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.458

High

679613

CDC48
Cell division control protein 48

1

0

High-throughput

0.458

High

748737

YPT7
Ypt/Rab-type GTPase YPT7

1

0

Small-scale

0.458

High

797556

TOM22
Mitochondrial import receptor subunit TOM22

1

0

High-throughput

0.458

High

797562

COX20
Cytochrome c oxidase assembly protein COX20, mitochondrial

1

0

High-throughput

0.458

High

797563

BSC2
Bypass of stop codon protein 2

1

0

Small-scale

0.458

High

797571

SMC6
Structural maintenance of chromosomes protein 6

1

0

High-throughput

0.458

High

645921

DBF2
Cell cycle protein kinase DBF2

1

2

High-throughput

0.457

High

797570

SKM1
Serine/threonine-protein kinase SKM1

1

3

High-throughput

0.457

High

670632

SIS1
Protein SIS1

1

1

High-throughput

0.437

High

726975

HS104
Heat shock protein 104

1

1

High-throughput

0.437

High

523764

HSP71
Heat shock protein SSA1

1

6

High-throughput

0.407

High

797550

SSB2
Ribosome-associated molecular chaperone SSB2

1

7

High-throughput

0.407

High

797559

SED5
Integral membrane protein SED5

1

1

Small-scale

0.407

High

550759

INO1
Inositol-3-phosphate synthase

1

0

High-throughput

0.282

High

571825

SNA3
Protein SNA3

1

0

High-throughput

0.282

High

687051

PPZ1
Serine/threonine-protein phosphatase PP-Z1

1

0

High-throughput

0.282

High

743678

VATD
V-type proton ATPase subunit D

1

0

High-throughput

0.282

High

777204

KES1
Oxysterol-binding protein homolog 4

1

0

High-throughput

0.282

High

797547

BZZ1
Protein BZZ1

1

0

High-throughput

0.282

High

797549

GDI1
Rab GDP-dissociation inhibitor

1

0

High-throughput

0.282

High

797569

ENG2
Glucan endo-1,3-beta-D-glucosidase 2

1

0

High-throughput

0.282

High

797561

MYO5
Myosin-5

1

0

High-throughput

0.279

Low

692341

KCC1
Calcium/calmodulin-dependent protein kinase I

1

0

High-throughput

0.261

Low

794265

CHK1
Serine/threonine-protein kinase CHK1

1

0

High-throughput

0.261

Low

647761

RFA1
Replication factor A protein 1

1

0

Small-scale

0.251

Low

748365

SC61A
Protein transport protein SEC61

1

0

High-throughput

0.249

Low

794957

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

797546

RPN1
26S proteasome regulatory subunit RPN1

1

0

High-throughput

0.249

Low

797552

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

797554

HGH1
Protein HGH1

1

0

Small-scale

0.249

Low

797555

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.249

Low

797557

PESC
Pescadillo homolog

1

0

High-throughput

0.249

Low

797560

PDS5
Sister chromatid cohesion protein PDS5

1

0

High-throughput

0.249

Low

797567

YAP7
AP-1-like transcription factor YAP7

1

0

High-throughput

0.249

Low

503713

YB39B
Uncharacterized protein YBL039W-B

1

0

High-throughput

0.238

Low

528580

CP51
Lanosterol 14-alpha demethylase CYP51

1

0

High-throughput

0.238

Low

797566

TLG2
t-SNARE affecting a late Golgi compartment protein 2

1

0

Small-scale

0.232

Low


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Last updated: 11Aug2025