HitPredict

Interactor 1: XRCC5 (P13010)
X-ray repair cross-complementing protein 5 (EC 3.6.4.-) (86 kDa subunit of Ku antigen) (ATP-dependent DNA helicase 2 subunit 2) (ATP-dependent DNA helicase II 80 kDa subunit) (CTC box-binding factor 85 kDa subunit) (CTC85) (CTCBF) (DNA repair protein XRCC5) (Ku80) (Ku86) (Lupus Ku autoantigen protein p86) (Nuclear factor IV) (Thyroid-lupus autoantigen) (TLAA) (X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining))
Gene: XRCC5

Interactor 2: ECT2 (Q9H8V3)
Protein ECT2 (Epithelial cell-transforming sequence 2 oncogene)
Gene: ECT2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	31586073, 22990118
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	BRCT~Ku, BRCT~Ku_C
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 732 Hs			1 914
+	Hs
		524009 XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		524780 XRCC5_HUMAN (1-732): 0: 755: 100.00		VAV_HUMAN (390-707): 1.61e-76: 269: 21.82
+	Hs
		523495 XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49		VAV_HUMAN (390-707): 1.61e-76: 269: 21.82