HitPredict

Interactor 1: XRCC5 (P13010)
X-ray repair cross-complementing protein 5 (EC 3.6.4.-) (86 kDa subunit of Ku antigen) (ATP-dependent DNA helicase 2 subunit 2) (ATP-dependent DNA helicase II 80 kDa subunit) (CTC box-binding factor 85 kDa subunit) (CTC85) (CTCBF) (DNA repair protein XRCC5) (Ku80) (Ku86) (Lupus Ku autoantigen protein p86) (Nuclear factor IV) (Thyroid-lupus autoantigen) (TLAA) (X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining))
Gene: XRCC5

Interactor 2: ZRAN1 (Q9UGI0)
Ubiquitin thioesterase ZRANB1 (EC 3.4.19.12) (TRAF-binding domain-containing protein) (hTrabid) (Zinc finger Ran-binding domain-containing protein 1)
Gene: ZRANB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.653

Property	Details
Experiments	32296183, 35944360, unassigned1304
Identification Methods	two hybrid, affinity chromatography technology, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 732 Hs			1 708
+	Hs
		524059 XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		525014 XRCC5_HUMAN (1-732): 0: 755: 100.00		RNF31_HUMAN (29-410): 7.77e-78: 271: 15.73
+	Hs
		523931 XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49		RNF31_HUMAN (29-410): 7.77e-78: 271: 15.73
+	Hs
		523595 XRCC6_HUMAN (3-609): 3.61e-141: 429: 14.49		NU153_HUMAN (109-348): 5.07e-09: 61.9: 11.11